$148 Cheap flights to Santa Cruz
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Top places to visit in Santa Cruz
Cheap flights to Santa Cruz from $148 One Way, $302 Round Trip
$302 return flights and $148 one-way flights to Santa Cruz were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| GYE | Puerto Baquerizo Moreno | June 19 to June 22 | $315 |
| UIO | Puerto Baquerizo Moreno | June 21 to June 29 | $357 |
| GYE | Santa Rosa | June 19 to June 22 | $425 |
| UIO | Santa Rosa | June 19 to June 23 | $435 |
| LIM | Puerto Baquerizo Moreno | June 21 to June 26 | $581 |
| LIM | Santa Rosa | June 21 to June 26 | $641 |
| JFK | Santa Rosa | June 19 to June 25 | $654 |
| MIA | Santa Rosa | June 19 to June 23 | $697 |
| JFK | Puerto Baquerizo Moreno | June 20 to June 26 | $710 |
Find The Perfect Hotel For After Your Flight
Score Epic Santa Cruz Accommodation Deals
Hotel Fiesta
"The hotel is a good, basic hotel for a one night stopover before boarding a Galapagos Island cruise. Egg station for breakfast. Pool, deck chairs and billiards table."
Reviewed on Jun 11, 2026
Hotel el descanso del Guia
"Nice and clean hotel, nice and professional staff love my staying at el descanso del guía"
Reviewed on Jun 7, 2026
Maidith Galapagos Inn
"Good breakfast"
Reviewed on Jun 12, 2026
Ikala Galapagos Hotel
"Amazing place"
Reviewed on Jun 16, 2026
Need a Car For After Your Flight?
Economy
Compact
Midsize
SUV
Santa Cruz
Orbitz is your one stop for guaranteed low prices on Santa Cruz flights, as well as budget deals on hotels and rental cars. Use our state of the art mobile tools to get great deals and constant updates on the status of your trip.
Save Big On Car Rentals Too
Orbitz will find you discount air fare for flights to Santa Cruz and you can rent a car at the same time. With Orbitzyou will get a discount on the rental and have your car waiting for you when you land.
Get Free Travel Advice By Calling the Orbitz Hotline
Our experts will make things even easier by helping you to find the best budget flights to Santa Cruz Just call our toll free hotline at 1-800-649-9920 and one of our travel advisors will be happy to assist you with everything from your flight to hotel room.
Book Travel on the Fly with Orbitz on the Go
Our state of the art mobile apps will allow you to book cheap flights to Santa Cruz from your smartphone too. Discount airfare is not all; you can also find mobile-only hotel deals or check the status of your flight using this free app. So, when you’re on the go, why not take Orbitz with you?
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.