Santa Cruz Vacation Rentals

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Santa Cruz Vacation Rentals

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

3.5 out of 5
Calle Las Azucenas No. 127 Santa Cruz Santa Cruz
$39 nightly
The price is $39 total per night
$39 total
Mar 8 - Mar 9
At Premium Suites Deluxe Aparthotel Equipetrol, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. There's free parking, and an airport shuttle (available 24 hours) for USD 22 per vehicle roundtrip. The front desk is staffed 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a meeting room, a terrace, and laundry facilities.
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45 Santa Cruz
Guests of Apart Hotel Premium Suites Santa Cruz enjoy free WiFi in public areas, a terrace, and laundry facilities. You can take advantage of free parking, along with an airport shuttle (available on request) for USD 24 per vehicle roundtrip. Staff members are on hand to provide tour or ticket assistance, luggage storage, and a safe deposit box at the front desk.
Kitchen
Parking included
Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

2.5 out of 5
Equipetrol Santa Cruz Departamento de Santa Cruz
$53 nightly
The price is $53 total per night
$53 total
Apr 5 - Apr 6
Guests staying at Equipetrol Suites Apart Hotel enjoy free WiFi in public areas, laundry facilities, and a hair salon. Airport transportation is made easy with a shuttle from the airport to the hotel (available 24 hours) for USD 12 per vehicle. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include an ATM, a TV in a common area, and a convenience store.
Terranova Suites

Terranova Suites

3.5 out of 5
7º Anillo 400 mts al Oeste de Santa Cruz Santa Cruz
$47 nightly
The price is $47 total per night
$47 total
Mar 12 - Mar 13
Guests of Terranova Suites enjoy features like an outdoor pool, free WiFi in public areas, and laundry facilities. You can take advantage of free parking if you drive. A multilingual staff is on hand to assist with tours or tickets, dry cleaning/laundry, and securing valuables. Additional amenities include a vending machine, a garden, and a porter/bellhop.
Apart Hotel Toborochi

Apart Hotel Toborochi

3 out of 5
Jaime Freyre 7 Santa Cruz
At Apart Hotel Toborochi, guests have access to an outdoor pool, free WiFi in public areas, and a business center. You can take advantage of limited parking, along with a shuttle from the hotel to the airport (available 24 hours) for USD 15 per vehicle. Multilingual staff at the 24-hour front desk can assist with concierge services, securing valuables, and luggage storage. Additional amenities include a meeting room, a terrace, and laundry facilities.
Pool
Kitchen
AMERICA APARTMENTS

AMERICA APARTMENTS

3 out of 5
61 Carandí Santa Cruz Departamento de Santa Cruz
$55 nightly
The price is $55 total per night
$55 total
Mar 9 - Mar 10
Guests of AMERICA APARTMENTS enjoy features like an outdoor pool, free WiFi in public areas, and laundry facilities. There's free offsite parking if you drive. Friendly staff can provide front-desk service during limited hours, and also offer advice about sightseeing.
Samaipata Glamping

Samaipata Glamping

3.5 out of 5
Samaipata Samaipata Departamento de Santa Cruz
$240 nightly
The price is $240 total per night
$240 total
Mar 9 - Mar 10
Guests staying at Samaipata Glamping enjoy access to a winery, an outdoor pool, and a sauna. If you drive, take advantage of free parking. Additional amenities include free WiFi in public areas, a hot tub, and free use of bicycles.
COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!

COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!

Santa Cruz de la Sierra Departamento de Santa Cruz
$67 nightly
The price is $67 total per night
$67 total
Mar 8 - Mar 9
At this condo, guests have access to features like laundry facilities.
Dppto Luminoso y Lujoso en Equipe Zona Empresarial

Dppto Luminoso y Lujoso en Equipe Zona Empresarial

Santa Cruz de la Sierra Departamento de Santa Cruz
$65 nightly
The price is $65 total per night
$65 total
Mar 8 - Mar 9
At this apartment, guests have access to features like laundry facilities.
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Santa Cruz de la Sierra Departamento de Santa Cruz
$48 nightly
The price is $48 total per night
$48 total
Mar 8 - Mar 9
At this apartment, guests have access to features like laundry facilities. This smoke-free apartment building also has barbecue grills.
Casa Vida

Casa Vida

3.5 out of 5
Condominio Club Campestre Santa Cruz Santa
At Casa Vida, guests enjoy features like an outdoor pool, a children's pool, and free WiFi in public areas. There's free parking, as well as a free shuttle from the airport to the hotel (available 24 hours). Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and tours or tickets. Other amenities at this family-friendly vacation home include free use of bicycles, laundry facilities, and a picnic area.
Confortable and Exclusive Apart. Excl Ubicación 5+

Confortable and Exclusive Apart. Excl Ubicación 5+

Santa Cruz de la Sierra Departamento de Santa Cruz
At this apartment, guests have access to features like laundry facilities.
Apartamento confortable para 2 personas

Apartamento confortable para 2 personas

Santa Cruz de la Sierra Departamento de Santa Cruz
$42 nightly
The price is $42 total per night
$42 total
Mar 11 - Mar 12
This apartment is a smoke-free apartment building.
Elegant apartment in excellent location

Elegant apartment in excellent location

Santa Cruz de la Sierra Departamento de Santa Cruz
At this apartment, guests have access to a gym, a sauna, and a hot tub. This smoke-free apartment building also has barbecue grills.
"Modern 2-bedroom apartment in an exclusive building in Santa Cruz, Bolivia."

"Modern 2-bedroom apartment in an exclusive building in Santa Cruz, Bolivia."

Santa Cruz de la Sierra Departamento de Santa Cruz
At this apartment, guests have access to a gym, laundry facilities, and barbecue grills.
Montefuego Samaipata

Montefuego Samaipata

4 out of 5
5 km de la plaza principal de Samaipata Samaipata Santa Cruz
Guests staying at Montefuego Samaipata enjoy a full-service spa, free WiFi in public areas, and laundry facilities. There's free parking if you drive. Helpful staff can provide tour or ticket assistance and luggage storage. Other amenities at this spa aparthotel include local meal delivery service, barbecue grills, and a picnic area.
Studio apartment in Equipetrol

Studio apartment in Equipetrol

Santa Cruz de la Sierra Departamento de Santa Cruz
At this apartment, guests have access to features like laundry facilities.
Elegant Condominium-santa Cruz

Elegant Condominium-santa Cruz

Santa Cruz de la Sierra Santa Cruz Department
$60 nightly
The price is $60 total per night
$60 total
Mar 8 - Mar 9
At this houseboat, guests have access to features like laundry facilities.
Don't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Santa Cruz

    Ibis Santa Cruz DE LA Sierra

    Ibis Santa Cruz DE LA Sierra

    AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
    $55 nightly
    The price is $55 total per night from Mar 8 to Mar 9
    $55 total
    Mar 8 - Mar 9
    9.6/10 Exceptional! (92 reviews)
    Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

    Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

    Ave. San Martin, #455 Santa Cruz
    $136 nightly
    The price is $136 total per night from Mar 16 to Mar 17
    $136 total
    Mar 16 - Mar 17
    9/10 Wonderful! (363 reviews)
    Camino Real Hotel

    Camino Real Hotel

    Av. San Martín y 4to. Anillo Santa Cruz
    $126 nightly
    The price is $126 total per night from Apr 6 to Apr 7
    $126 total
    Apr 6 - Apr 7
    9/10 Wonderful! (420 reviews)

Orbitz makes it easy to find vacation rentals in Santa Cruz 

🏠 What is the best price for a Santa Cruz vacation rental?


Santa Cruz rentals range between $39 and $240 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in Santa Cruz can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next Santa Cruz getaway. Orbitz filters your search results so you can find the best Santa Cruz vacation rental for you. We have tons of options.


🏠 Are cancellations free on Santa Cruz vacation rentals with Orbitz?


You may be able to cancel or amend your Santa Cruz vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in Santa Cruz?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in Santa Cruz by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My TripsOpens in a new window on your Orbitz account page to find the right information contact. If you need more help, visit our Customer ServiceOpens in a new window page. 


🏠 What are the advantages of booking a vacation rental in Santa Cruz?


When you book a Santa Cruz vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in Santa Cruz?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across Santa Cruz—with plenty of hidden gems. We also have plenty of inventory in Santa Cruz main cities and near popular attraction spots.


🏠 Why should I book my Santa Cruz vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream Santa Cruz vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


More to Explore