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Featured Vacation Homes in Des Moines

4 Bedroom, Sleeps 10, Heart of Beaverdale Clean, Room to Spread out
4 Bedroom, Sleeps 10, Heart of Beaverdale Clean, Room to Spread out
Des Moines, IA
Guests staying at this vacation home enjoy a water park, barbecue grills, and a garden.
Acreage Intown 4 BR, 2 Bath 2,300 sq ft W/pool, gym + Sports
Acreage Intown 4 BR, 2 Bath 2,300 sq ft W/pool, gym + Sports
Urbandale, IA
Features of this vacation home include an outdoor pool and a fitness center.
Large Brick Ranch Home With a 3 BR Option to Rent on Quiet, Private, Deadend St
Large Brick Ranch Home With a 3 BR Option to Rent on Quiet, Private, Deadend St
West Des Moines, IA
This vacation home is a smoke-free vacation home.
This House is in a Quiet Neighborhood Near Major Attractions
This House is in a Quiet Neighborhood Near Major Attractions
Pleasant Hill, IA
Guests staying at this vacation home enjoy a water park, a garden, and barbecue grills.
Huge 7 Bedroom Brick Ranch Style Home With 12 Beds
Huge 7 Bedroom Brick Ranch Style Home With 12 Beds
West Des Moines, IA
This vacation home is a smoke-free vacation home.
4 Bedroom 2 Bath House - Walking Distance to Gray's Lake - Near Downtown
4 Bedroom 2 Bath House - Walking Distance to Gray's Lake - Near Downtown
Des Moines, IA
This vacation home is a smoke-free vacation home.
Dream Home in Metro Suburb w/ Self Check In
Dream Home in Metro Suburb w/ Self Check In
Ankeny, IA
Guests staying at this vacation home enjoy a water park, a garden, and barbecue grills.
Old Farm House Located in the Country and Only 15 Minutes to Jordon Creek Mall
Old Farm House Located in the Country and Only 15 Minutes to Jordon Creek Mall
Norwalk, IA
Guests staying at this vacation home have access to barbecue grills and a garden.
Huge 1-2 BR 1,700 Sq Ft Suite With Pool & Gymnasium on a Private In-town Acreage
Huge 1-2 BR 1,700 Sq Ft Suite With Pool & Gymnasium on a Private In-town Acreage
Urbandale, IA
Features of this vacation home include an indoor pool and an outdoor pool.
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Des Moines Vacation Homes

Book vacation homes in Des Moines
Next time you take a group getaway top Des Moines, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Des Moines vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Des Moines vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Des Moines; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Des Moines rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Des Moines is sure to be a winner.

Hotel Options in Des Moines

See all 273 Properties in Des Moines
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.