Book 5 Star Hotels in Panama City
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Panama City 5 Stars Hotels

Quality Inn & Conference Center

Comfort Inn & Suites Panama City North

La Quinta Inn & Suites by Wyndham Panama City

Comfort Inn & Suites

Hilton Garden Inn Panama City Airport

Ramada by Wyndham Panama City

Best Western Plus Panama City Hotel

Holiday Inn Panama City by IHG

Hotel Indigo Panama City Marina by IHG
Best 5 star hotels in Panama City
Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Panama City. After all, treating yourself to the finer things is what vacations are about.
What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Panama City hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.
What amenities can I expect at a 5 star hotel?
Panama City 5 star hotels and resorts typically offer luxury amenities such as:
- Gourmet restaurant
- Full-service fitness center with pool
- Luxury spa
- Welcome gifts upon arrival
- Top-of-the-line beds and linens
- Designer personal care products
- Premium cable, free Wi-Fi and device docking stations
How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Panama City with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place:
- Search hotels by price, ranging from $57 to $135
- Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
- Choose from 15,399 5 star hotels in Panama City!
Panama City hotels essential information
Accommodation | 15,399 hotels |
---|---|
Lowest Price | $57 |
Highest Price | $135 |
Popular hotels | Quality Inn & Conference Center, Comfort Inn & Suites Panama City North, La Quinta Inn & Suites by Wyndham Panama City, Comfort Inn & Suites, Hilton Garden Inn Panama City Airport, Ramada by Wyndham Panama City, Best Western Plus Panama City Hotel, Holiday Inn Panama City by IHG, Hotel Indigo Panama City Marina by IHG |
Recent Reviews

Hilton Garden Inn Panama City Airport
More to Explore
- 3 Star Hotels in Santa Monica
- 5 Star Hotels in Hollywood Beach
- Beach Resorts & in Downtown Panama City
- Cheap Hotels in Downtown Panama City
- Hotels with Pool in Downtown Panama City
- Hotels with Bar in Downtown Panama City
- Hotels with Free Breakfast in Downtown Panama City
- Hotels with Free Parking in Downtown Panama City
- Hotels with Shopping in Downtown Panama City
- 4 Star Hotels in Watersound
- 3 Star Hotels in Wewahitchka
- 5 Star Hotels in Majestica Beach
- 2 Star Hotels in Mexico Beach Business Center
- 5 Star Hotels in Mexico Beach Business Center
- Hotels near Science and Discovery Center of Northwest Florida
- 4 Star Hotels in Silver Sands Beach
- Hotels near Port Panama City
- Hotels near Ascension Sacred Heart Bay
- 3 Star Hotels in Laguna Beach Plaza
- Hotels near Cove Park
- Hotels near Linos Park
- Hotels near Florida State University Panama City
- 2 Star Hotels in Holiday Beach
- 3 Star Hotels in Holiday Beach
- 4 Star Hotels in Holiday Beach
- 5 Star Hotels in Holiday Beach
- Hotels near Meadows Course at Bay Point Resort
- Beach Resorts & in Gulf Coast Development
- Hotels with WiFi in Gulf Coast Development
- Gulf Coast Development Hotels
- 2 Star Hotels in Rosemary Beach
- 3 Star Hotels in Rosemary Beach
- 5 Star Hotels in Rosemary Beach
- 4 Star Hotels in Seagrove Beach
- Hotels near Kaleidoscope Theater
- 4 Star Hotels in Ebro
- 4 Star Hotels in Gulf Highlands
- 5 Star Hotels in Mar-a-Lago
- 4 Star Hotels in Upper Grand Lagoon
- 4 Star Hotels in Mexico Beach
- 2 Star Hotels in Callaway
- Hotels near Gulf Coast State College
- Guest Houses in Cedar Grove
- Cedar Grove Hotels
- Motels in Cedar Grove
- 5 Star Hotels in Sunny Hills
- Beach Resorts & in Bunkers Cove
- Hotels with Free Breakfast in Bunkers Cove
- Hotels with Pool in Drummond And Ware
- Hotels near Oliver Stadium
- Hotels near Panama City Mall
- Houseboats in Parker
- Resorts in Parker
- Hotels near Marina Civic Center
- Hotels near Oakland Terrace Park
- Farmstay in Shell Island
- Apartments in Shell Island
- Cabin Rentals in Shell Island
- Cottages in Shell Island
- Shell Island Hotels
- Rv Parks in Shell Island
- Villas in Shell Island
- 5 Star Hotels in Lullwater Beach
- 4 Star Hotels in SeaNest Village
- All Inclusive Resorts & in Bay County
- Fishing Resorts & in Bay County
- Hotels with Pool in Bay County
- Hotels with Free Breakfast in Bay County
- Hotels with a Gym in Bay County
- Hotels on the Lake in Bay County
- Luxury Hotels in Bay County
- Hotels on the River in Bay County
- Spa Resorts & in Bay County
- Waterpark Hotels & Resorts in Bay County
- Hotels with a Wedding Venue in Bay County
- Beach Resorts & in Destin
- Hotels with Pool in Highland City
- Hotels near Panama City Marina
- 5 Star Hotels in Gulf Mist
- Golf Resorts & in St Andrews
- Spa Resorts & in St Andrews
- Hotels with an Indoor Pool in Sherwood
- 4 Star Hotels in Treetop
- Hotels near Martin Theatre
- Apartments in Pretty Bayou
- Houseboats in Pretty Bayou
- 4 Star Hotels in Panama City Beach
- 5 Star Hotels in Panama City Beach
- Condo Rentals in Panama City Beach
- Cheap Hotels in Panama City Beach
- Panama City Beach Hotels