Cheap flights from MEX to TMS (Mexico City Intl. to São Tomé Intl.)

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Hotel Ideas near São Tomé Intl.

Airport Hotels near São Tomé Intl.

Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
The price is $209 total per night from Nov 15 to Nov 16
$209 total
per night
Nov 15 - Nov 16
Book a stay at this beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
9.4/10 Exceptional! (69 reviews)
"Clean and beautiful grounds, but the customer service is lacking!"

Reviewed on Oct 9, 2026

Omali São Tomé – Principe Collection
Hotel Praia

Hotel Praia

3.5 out of 5
Praia Lagarto - Cx. Postal 61 São Tomé
The price is $187 total per night from Dec 13 to Dec 14
$187 total
per night
Dec 13 - Dec 14
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon ...
Hotel Praia
Hotel Vitória

Hotel Vitória

3 out of 5
Estrada do Aeroporto- Entrada de Saton São Tomé Água Grande District
The price is $67 total per night from Nov 13 to Nov 14
$67 total
per night
Nov 13 - Nov 14
Stay at this hotel in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate Factory ...
7.6/10 Good! (5 reviews)
"Tv channel was terrible, breakfast service not good enough, most times was problem with water, electricity and wify, the staff were friendly"

Reviewed on Nov 15, 2019

Hotel Vitória
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In São Tomé Island

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
The price is $240 total per night from Nov 13 to Nov 14
$240 total
per night
Nov 13 - Nov 14
Book a stay at this luxury hotel in São Tomé. Enjoy free WiFi, free parking, and room service. Popular attractions Estadio Nacional 12 de Julho and Cloçon Téla ...
8.2/10 Very Good! (84 reviews)
"The location and pool were excellent; however, the gym was very mediocre with outdated machines and no other amenities besides the pool and sauna were available. Also, no beach access other than a trashy public beach near the hotel."

Reviewed on Nov 10, 2026

Pestana São Tomé
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
The price is $209 total per night from Nov 15 to Nov 16
$209 total
per night
Nov 15 - Nov 16
Book a stay at this beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
9.4/10 Exceptional! (69 reviews)
"Clean and beautiful grounds, but the customer service is lacking!"

Reviewed on Oct 9, 2026

Omali São Tomé – Principe Collection
Hotel Central

Hotel Central

3.5 out of 5
Rua de Angola São Tomé São Tomé
The price is $54 total per night from Nov 22 to Nov 23
$54 total
per night
Nov 22 - Nov 23
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and an airport shuttle (surcharge). Popular attractions Cloçon Téla ...
8/10 Very Good! (29 reviews)
"While the room, location and property were great. Staff lacks initiative, I asked why no one answered my emails about a airport transfer which is advertised that it can be arranged upon request, I was told that the person that usually handles emails and airport transfers is sick, hence no response. ..."

Reviewed on Oct 21, 2026

Hotel Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MEX to TMS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MEX Address & GPS
Address:
Mexico City ,
Mexico
IATA Code:
MEX
Longitude:
-99.072778
Latitude:
19.435278
Time Zone:
America/Mexico_City
TMS Address & GPS
Address:
Sao Tome Island ,
Sao Tome and Principe
IATA Code:
TMS
Longitude:
6.725
Latitude:
0.378333
Time Zone:
Africa/Sao_Tome

Frequently asked questions

What airlines have the most flights from Mexico Airport to TMS?
If you're wanting to book with an airline that offers direct flights from Mexico City Intl. Airport (MEX) to TMS, you're out of luck. You'll have to make at least one stop to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.