$191 Cheap flight deals from Sioux Falls (FSD) to Biloxi (MOB)

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Airfares from $191 One Way, $259 Round Trip from Sioux Falls to Biloxi

Prices starting at $259 for return flights and $191 for one-way flights to Biloxi were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jan 6 - Thu, Jan 15
FSD
Sioux Falls
MSY
New Orleans
$259 Roundtrip, found 3 days ago
$259
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jan 6 from Sioux Falls to New Orleans, returning Thu, Jan 15, priced at $259 found 3 days ago
Tue, Jan 6 - Thu, Jan 15
FSD
Sioux Falls
MSY
New Orleans
$259 Roundtrip, found 3 days ago
$259
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jan 6 from Sioux Falls to New Orleans, returning Thu, Jan 15, priced at $259 found 3 days ago
Mon, Jan 5 - Wed, Jan 14
FSD
Sioux Falls
MSY
New Orleans
$259 Roundtrip, found 3 days ago
$259
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Jan 5 from Sioux Falls to New Orleans, returning Wed, Jan 14, priced at $259 found 3 days ago
Tue, Dec 9 - Mon, Dec 15
FSD
Sioux Falls
MSY
New Orleans
$263 Roundtrip, found 6 days ago
$263
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Dec 9 from Sioux Falls to New Orleans, returning Mon, Dec 15, priced at $263 found 6 days ago
Sat, Dec 6 - Wed, Dec 10
FSD
Sioux Falls
MSY
New Orleans
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Dec 6 from Sioux Falls to New Orleans, returning Wed, Dec 10, priced at $263 found 1 day ago

Biloxi economy flight packages

Price found within the past 48 hours. Click for updated prices.
Inn on St. Peter
3.0-star property

Inn on St. Peter

8.6/10 Excellent! (1,011 reviews)

Dec 6 - Dec 10

4 night stay

Sioux Falls (FSD) to New Orleans (MSY)

American Airlines • Non-stop roundtrip • Coach
Price was $583, price is now $501 per person
$501
per person
found 1 day ago
We loved our stay here. We were booked in two separate rooms, and they were both really clean. It was easy to get down to Bourbon or any of the main sites we wanted to go to but far enough that we weren't bothered with any outside noise. The property is beautiful. We did utilize the parking at one of their other properties, but it was only a 15 minute walk away and had no issues leaving our car for a couple of days. We would definitely stay here again.

Reviewed on Oct 2, 2025

Inn on St Ann
3.0-star property

Inn on St Ann

8.4/10 Very Good! (1,002 reviews)

Dec 6 - Dec 10

4 night stay

Sioux Falls (FSD) to New Orleans (MSY)

American Airlines • Non-stop roundtrip • Coach
Price was $583, price is now $501 per person
$501
per person
found 1 day ago
I had a small room, but the bed was comfortable, the bathroom was nice, and the area was very walkable

Reviewed on Jun 6, 2025

Bluegreen Club La Pension
3.0-star property

Bluegreen Club La Pension

9/10 Wonderful! (977 reviews)

Dec 6 - Dec 10

4 night stay

Sioux Falls (FSD) to New Orleans (MSY)

American Airlines • Non-stop roundtrip • Coach
Price was $690, price is now $594 per person
$594
per person
found 1 day ago
Smack dab in the French quarter, convenient store next store. Dining to the left and right, clean room! Will come back

Reviewed on Oct 7, 2025

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More About Flying To Biloxi from Sioux Falls

Route Information for Flights from Sioux Falls to Biloxi

Origin Airport IATA Code
FSD
Destination Airport IATA Code
MOB
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Sioux Falls to Biloxi

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Frequently asked questions

What is the shortest flight from Sioux Falls to Biloxi?
Traveling from Sioux Falls Regional Airport (FSD) to Louis Armstrong New Orleans Intl. Airport (MSY) will take a minimum of 3 hours and 32 minutes. Enjoy a beverage and get stuck into that book — it's a golden opportunity to sit back and relax.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.