$130 Cheap flight deals from Greenville - Spartanburg (GSP) to O'Fallon (STL)

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Airfares from $130 One Way, $272 Round Trip from Greenville - Spartanburg to O'Fallon

Prices starting at $272 for return flights and $130 for one-way flights to O'Fallon were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Dec 2 - Mon, Dec 7
GSP
Greenville
STL
St. Louis
$272 Roundtrip, found 1 day ago
$272
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Dec 2 from Greenville to St. Louis, returning Mon, Dec 7, priced at $272 found 1 day ago
Wed, Dec 2 - Mon, Dec 7
GSP
Greenville
STL
St. Louis
$276 Roundtrip, found 1 day ago
$276
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Dec 2 from Greenville to St. Louis, returning Mon, Dec 7, priced at $276 found 1 day ago
Wed, Dec 2 - Mon, Dec 7
GSP
Greenville
STL
St. Louis
$281 Roundtrip, found 1 day ago
$281
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Dec 2 from Greenville to St. Louis, returning Mon, Dec 7, priced at $281 found 1 day ago
Wed, Dec 2 - Mon, Dec 7
GSP
Greenville
STL
St. Louis
$281 Roundtrip, found 1 day ago
$281
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Dec 2 from Greenville to St. Louis, returning Mon, Dec 7, priced at $281 found 1 day ago
Wed, Dec 2 - Mon, Dec 7
GSP
Greenville
STL
St. Louis
$283 Roundtrip, found 1 day ago
$283
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Dec 2 from Greenville to St. Louis, returning Mon, Dec 7, priced at $283 found 1 day ago

O'Fallon economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
3.5-star property

The Wildwood Hotel

9.2/10 Wonderful! (1,657 reviews)

Nov 6 - Nov 8

2 night stay

Greenville (GSP) to St. Louis (STL)

Southwest Airlines • Non-stop • Coach

St. Louis (STL) to Greenville (GSP)

American Airlines • Non-stop • Coach
Price was $958, price is now $617 per person
$617
per person
found 23 hours ago

Residence Inn by Marriott St. Louis West County
3.0-star property

Residence Inn by Marriott St. Louis West County

9.2/10 Wonderful! (266 reviews)

Nov 6 - Nov 11

5 night stay

Greenville (GSP) to St. Louis (STL)

Southwest Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,181, price is now $691 per person
$691
per person
found 22 hours ago
Ive stayed here before. Rooms are nice because they have a desk kitchen snd couch. Bed was not good. We stayed here because our ac went out. I called and confirmed pet friendly booked and paid for the room only to arrive and be told its $100 pet fee. Thats not fair or ok.

Reviewed on Sep 4, 2026

21C Museum Hotel St Louis
4.5-star property

21C Museum Hotel St Louis

9/10 Wonderful! (2,085 reviews)

Nov 6 - Nov 11

5 night stay

Greenville (GSP) to St. Louis (STL)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $1,054, price is now $868 per person
$868
per person
found 22 hours ago

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More About Flying To O'Fallon from Greenville - Spartanburg

Route Information for Flights from Greenville - Spartanburg to O'Fallon

Origin Airport IATA Code
GSP
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Greenville - Spartanburg to O'Fallon

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You will have no problems finding budget flights from Greenville - Spartanburg to O'Fallon on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.