$116 Cheap flight deals from Knoxville (TYS) to Lowell (BOS)

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Airfares from $116 One Way, $297 Round Trip from Knoxville to Lowell

Prices starting at $297 for return flights and $116 for one-way flights to Lowell were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jul 24 - Sat, Jul 25
TYS
Knoxville
BOS
Boston
$297 Roundtrip, found 9 hours ago
$297
Roundtrip
found 9 hours ago
Select Delta flight, departing Fri, Jul 24 from Knoxville to Boston, returning Sat, Jul 25, priced at $297 found 9 hours ago
Fri, Jul 24 - Sat, Jul 25
TYS
Knoxville
BOS
Boston
$315 Roundtrip, found 9 hours ago
$315
Roundtrip
found 9 hours ago
Select Delta flight, departing Fri, Jul 24 from Knoxville to Boston, returning Sat, Jul 25, priced at $315 found 9 hours ago
Fri, Sep 25 - Mon, Sep 28
TYS
Knoxville
BOS
Boston
$320 Roundtrip, found 3 days ago
$320
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Sep 25 from Knoxville to Boston, returning Mon, Sep 28, priced at $320 found 3 days ago
Fri, Jul 24 - Sat, Jul 25
TYS
Knoxville
BOS
Boston
$329 Roundtrip, found 9 hours ago
$329
Roundtrip
found 9 hours ago
Select Delta flight, departing Fri, Jul 24 from Knoxville to Boston, returning Sat, Jul 25, priced at $329 found 9 hours ago
Mon, Jan 12 - Thu, Jan 15
TYS
Knoxville
MHT
Manchester
$336 Roundtrip, found 6 days ago
$336
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Jan 12 from Knoxville to Manchester, returning Thu, Jan 15, priced at $336 found 6 days ago

Lowell economy flight packages

Price found within the past 48 hours. Click for updated prices.
Eurostars The Boxer
4.0-star property

Eurostars The Boxer

8.6/10 Excellent! (1,323 reviews)

Dec 28 - Dec 31

3 night stay

Knoxville (TYS) to Boston (BOS)

American Airlines • Non-stop • Coach

Boston (BOS) to Knoxville (TYS)

United • Non-stop • Coach
Price was $829, price is now $672 per person
$672
per person
found 16 hours ago
Third time staying here and it’s perfect for sports fans heading to games at TD Garden!

Reviewed on May 6, 2025

The Whitney Hotel
4.0-star property

The Whitney Hotel

9.6/10 Exceptional! (475 reviews)

Dec 28 - Dec 31

3 night stay

Knoxville (TYS) to Boston (BOS)

American Airlines • Non-stop • Coach

Boston (BOS) to Knoxville (TYS)

United • Non-stop • Coach
Price was $1,100, price is now $844 per person
$844
per person
found 16 hours ago
What a gem in Boston! I've been to Boston many times and usually stay closer to the Downtown Crossing area. This time we stayed at the Whitney, choosing to try out that part of town. We loved it! Bigger than a boutique hotel, but small enough to feel intimate. Charles St is a great walking street, and we loved the location. The room was on the ground level (actually partly below ground) but was excellent! Well-appointed room, a good amount of space for Boston, and super professional staff. I'll be back when I come back to Boston

Reviewed on Jul 30, 2024

The Langham, Boston
5.0-star property

The Langham, Boston

9.6/10 Exceptional! (1,008 reviews)

Dec 28 - Dec 31

3 night stay

Knoxville (TYS) to Boston (BOS)

American Airlines • Non-stop • Coach

Boston (BOS) to Knoxville (TYS)

United • Non-stop • Coach
Price was $1,165, price is now $943 per person
$943
per person
found 16 hours ago
Was hoping for more.

Reviewed on Jul 31, 2025

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More About Flying To Lowell from Knoxville

Route Information for Flights from Knoxville to Lowell

Origin Airport IATA Code
TYS
Destination Airport IATA Code
BOS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Knoxville to Lowell

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.