$140 Cheap flight deals from Myrtle Beach (MYR) to Lenoir City (TYS)

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This Weekend's Flight Deals from Myrtle Beach to Lenoir City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 18 - Sun, Apr 19
MYR
Myrtle Beach Intl.
TYS
McGhee Tyson
$552 Roundtrip, found 23 hours ago
$552
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Apr 18 from Myrtle Beach Intl. to McGhee Tyson, returning Sun, Apr 19, priced at $552 found 23 hours ago

Airfares from $140 One Way, $342 Round Trip from Myrtle Beach to Lenoir City

Prices starting at $342 for return flights and $140 for one-way flights to Lenoir City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jul 9 - Sun, Jul 12
MYR
Myrtle Beach
TYS
Knoxville
$342 Roundtrip, found 3 days ago
$342
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Jul 9 from Myrtle Beach to Knoxville, returning Sun, Jul 12, priced at $342 found 3 days ago
Thu, Jul 9 - Sun, Jul 12
MYR
Myrtle Beach
TYS
Knoxville
$347 Roundtrip, found 3 days ago
$347
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Jul 9 from Myrtle Beach to Knoxville, returning Sun, Jul 12, priced at $347 found 3 days ago
Thu, Jul 9 - Sun, Jul 12
MYR
Myrtle Beach
TYS
Knoxville
$353 Roundtrip, found 3 days ago
$353
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Jul 9 from Myrtle Beach to Knoxville, returning Sun, Jul 12, priced at $353 found 3 days ago
Thu, Jul 9 - Sun, Jul 12
MYR
Myrtle Beach
TYS
Knoxville
$357 Roundtrip, found 3 days ago
$357
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Jul 9 from Myrtle Beach to Knoxville, returning Sun, Jul 12, priced at $357 found 3 days ago
Thu, Jul 9 - Sun, Jul 12
MYR
Myrtle Beach
TYS
Knoxville
$362 Roundtrip, found 3 days ago
$362
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Jul 9 from Myrtle Beach to Knoxville, returning Sun, Jul 12, priced at $362 found 3 days ago

Lenoir City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Brookside Lodge
3.0-star property

Brookside Lodge

8.6/10 Excellent! (2,166 reviews)

May 25 - May 29

4 night stay

Myrtle Beach (MYR) to Knoxville (TYS)

Delta • Coach

Knoxville (TYS) to Myrtle Beach (MYR)

Spirit Airlines • Coach
Price was $662, price is now $533 per person
$533
per person
found 7 hours ago
A place was a little older than we expected, especially for the price. Nice, easy walk to get pancake breakfast Sunday morning.

Reviewed on Nov 2, 2025

Stonebrook Lodge Cherokee
2.5-star property

Stonebrook Lodge Cherokee

9.2/10 Wonderful! (891 reviews)

May 25 - May 29

4 night stay

Myrtle Beach (MYR) to Knoxville (TYS)

Delta • Coach

Knoxville (TYS) to Myrtle Beach (MYR)

Spirit Airlines • Coach
Price was $655, price is now $538 per person
$538
per person
found 7 hours ago
We had a great stay at Stonebrook Lodge. Conveniently located directly across the street from Harrahs Casino. The hotel was clean, the bed was very comfortable, as well as the pillows (which is hard to find). The staff were friendly and helpful. If I had one critique, it would be the shower head. When talking a shower the water was spraying in every direction making it hard to rinse. I would recommend changing it out (could’ve just been in our room). We didn’t eat breakfast, so I can’t comment on that. Over all, I can confidently say, we’ll be back!

Reviewed on Mar 22, 2025

Edgewater Hotel - Gatlinburg
3.0-star property

Edgewater Hotel - Gatlinburg

8.6/10 Excellent! (2,723 reviews)

May 25 - May 29

4 night stay

Myrtle Beach (MYR) to Knoxville (TYS)

Delta • Coach

Knoxville (TYS) to Myrtle Beach (MYR)

Spirit Airlines • Coach
Price was $701, price is now $584 per person
$584
per person
found 7 hours ago
Staff throughout the hotel were very nice and accommodating. Breakfast staff were rude and not helpful. Would have been nice if healthy food would have been offered (i.e fruit or yogurt). Parking is always a little rough when you have large trucks. It would have been nice to know about the $15 per night packing fee. That was new to us. Overall a good place to stay very convenient to the strip and walking distance to everything in Gatlinburg.

Reviewed on Jan 10, 2026

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More About Flying To Lenoir City from Myrtle Beach

Route Information for Flights from Myrtle Beach to Lenoir City

Origin Airport IATA Code
MYR
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Myrtle Beach to Lenoir City

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.