$204 Cheap flight deals from Cancun (CUN) to Santo Domingo (SDQ)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Airfares from $204 One Way, $402 Round Trip from Cancun to Santo Domingo

Prices starting at $402 for return flights and $204 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 17 - Fri, Oct 24
CUN
Cancun
SDQ
Santo Domingo
$402 Roundtrip, found 7 hours ago
$402
Roundtrip
found 7 hours ago
Select Aeromexico flight, departing Fri, Oct 17 from Cancun to Santo Domingo, returning Fri, Oct 24, priced at $402 found 7 hours ago
Sat, Feb 14 - Mon, Feb 23
CUN
Cancun
SDQ
Santo Domingo
$405 Roundtrip, found 1 day ago
$405
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Sat, Feb 14 from Cancun to Santo Domingo, returning Mon, Feb 23, priced at $405 found 1 day ago
Thu, Nov 20 - Wed, Nov 26
CUN
Cancun
SDQ
Santo Domingo
$406 Roundtrip, found 6 days ago
$406
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Thu, Nov 20 from Cancun to Santo Domingo, returning Wed, Nov 26, priced at $406 found 6 days ago
Wed, Nov 19 - Tue, Nov 25
CUN
Cancun
SDQ
Santo Domingo
$419 Roundtrip, found 6 days ago
$419
Roundtrip
found 6 days ago
Select Copa flight, departing Wed, Nov 19 from Cancun to Santo Domingo, returning Tue, Nov 25, priced at $419 found 6 days ago
Mon, Oct 6 - Fri, Oct 10
CUN
Cancun
SDQ
Santo Domingo
$433 Roundtrip, just found
$433
Roundtrip
just found
Select Aeromexico flight, departing Mon, Oct 6 from Cancun to Santo Domingo, returning Fri, Oct 10, priced at $433 just found

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Coral Costa Caribe Beach Resort - All Inclusive
4.0-star property

Coral Costa Caribe Beach Resort - All Inclusive

7.8/10 Good! (2,328 reviews)

Oct 23 - Oct 27

4 night stay

Cancun (CUN) to Santo Domingo (SDQ)

Sterling Blue • Roundtrip • Coach
Price was $1,134, price is now $498 per person
$498
per person
found 1 day ago
Me encantó todo, puedo repetirlo nuevamente .

Reviewed on Aug 14, 2025

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive
4.5-star property

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive

8.8/10 Excellent! (2,827 reviews)

Oct 23 - Oct 27

4 night stay

Cancun (CUN) to Santo Domingo (SDQ)

Sterling Blue • Roundtrip • Coach
Save 100% on your flight
Price was $1,067, price is now $631 per person
$631
per person
found 1 day ago
Absolutely amazing. Maria from entertainment was so sweet and amazing!!! Would absolutely recommend!!

Reviewed on Jun 22, 2025

Bahia Principe Grand La Romana - All Inclusive
4.5-star property

Bahia Principe Grand La Romana - All Inclusive

8.4/10 Very Good! (2,605 reviews)

Oct 23 - Oct 27

4 night stay

Cancun (CUN) to Santo Domingo (SDQ)

Sterling Blue • Roundtrip • Coach
Save 100% on your flight
Price was $902, price is now $552 per person
$552
per person
found 1 day ago
The property is beautiful and very well kept. Easy to maneuver around from start to finish. The check in process was fast and everyone at the counter was super nice and helpful. The carts that help with luggage, moved efficiently and quickly getting everyone settled. Rooms were clean, stocked, and the temperature was nice and cool. The food was great and had a big variety. The staff at the main food area was always so nice and went above and beyond no matter how busy they were. Lala was amazing and always had a smile on her face. From what I saw, she was like that with everyone. Whatever she gets paid, its not enough on how that woman is always on the go. There was always something to do at the resort. The animation group was amazing in keeping everyone entertained. You can tell that they truly love their jobs because they gave it their all...EVERYDAY. We scheduled a tour and that was extremely fun. The man that schedules you was friendly and helpful as well. I went this time with no kids and saw how much the kids there had fun. I would absolutely love to repeat my visit with my children here.

Reviewed on Aug 13, 2025

Don't see what you're looking for?
See all available trips from Cancun to Santo Domingo
View all trips

More About Flying To Santo Domingo from Cancun

Route Information for Flights from Cancun to Santo Domingo

Origin Airport IATA Code
CUN
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Cancun to Santo Domingo

Whether you want to book cheap flights from Cancun to Santo Domingo or are looking for the perfect package holiday, Orbitz is your one-stop source. Taking the stress and expense out of travel, Orbitz helps you find the best fares for Cancun to Santo Domingo flights.

Make the Most of Your Vacation

Not only does Orbitz have cheap deals for Cancun to Santo Domingo flights, we can also help you plan your vacation in advance. Why wait in lengthy lines for tickets to shows, amusement parks, and other attractions when you could be making the most of your holiday? Add activities to your flight booking for fewer hassles once you arrive in Santo Domingo.

Planning on the Go

Book your flights from Cancun to Santo Domingo wherever you are with the Orbitz app for Android and iPhone. Or simply use m.orbitz.com on your mobile browser to search and book the Cancun to Santo Domingo flights that you want. And if you’re running late, you check your flight status and baggage claim information on your mobile device too too.

Craft Your Perfect Vacation

Orbitz takes the stress out of vacation planning with great deals on flights from Cancun to Santo Domingo, hotels, car rentals, cruises, and more. Mix and match results for your perfect trip, or book a complete vacation package.

Keep Informed With Orbitz

With Orbitz’s free alerts service, you will stay informed of flight or services disruptions to your Cancun to Santo Domingo flights. The alerts can be sent straight to your mobile phone or email.

Frequently asked questions

What is the shortest flight from Cancun to Santo Domingo?
Flying from Cancun Intl. Airport (CUN) to SDQ takes at least 3 hours and 58 minutes. Enjoy a wine and watch a movie or two — this is a great opportunity to sit back and relax.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.