$78 Cheap flight deals from Colorado Springs (DEN) to Middlesboro (TYS)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Colorado Springs to Middlesboro
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $78 One Way, $174 Round Trip from Colorado Springs to Middlesboro
Prices starting at $174 for return flights and $78 for one-way flights to Middlesboro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Middlesboro economy flight packages
Hilton Knoxville
Aug 7 - Aug 10
Colorado Springs (COS) to Knoxville (TYS)
Knoxville (TYS) to Colorado Springs (COS)
Reviewed on Jul 2, 2026
Cumberland House Knoxville, Tapestry Collection by Hilton
Aug 7 - Aug 10
Colorado Springs (COS) to Knoxville (TYS)
Knoxville (TYS) to Colorado Springs (COS)
Reviewed on Jul 3, 2026
Hampton Inn & Suites Knoxville-Downtown
Aug 7 - Aug 10
Colorado Springs (COS) to Knoxville (TYS)
Knoxville (TYS) to Colorado Springs (COS)
Reviewed on Jun 30, 2026
More About Flying To Middlesboro from Colorado Springs
Route Information for Flights from Colorado Springs to Middlesboro
Origin Airport IATA Code | DEN |
|---|---|
Destination Airport IATA Code | TYS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Colorado Springs to Middlesboro
Rack up your savings with low-cost flights from Colorado Springs to Middlesboro with Orbitz On-the-Go. Orbitz On-the-Go offers mobile-only deals and cutting edge mobile tools to help you find bargain flights from Colorado Springs to Middlesboro.
Mobile-Only Deals on Colorado Springs to Middlesboro flights
Find guaranteed low prices on Colorado Springs to Middlesboro flights using Orbitz On-the-Go. You can book discount domestic flights from Colorado Springs to Middlesboro, and international tickets on Colorado Springs to Middlesboro flights using our mobile site and apps.
Free Alerts Are No Surprise
Not only will you find cheap tickets on flights from Colorado Springs to Middlesboro, but Orbitz free alerts will keep you up to speed on flight status, plus gate and baggage claim details. Receive instant updates via your choice of email, voice or text. Orbitz keeps you easily on task and on budget.
Share Itineraries on Flights from Colorado Springs to Middlesboro
Are you traveling for business, pleasure or a combination of both? Keep family, friends and business contacts posted on flight and gate info. Just use MyTrips for iPhone, Android and web phones like Blackberry and Windows.
Add Smiles to Your Miles with Sales and Deals on Colorado Springs to Middlesboro Flights
Travel planning is easy when you store your frequent flyer and loyalty program information on your Orbitz account. Then snag a low-fare air ticket on Colorado Springs to Middlesboro flights, and you’re done. No muss, no fuss. Your miles will fly by with Orbitz On-the-Go cutting edge mobile tools and guaranteed low prices.
- Flights from Colorado Springs
- Colorado Springs Airports
- Middlesboro Airports
- Airlines Operating
- Book on Expedia
Flights from Colorado Springs
- Colorado Springs to Dallas
- Colorado Springs to Phoenix
- Colorado Springs to Orlando
- Colorado Springs to Houston
- Colorado Springs to Los Angeles
- Colorado Springs to New York
- Colorado Springs to Chicago
- Colorado Springs to Kansas City
- Colorado Springs to Washington
- Colorado Springs to New Orleans
- Colorado Springs to Sacramento
- Colorado Springs to Detroit
- Colorado Springs to San Francisco
- Colorado Springs to Rome
- Colorado Springs to Amarillo
- Colorado Springs to Toronto
- Colorado Springs to Hartford
- Colorado Springs to London
- Colorado Springs to San Luis Obispo
- Colorado Springs to Abilene
Middlesboro Airports
More Destinations
- Flights from Houston to London
- Flights from London to London
- Flights from Minneapolis - St. Paul to London
- Flights from Nashville to London
- Flights from Seoul to London
- Flights from Frankfurt to London
- Flights from Delhi to London
- Flights from New Haven to London
- Flights from Panama City to London
- Flights from Birmingham to London
- Flights from Cape Town to London
- Flights from Tallahassee to London
- Flights from Mumbai to London
- Flights from Bangor to London
- Flights from San Salvador to London
- Flights from Wichita to London
- Flights from Covington to London
- Flights from Sioux Falls to London
- Flights from Rabat to London
- Flights from Hiroshima to London
- Flights from Lubbock to London
- Flights from Bozeman to London
- Flights from Duluth to Williamsburg
- Flights from Florence to Williamsburg
- Flights from Flint to Williamsburg
- Flights from Grand Junction to Williamsburg
- Flights from Killeen to Williamsburg
- Flights from Austin to Williamsburg
- Flights from Baltimore to Williamsburg
- Flights from Calgary to Williamsburg
- Flights from Dallas to Williamsburg
- Flights from Denver to Williamsburg
- Flights from Detroit to Williamsburg
- Flights from Lisbon District to Williamsburg
- Flights from Minneapolis - St. Paul to Williamsburg
- Flights from Phoenix to Williamsburg
- Flights from Salt Lake City to Williamsburg
- Flights from San Antonio to Williamsburg
- Flights from San Francisco to Williamsburg
- Flights from Vancouver to Williamsburg
- Flights from Washington to Williamsburg
- Flights from Venice to Williamsburg
- Flights from Charleston to Williamsburg
- Flights from Delhi to Williamsburg
- Flights from Shanghai to Williamsburg
- Flights from New Haven to Williamsburg
- Flights from Sacramento to Williamsburg
- Flights from Palm Springs to Williamsburg
- Flights from Lewiston to Williamsburg
- Flights from Montrose to Williamsburg
- Flights from Omaha to Williamsburg
- Flights from Albany to Williamsburg
- Flights from Eureka to Williamsburg
- Flights from Roanoke to Williamsburg
- Flights from St. George to Williamsburg
- Flights from Myrtle Beach to Williamsburg
- Flights from Pittsburgh to Williamsburg
- Flights from Toledo to Williamsburg
- Flights from Tulsa to Williamsburg
- Flights from Brunswick to Williamsburg
- Flights from Albuquerque to Williamsburg
- Flights from Buffalo to Williamsburg
- Flights from Medford to Williamsburg
- Flights from Little Rock to Williamsburg
- Flights from Oklahoma City to Williamsburg
- Flights from Allentown to Williamsburg
- Flights from Boise to Williamsburg
- Flights from Louisville to Williamsburg
- Flights from Binghamton to Williamsburg
- Flights from Asheville to Williamsburg
- Flights from Fayetteville to Williamsburg
- Flights from Cheyenne to Williamsburg
- Flights from Virginia to Williamsburg
- Flights from Corpus Christi to Williamsburg
- Flights from Austin to Richmond
- Flights from Minneapolis - St. Paul to Richmond
- Flights from Sydney to Richmond
- Flights from Washington to Richmond
- Flights from St. George to Richmond
- Flights from Brunswick to Richmond
- Flights from Cedar Rapids - Iowa City to Richmond
- Flights from Fresno to Richmond
- Flights from Louisville to Richmond
- Flights from Baton Rouge to Richmond
- Flights from Grand Rapids to Richmond
- Flights from Albany to Richmond
- Flights from Binghamton to Richmond
- Flights from Bangor to Richmond
- Flights from Tampico to Richmond
- Flights from Hyderabad to Richmond
- Flights from Guatemala City to Richmond
- Flights from Ithaca to Richmond
- Flights from Newport News to Richmond
- Flights from Bismarck to Richmond
- Flights from Bozeman to Richmond
- Flights from Dresden to Lake Cumberland
- Flights from Detroit to Pikeville
- Flights from St. Petersburg - Clearwater to Berea
- Flights from New York to General Burnside State Park
- Flights from Shanghai to Slade
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.