$135 Cheap flight deals from Myrtle Beach (MYR) to Waynesville (TYS)

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Airfares from $135 One Way, $263 Round Trip from Myrtle Beach to Waynesville

Prices starting at $263 for return flights and $135 for one-way flights to Waynesville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Mar 18 - Tue, Apr 7
MYR
Myrtle Beach
TYS
Knoxville
$263 Roundtrip, found 6 days ago
$263
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Mar 18 from Myrtle Beach to Knoxville, returning Tue, Apr 7, priced at $263 found 6 days ago
Wed, Apr 15 - Wed, May 6
MYR
Myrtle Beach
TYS
Knoxville
$264 Roundtrip, found 6 days ago
$264
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Apr 15 from Myrtle Beach to Knoxville, returning Wed, May 6, priced at $264 found 6 days ago
Mon, Mar 16 - Tue, Apr 7
MYR
Myrtle Beach
TYS
Knoxville
$282 Roundtrip, found 6 days ago
$282
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Mar 16 from Myrtle Beach to Knoxville, returning Tue, Apr 7, priced at $282 found 6 days ago
Wed, Apr 15 - Thu, May 7
MYR
Myrtle Beach
TYS
Knoxville
$283 Roundtrip, found 6 days ago
$283
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Apr 15 from Myrtle Beach to Knoxville, returning Thu, May 7, priced at $283 found 6 days ago
Wed, May 20 - Tue, Jun 9
MYR
Myrtle Beach
TYS
Knoxville
$286 Roundtrip, found 6 days ago
$286
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, May 20 from Myrtle Beach to Knoxville, returning Tue, Jun 9, priced at $286 found 6 days ago

Waynesville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bluegreen Vacations Blue Ridge Village, an Ascend Collection Resort
3.0-star property

Bluegreen Vacations Blue Ridge Village, an Ascend Collection Resort

9.2/10 Wonderful! (890 reviews)

Feb 22 - Feb 26

4 night stay

Myrtle Beach (MYR) to Asheville (AVL)

Delta • Non-stop roundtrip • Coach
Price was $765, price is now $666 per person
$666
per person
found 1 day ago
Great location, great mountain views, close to attractions and downtown. The room was nice and accommodating. Customer service needs improvements. When we walked in the lady at the front desk did not greet us or wait on us for a few minutes (nobody else was checking in). Finally, when we got help the lady didn’t know how to check over our online reservation and yelled to the manager in the back office to come out for insistance. We would come back, but please sharpen up the customer service skills.

Reviewed on Sep 8, 2024

The Lodge at Banner Elk
2.5-star property

The Lodge at Banner Elk

8.6/10 Excellent! (1,002 reviews)

Feb 22 - Feb 26

4 night stay

Myrtle Beach (MYR) to Asheville (AVL)

Delta • Non-stop roundtrip • Coach
Price was $822, price is now $701 per person
$701
per person
found 1 day ago
Clean rooms. Bathrooms are dated.

Reviewed on Dec 12, 2025

Chetola Resort
3.5-star property

Chetola Resort

9/10 Wonderful! (1,001 reviews)

Feb 22 - Feb 26

4 night stay

Myrtle Beach (MYR) to Asheville (AVL)

Delta • Non-stop roundtrip • Coach
Price was $880, price is now $768 per person
$768
per person
found 1 day ago
Very nice location, few things that i didn’t like. The room said Mountain View, it’s actually parking view; they were short on maids so they only made the beds, but never vacuum the floors or clean the glass of the shower; the heated pool was always chilling, my son and I always had to use the jacuzzi in order to have the proper water temperature.-

Reviewed on Jan 8, 2023

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More About Flying To Waynesville from Myrtle Beach

Route Information for Flights from Myrtle Beach to Waynesville

Origin Airport IATA Code
MYR
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Myrtle Beach to Waynesville

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.