$563 Cheap flight deals from Orlando (ORL) to Messina (REG)

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Airfares from $563 One Way, $1,020 Round Trip from Orlando to Messina

Prices starting at $1,020 for return flights and $563 for one-way flights to Messina were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Mar 11 - Sun, Mar 21
MCO
Orlando
REG
Metropolitan City of Reggio Calabria
$1,020 Roundtrip, found 3 days ago
$1,020
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Thu, Mar 11 from Orlando to Metropolitan City of Reggio Calabria, returning Sun, Mar 21, priced at $1,020 found 3 days ago
Thu, Mar 11 - Sun, Mar 21
MCO
Orlando
REG
Metropolitan City of Reggio Calabria
$1,043 Roundtrip, found 3 days ago
$1,043
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Thu, Mar 11 from Orlando to Metropolitan City of Reggio Calabria, returning Sun, Mar 21, priced at $1,043 found 3 days ago
Thu, Mar 11 - Sun, Mar 21
MCO
Orlando
REG
Metropolitan City of Reggio Calabria
$1,050 Roundtrip, found 3 days ago
$1,050
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Thu, Mar 11 from Orlando to Metropolitan City of Reggio Calabria, returning Sun, Mar 21, priced at $1,050 found 3 days ago
Mon, Nov 2 - Sat, Nov 7
MCO
Orlando
REG
Metropolitan City of Reggio Calabria
$1,056 Roundtrip, found 3 days ago
$1,056
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Mon, Nov 2 from Orlando to Metropolitan City of Reggio Calabria, returning Sat, Nov 7, priced at $1,056 found 3 days ago
Thu, Mar 11 - Sun, Mar 21
MCO
Orlando
REG
Metropolitan City of Reggio Calabria
$1,073 Roundtrip, found 3 days ago
$1,073
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Thu, Mar 11 from Orlando to Metropolitan City of Reggio Calabria, returning Sun, Mar 21, priced at $1,073 found 3 days ago

Messina economy flight packages

Price found within the past 48 hours. Click for updated prices.
UNA Hotels One Siracusa Wellness & SPA
4.0-star property

UNA Hotels One Siracusa Wellness & SPA

8.6/10 Excellent! (550 reviews)

Oct 27 - Nov 2

6 night stay

Orlando (MCO) to Catania (CTA)

United • Coach

Catania (CTA) to Orlando (MCO)

Swiss International Air Lines • Coach
Price was $1,955, price is now $1,613 per person
$1,613
per person
found 1 day ago
It’s a really beautiful hotel. Great staff, great food, AC works, beautiful spa. It’s in central place but not in the midst of all the chaos at the same time!

Reviewed on Jul 15, 2026

Re Dionisio Luxury Suites
3.0-star property

Re Dionisio Luxury Suites

8.8/10 Excellent! (58 reviews)

Oct 27 - Nov 2

6 night stay

Orlando (MCO) to Catania (CTA)

United • Coach

Catania (CTA) to Orlando (MCO)

Swiss International Air Lines • Coach
Price was $2,156, price is now $1,839 per person
$1,839
per person
found 1 day ago

Giuggiulena Villa
3.0-star property

Giuggiulena Villa

10/10 Exceptional! (131 reviews)

Oct 27 - Nov 2

6 night stay

Orlando (MCO) to Catania (CTA)

United • Coach

Catania (CTA) to Orlando (MCO)

Swiss International Air Lines • Coach
Price was $2,108, price is now $1,851 per person
$1,851
per person
found 1 day ago
Wow. We just spent 3 nights at Giuggiulena Villa and wish we had stayed here for our whole trip. Almost want to keep it a secret…! It’s a family-run, 8 room boutique hotel by the sea. Location; stunning, right on the sea, all rooms have a sea view; most have balconies overlooking the sea. The property has direct access to the sea (the coast is rocky all around this area). They have rock shoes provided, as well as mats to sit on, sun loungers and inflatables so you can spend your day in the crystal clear water. The hosts Sabrina and Claudia are so lovely and helpful. Excellent communication before the trip organising an airport transfer, booking a local restaurant for our first night’s dinner etc. The friendly family vibe makes you feel so welcome. Breakfast is simple but enough, fresh coffee, yoghurt, eggs, fruit and pastries eaten right by the sea on the terrace. One day they made us a small lunch (as we were busy drinking wine in the sea!) of bruschetta and local ‘spaghetti sandwiches’ which was amazing. They even baked the most delicious chocolate torte for my husband’s birthday. If your priority is being walking distance to Ortigia but with a prime seafront location, look no further. We adored this hotel and will be coming back.

Reviewed on Aug 25, 2026

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More About Flying To Messina from Orlando

Route Information for Flights from Orlando to Messina

Origin Airport IATA Code
ORL
Destination Airport IATA Code
REG
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Orlando to Messina

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.