Hotels in Southeast Missouri

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Mar 31 - Apr 1
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Check prices in Southeast Missouri for tonight, Mar 31 - Apr 1
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Top Rated Southeast Missouri Hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Apr 5 - Apr 6
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
50.35 mi from city center
$119 nightly
The price is $134 total per night
$134 total
Apr 6 - Apr 7
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and a gift shop.
Parking included
Free WiFi
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
$94 nightly
The price is $108 total per night
$108 total
Apr 5 - Apr 6
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.73 mi from city center
$94 nightly
The price is $106 total per night
$106 total
Apr 7 - Apr 8
Total with taxes and fees
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
$89 nightly
The price is $96 total per night
$96 total
Apr 5 - Apr 6
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a banquet hall.
Pool
Breakfast included
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
52.79 mi from city center
$97 nightly
The price is $110 total per night
$110 total
Apr 12 - Apr 13
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.36 mi from city center
$80 nightly
The price is $85 total per night
$85 total
Apr 5 - Apr 6
Total with taxes and fees
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
$58 nightly
The price is $66 total per night
$66 total
Apr 12 - Apr 13
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Breakfast included
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Free Cancellation
Reserve now, pay when you stay
29.15 mi from city center
$73 nightly
The price is $77 total per night
$77 total
Apr 1 - Apr 2
Total with taxes and fees
Guests staying at Motel 6 Poplar Bluff, MO enjoy free WiFi in public areas, laundry facilities, and a vending machine. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with tours/tickets and luggage storage.
Pet friendly
Parking included
Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!

Ste. Genevieve MO
41.04 mi from city center
$328 nightly
The price is $350 total per night
$350 total
Apr 2 - Apr 3
Total with taxes and fees
At this farm stay, guests have access to features like laundry facilities.
Laundry
The Farmstead Hotel

The Farmstead Hotel

2.5 out of 5
778 E 3rd St Caruthersville MO
Free Cancellation
Reserve now, pay when you stay
83.3 mi from city center
$94 nightly
The price is $107 total per night
$107 total
Apr 1 - Apr 2
Total with taxes and fees
Guests of The Farmstead Hotel enjoy features like a casino, free WiFi in public areas, and microwave in a common area. A stay here includes free parking. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a TV in a common area and an ATM.
Parking included
Free WiFi
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
Free Cancellation
47.02 mi from city center
$103 nightly
The price is $116 total per night
$116 total
Apr 12 - Apr 13
Total with taxes and fees
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Missouri hotels options

    Motel 6 Poplar Bluff, MO

    Motel 6 Poplar Bluff, MO

    4101 Highway 67 N Poplar Bluff MO
    $73 nightly
    The price is $77 total per night from Apr 1 to Apr 2
    $77 total
    Apr 1 - Apr 2
    Total with taxes and fees
    8/10 Very Good! (1,006 reviews)
    Super 8 by Wyndham Farmington

    Super 8 by Wyndham Farmington

    930 Valley Creek Dr Farmington MO
    $60 nightly
    The price is $68 total per night from Apr 6 to Apr 7
    $68 total
    Apr 6 - Apr 7
    Total with taxes and fees
    8/10 Very Good! (630 reviews)
    Super 8 by Wyndham Pevely

    Super 8 by Wyndham Pevely

    1711 Highway Z Pevely MO
    $79 nightly
    The price is $91 total per night from Apr 1 to Apr 2
    $91 total
    Apr 1 - Apr 2
    Total with taxes and fees
    5.6/10 (842 reviews)
    Pear Tree Inn Cape Girardeau West

    Pear Tree Inn Cape Girardeau West

    103 Cape West Pkwy Cape Girardeau MO
    $72 nightly
    The price is $81 total per night from Apr 5 to Apr 6
    $81 total
    Apr 5 - Apr 6
    Total with taxes and fees
    9/10 Wonderful! (1,004 reviews)
    Baymont Inn and Suites by Wyndham Farmington, MO

    Baymont Inn and Suites by Wyndham Farmington, MO

    1625 W Columbia St Farmington MO
    $58 nightly
    The price is $66 total per night from Apr 12 to Apr 13
    $66 total
    Apr 12 - Apr 13
    Total with taxes and fees
    8/10 Very Good! (1,009 reviews)
    Days Inn and Suites by Wyndham Sikeston

    Days Inn and Suites by Wyndham Sikeston

    220 S Interstate Dr Sikeston MO
    $68 nightly
    The price is $78 total per night from Apr 5 to Apr 6
    $78 total
    Apr 5 - Apr 6
    Total with taxes and fees
    7.2/10 Good! (1,003 reviews)

Southeast Missouri hotels essential information

Accommodation
630 hotels
Lowest Price
$66
Highest Price
$350
Popular hotels
Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, Drury Inn & Suites Sikeston, MO, Drury Inn & Suites Cape Girardeau, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Hampton Inn Sikeston, Drury Inn & Suites Jackson MO, Baymont Inn and Suites by Wyndham Farmington, MO, Motel 6 Poplar Bluff, MO, Silo Farm Haus- located in the heart of wine country!, The Farmstead Hotel, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Recent Reviews

The Riverview

The Riverview

5/5 Excellent
"This was a nice hotel, very reasonably priced, nice view, clean, and comfortable."
A verified traveler stayed at The Riverview
Posted 8 hours ago
The Riverview

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