Hotels in Southeast Missouri
Search over 657 hotels from $63
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Top Rated Southeast Missouri Hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
$96 nightly
The price is $108 total per night
$108 total
May 25 - May 26
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
$58 nightly
The price is $63 total per night
$63 total
Jun 7 - Jun 8
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Breakfast included

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
$111 nightly
The price is $128 total per night
$128 total
May 25 - May 26
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

The Riverview
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
50.35 mi from city center
$125 nightly
The price is $141 total per night
$141 total
May 18 - May 19
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and a TV in a common area.
Parking included
Free WiFi

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
52.79 mi from city center
$102 nightly
The price is $115 total per night
$115 total
May 31 - Jun 1
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
$93 nightly
The price is $100 total per night
$100 total
May 19 - May 20
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a vending machine.
Pool
Breakfast included

Fairfield Inn & Suites by Marriott Cape Girardeau
433 CAPE WEST CROSSINGS Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
47.14 mi from city center
$93 nightly
The price is $105 total per night
$105 total
May 28 - May 29
Total with taxes and fees
At Fairfield Inn & Suites by Marriott Cape Girardeau, guests have access to an indoor pool, free WiFi in public areas, and coffee in a common area. Free parking is available if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This hotel also has laundry facilities.
Pool
Breakfast included

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.36 mi from city center
$79 nightly
The price is $84 total per night
$84 total
May 25 - May 26
Total with taxes and fees
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84 Hayti MO
Free Cancellation
Reserve now, pay when you stay
78.5 mi from city center
$98 nightly
The price is $112 total per night
$112 total
May 31 - Jun 1
Total with taxes and fees
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.8 mi from city center
$72 nightly
The price is $81 total per night
$81 total
May 24 - May 25
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
Free Cancellation
47.19 mi from city center
$80 nightly
The price is $96 total per night
$96 total
May 25 - May 26
Total with taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly

Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
50.01 mi from city center
$125 nightly
The price is $142 total per night
$142 total
May 29 - May 30
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown features a 24-hour gym, free WiFi in public areas, and meeting rooms. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a terrace.
Parking included
Free WiFi
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check Southeast Missouri hotel room prices by star rating

4 Star Hotels
2 properties
Cheap Southeast Missouri hotels options

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
$75 nightly
The price is $84 total per night from May 17 to May 18
$84 total
May 17 - May 18
Total with taxes and fees
8/10 Very Good! (1,001 reviews)

Super 8 by Wyndham Farmington
930 Valley Creek Dr Farmington MO
$60 nightly
The price is $66 total per night from Jun 7 to Jun 8
$66 total
Jun 7 - Jun 8
Total with taxes and fees
8/10 Very Good! (642 reviews)

Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
$79 nightly
The price is $91 total per night from May 17 to May 18
$91 total
May 17 - May 18
Total with taxes and fees
5.6/10 (851 reviews)

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from May 24 to May 25
$81 total
May 24 - May 25
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
$58 nightly
The price is $63 total per night from Jun 7 to Jun 8
$63 total
Jun 7 - Jun 8
Total with taxes and fees
8/10 Very Good! (1,001 reviews)

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$65 nightly
The price is $74 total per night from May 17 to May 18
$74 total
May 17 - May 18
Total with taxes and fees
7.4/10 Good! (1,001 reviews)
Southeast Missouri hotels essential information
Accommodation | 657 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $142 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, Baymont Inn and Suites by Wyndham Farmington, MO, Drury Inn & Suites Sikeston, MO, The Riverview, Hampton Inn Sikeston, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Fairfield Inn & Suites by Marriott Cape Girardeau, Drury Inn & Suites Jackson MO, Drury Inn & Suites Hayti Caruthersville, Pear Tree Inn Cape Girardeau West, Candlewood Suites Cape Girardeau by IHG, Courtyard by Marriott Cape Girardeau Downtown |
Recent Reviews

The Riverview
5/5 Excellent
"The room and view were amazing!"
A verified traveler stayed at The Riverview
Posted 18 hours ago
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