Hotels in Southeast Missouri
Search over 670 hotels from $63
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Top Rated Southeast Missouri Hotels
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Aug 23 - Aug 24
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
$58 nightly
The price is $63 total per night
$63 total
Aug 23 - Aug 24
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Breakfast included
The Riverview
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
50.35 mi from city center
$114 nightly
The price is $129 total per night
$129 total
Aug 16 - Aug 17
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and a vending machine.
Parking included
Free WiFi
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
$94 nightly
The price is $108 total per night
$108 total
Aug 23 - Aug 24
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included
Baymont by Wyndham Festus
1200 W. Gannon Drive Festus MO
Free Cancellation
Reserve now, pay when you stay
68.15 mi from city center
$64 nightly
The price is $73 total per night
$73 total
Aug 25 - Aug 26
Total with taxes and fees
At Baymont by Wyndham Festus, guests enjoy an indoor pool, a gym, and free WiFi in public areas. There's free parking and a free beach shuttle. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Other amenities at this family-friendly hotel include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included
Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84 Hayti MO
Free Cancellation
Reserve now, pay when you stay
78.5 mi from city center
$98 nightly
The price is $112 total per night
$112 total
Aug 23 - Aug 24
Total with taxes and fees
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
$84 nightly
The price is $91 total per night
$91 total
Aug 17 - Aug 18
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a vending machine.
Pool
Breakfast included
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
Free Cancellation
47.02 mi from city center
$103 nightly
The price is $116 total per night
$116 total
Sep 13 - Sep 14
Total with taxes and fees
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
Free Cancellation
47.19 mi from city center
$83 nightly
The price is $99 total per night
$99 total
Aug 30 - Aug 31
Total with taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly
Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
Free Cancellation
Reserve now, pay when you stay
68.39 mi from city center
$62 nightly
The price is $71 total per night
$71 total
Sep 6 - Sep 7
Total with taxes and fees
At Comfort Inn Festus - St Louis South, guests have access to a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. Front-desk staff can answer questions 24/7, and assist with tours or tickets, dry cleaning/laundry, and securing valuables. Additional amenities include free newspapers, laundry facilities, and a gift shop.
Breakfast included
Parking included
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.8 mi from city center
$72 nightly
The price is $81 total per night
$81 total
Aug 23 - Aug 24
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly
The Farmstead Hotel
778 E 3rd St Caruthersville MO
Free Cancellation
Reserve now, pay when you stay
83.3 mi from city center
$95 nightly
The price is $108 total per night
$108 total
Aug 16 - Aug 17
Total with taxes and fees
Guests of The Farmstead Hotel enjoy features like a casino, free WiFi in public areas, and microwave in a common area. A stay here includes free parking. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a TV in a common area and an ATM.
Parking included
Free WiFi
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
How much is a Southeast Missouri hotel?
Check Southeast Missouri hotel room prices by star rating
4 Star Hotels
2 properties
Stay near popular Southeast Missouri attractions
Cheap Southeast Missouri hotels options
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
$72 nightly
The price is $81 total per night from Aug 16 to Aug 17
$81 total
Aug 16 - Aug 17
Total with taxes and fees
Super 8 by Wyndham Farmington
930 Valley Creek Dr Farmington MO
$60 nightly
The price is $65 total per night from Aug 23 to Aug 24
$65 total
Aug 23 - Aug 24
Total with taxes and fees
8/10 Very Good! (667 reviews)
Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
$67 nightly
The price is $78 total per night from Sep 13 to Sep 14
$78 total
Sep 13 - Sep 14
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Aug 23 to Aug 24
$81 total
Aug 23 - Aug 24
Total with taxes and fees
9/10 Wonderful! (1,002 reviews)
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
$58 nightly
The price is $63 total per night from Aug 23 to Aug 24
$63 total
Aug 23 - Aug 24
Total with taxes and fees
8/10 Very Good! (1,002 reviews)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$64 nightly
The price is $73 total per night from Sep 13 to Sep 14
$73 total
Sep 13 - Sep 14
Total with taxes and fees
7.2/10 Good! (1,001 reviews)
Southeast Missouri hotels essential information
Accommodation | 670 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $129 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, Baymont Inn and Suites by Wyndham Farmington, MO, The Riverview, Drury Inn & Suites Sikeston, MO, Baymont by Wyndham Festus, Drury Inn & Suites Hayti Caruthersville, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Candlewood Suites Cape Girardeau by IHG, Comfort Inn Festus - St Louis South, Pear Tree Inn Cape Girardeau West, The Farmstead Hotel |
Recent Reviews
Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"Best hotel so far great customer service great breakfast awesome kickback very nice and clean love the roof top"
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 12 hours ago
The Riverview
5/5 Excellent
"Very well kept"
A verified traveler stayed at The Riverview
Posted 2 days ago
More to Explore
- Wappapello Hotels
- Cabin Rentals in Belleview
- Belleview Hotels
- 2 Star Hotels in Central Fredericktown
- Caledonia Hotels
- Cabin Rentals in Piedmont
- Condo Rentals in Piedmont
- Pet Friendly Hotels in Piedmont
- Piedmont Hotels
- Lodges in Piedmont
- Motels in Piedmont
- Lodges in Greenville
- Rv Parks in Greenville
- Resorts in Greenville
- 3 Star Hotels in Ironton
- B&B in Ironton
- Cottages in Ironton
- Cheap Hotels in Ironton
- Historic Hotels in Ironton
- Hotels with Bar in Ironton
- Ironton Hotels
- Motels in Ironton
- Vacation Homes in Ironton
- B&B in Doe Run
- Cabin Rentals in Doe Run
- Cottages in Doe Run
- Hotels near Crown Valley Winery
- Bismarck Hotels
- 3 Star Hotels in Fredericktown
- 5 Star Hotels in Fredericktown
- B&B in Fredericktown
- Cabin Rentals in Fredericktown
- Condo Rentals in Fredericktown
- Cottages in Fredericktown
- Pet Friendly Hotels in Fredericktown
- Fredericktown Hotels
- Motels in Fredericktown
- 3 Star Hotels in Arcadia
- 4 Star Hotels in Arcadia
- Cabin Rentals in Arcadia
- Cottages in Arcadia
- Hotels with Pool in Arcadia
- Motels in Arcadia
- Mill Spring Hotels
- Motels in Mill Spring
- Hotels near Johnson's Shut-ins State Park
- Hotels near Taum Sauk Mountain State Park
- Hotels near Elephant Rocks State Park
- Hotels near Fort Davidson State Historic Site
- Ellington Hotels
- Advance Hotels
- Sturdivant Hotels
- Park Hills Hotels
- Cottages in Middle Brook
- Cobalt Hotels
- Black Hotels
- Farmington Hotels
- Hotels near Twin Oaks Vineyard & Winery
- B&B in Pilot Knob
- Kid Friendly Hotels in Pilot Knob
- Hotels with Pool in Pilot Knob
- Hotels with Air Conditioning in Pilot Knob
- Pilot Knob Hotels
- Hotels near Millstream Gardens Conservation Area
- 4 Star Hotels in Lesterville
- Apartments in Lesterville
- Cabin Rentals in Lesterville
- Cottages in Lesterville
- Kid Friendly Hotels in Lesterville
- Hotels with Pool in Lesterville
- Pet Friendly Hotels in Lesterville
- Lodges in Lesterville
- Vacation Homes in Lesterville
- Hotels near St. Joe State Park
- Hotels near Crown Pointe Golf Club
- Hotels near K Bridge Recreation Area
- Apartments in Arcadia Valley Station
- Cabin Rentals in Arcadia Valley Station
- B&B in Annapolis
- Cabin Rentals in Annapolis
- Vacation Homes in Annapolis
- Hotels near Lake Wappapello
- Centerville Hotels
- Cabin Rentals in Marble Hill
- Marble Hill Hotels
- Motels in Marble Hill
- Des Arc Hotels
