Hotels in Southeast Missouri
Search over 623 hotels from $51
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Top Rated Southeast Missouri Hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Feb 17 - Feb 18
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub

The Riverview
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
50.35 mi from city center
$106 nightly
The price is $120 total per night
$120 total
Feb 16 - Feb 17
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and a vending machine.
Parking included
Free WiFi

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
$54 nightly
The price is $62 total per night
$62 total
Feb 19 - Feb 20
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
$84 nightly
The price is $91 total per night
$91 total
Feb 16 - Feb 17
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a vending machine.
Pool
Breakfast included

Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.73 mi from city center
$90 nightly
The price is $102 total per night
$102 total
Feb 17 - Feb 18
Total with taxes and fees
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
$94 nightly
The price is $108 total per night
$108 total
Feb 17 - Feb 18
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
Free Cancellation
47.19 mi from city center
$80 nightly
The price is $96 total per night
$96 total
Feb 22 - Feb 23
Total with taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
51.43 mi from city center
$99 nightly
The price is $106 total per night
$106 total
Feb 17 - Feb 18
Total with taxes and fees
At Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy, guests have access to features like express check-out. You can put free parking to good use if you drive.
Kitchen
Pet friendly

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.8 mi from city center
$72 nightly
The price is $81 total per night
$81 total
Feb 19 - Feb 20
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
52.79 mi from city center
$95 nightly
The price is $108 total per night
$108 total
Feb 28 - Mar 1
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Free Cancellation
Reserve now, pay when you stay
29.15 mi from city center
$49 nightly
The price is $51 total per night
$51 total
Feb 15 - Feb 16
Total with taxes and fees
Guests staying at Motel 6 Poplar Bluff, MO enjoy free WiFi in public areas, laundry facilities, and a vending machine. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with tours/tickets and luggage storage.
Pet friendly
Parking included
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check Southeast Missouri hotel room prices by star rating

4 Star Hotels
2 properties
Cheap Southeast Missouri hotels options

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
$49 nightly
The price is $51 total per night from Feb 15 to Feb 16
$51 total
Feb 15 - Feb 16
Total with taxes and fees
7.8/10 Good! (1,000 reviews)

Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
9.2/10 Wonderful! (1,001 reviews)

Super 8 by Wyndham Farmington
930 Valley Creek Dr Farmington MO
$54 nightly
The price is $61 total per night from Feb 15 to Feb 16
$61 total
Feb 15 - Feb 16
Total with taxes and fees
8/10 Very Good! (623 reviews)

Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
$74 nightly
The price is $85 total per night from Feb 27 to Feb 28
$85 total
Feb 27 - Feb 28
Total with taxes and fees
5.6/10 (831 reviews)

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Feb 19 to Feb 20
$81 total
Feb 19 - Feb 20
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
$54 nightly
The price is $62 total per night from Feb 19 to Feb 20
$62 total
Feb 19 - Feb 20
Total with taxes and fees
7.8/10 Good! (1,001 reviews)
Southeast Missouri hotels essential information
Accommodation | 623 hotels |
|---|---|
Lowest Price | $51 |
Highest Price | $351 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, Baymont Inn and Suites by Wyndham Farmington, MO, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Drury Inn & Suites Cape Girardeau, Drury Inn & Suites Sikeston, MO, Candlewood Suites Cape Girardeau by IHG, Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy, Pear Tree Inn Cape Girardeau West, Hampton Inn Sikeston, Motel 6 Poplar Bluff, MO, Silo Farm Haus- located in the heart of wine country! |
Recent Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
5/5 Excellent
"Yes .. staff was outstanding as was the cleanliness of the room"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Posted 6 days ago
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