Spa Resorts in South San Diego, CA
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Featured South San Diego Spa Resorts & Hotels

Pier South Resort, Autograph Collection by Marriott
800 Seacoast Dr Imperial Beach CA
Free Cancellation
Reserve now, pay when you stay
$169 nightly
The price is $192 total per night
$192 total
Dec 20 - Dec 21
Total with taxes and fees
Guests staying at Pier South Resort, Autograph Collection by Marriott enjoy access to a full-service spa, a gym, and free WiFi in public areas. Valet parking is available for USD 30 per day. The front desk is staffed 24/7 to help with tours or tickets, securing valuables, and dry cleaning/laundry. Other amenities at this beach hotel include meeting rooms, conference space, and a 24-hour business center.
Spa
Free WiFi

Hotel Palmeras Chula Vista
230 Broadway Chula Vista CA
Free Cancellation
Reserve now, pay when you stay
$62 nightly
The price is $68 total per night
$68 total
Dec 21 - Dec 22
Total with taxes and fees
Hotel Palmeras Chula Vista features free WiFi in public areas and a vending machine. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Parking included
Free WiFi

Best Western Americana Inn
815 W San Ysidro Boulevard San Ysidro CA
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $125 total per night
$125 total
Dec 25 - Dec 26
Total with taxes and fees
Best Western Americana Inn features an outdoor pool, free WiFi in public areas, and conference space. If you plan to drive, free parking is available. Multilingual staff at the 24-hour front desk can assist with luggage storage, tours or tickets, and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Holiday Inn Express San Diego South - Chula Vista by IHG
632 E Street Chula Vista CA
Free Cancellation
$114 nightly
The price is $125 total per night
$125 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Holiday Inn Express San Diego South - Chula Vista by IHG, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a hot tub, conference space, and a business center.
Pool
Hot Tub

Chula Vista Inn
946 Broadway Chula Vista CA
Free Cancellation
Reserve now, pay when you stay
$81 nightly
The price is $89 total per night
$89 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Chula Vista Inn enjoy access to free WiFi in public areas, coffee in a common area, and a meeting room. A stay here includes free parking. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include laundry facilities, a banquet hall, and a vending machine.
Parking included
Free WiFi

Comfort Inn Chula Vista San Diego South
91 Bonita Rd Chula Vista CA
Free Cancellation
Reserve now, pay when you stay
$97 nightly
The price is $107 total per night
$107 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Comfort Inn Chula Vista San Diego South, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a hot tub, a business center, and coffee/tea in a common area.
Pool
Hot Tub

Quality Suites San Diego Otay Mesa
2351 Otay Center Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
$109 nightly
The price is $124 total per night
$124 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Suites San Diego Otay Mesa offers a gym, free WiFi in public areas, and a hot tub. If you drive, put free parking to good use. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include conference space, a 24-hour business center, and express check-out.
Hot Tub
Breakfast included

Days Inn by Wyndham Chula Vista/San Diego
394 Broadway Chula Vista CA
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $74 total per night
$74 total
Dec 21 - Dec 22
Total with taxes and fees
Days Inn by Wyndham Chula Vista/San Diego offers an outdoor pool, free WiFi in public areas, and a hot tub. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations. Additional amenities include coffee/tea in a common area, laundry facilities, and a banquet hall.
Pool
Hot Tub
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See all available properties in South San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South San Diego hotels essential information
Accommodation | 7,773 hotels |
|---|---|
Lowest Price | $68 |
Highest Price | $192 |
Popular hotels | Pier South Resort, Autograph Collection by Marriott, Hotel Palmeras Chula Vista, Best Western Americana Inn, Holiday Inn Express San Diego South - Chula Vista by IHG, Chula Vista Inn, Comfort Inn Chula Vista San Diego South, Quality Suites San Diego Otay Mesa, Days Inn by Wyndham Chula Vista/San Diego |
Recent Spa Resorts & Hotels Reviews

Lafayette Hotel & Club
5/5 Excellent
"My favorite hotel in San Diego. Staff is always helpful, kind and professional.
The rooms are comfortable, clean, eclectic and possibly the best minibar selection of top shelf products anywhere.
The property invites you to discover and play and socialize. The bar and food programs are superb. "
A verified traveler stayed at Lafayette Hotel & Club
Posted 1 day ago
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