Compare Santee Vacation Rentals

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Santee Rentals

Waterfront Lake Marion Escape – Ground floor on End Unit w/ Gazebo • Off I-95

Waterfront Lake Marion Escape – Ground floor on End Unit w/ Gazebo • Off I-95

Santee SC
1.37 mi from city center
This condo features an outdoor pool and laundry facilities.
Pool
Kitchen
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Santee SC
1.36 mi from city center
$419 nightly
The price is $465 total per night
$465 total
Nov 3 - Nov 4
Total with taxes and fees
At this condo, guests have access to features like laundry facilities. This golf condo building also has barbecue grills.
Pool
Kitchen
CatDaddy Cabin - Lake Marion Cabin in Santee - lake view, fire pit, boat parking

CatDaddy Cabin - Lake Marion Cabin in Santee - lake view, fire pit, boat parking

Santee SC
1.86 mi from city center
Guests staying at this cabin have access to laundry facilities, a garden, and barbecue grills.
Kitchen
Washer
Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation

Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation

Santee SC
1.04 mi from city center
At this condo, guests have access to features like laundry facilities. This smoke-free condo building also has barbecue grills.
Kitchen
Washer
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee SC
1.77 mi from city center
$267 nightly
The price is $297 total per night
$297 total
Nov 3 - Nov 4
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Kitchen
Washer
Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss

Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss

Santee SC
1 mi from city center
At this condo, guests have access to features like laundry facilities.
Kitchen
Washer
Beautiful, ground level 3-bedroom condo with pool on scenic Lake Marion

Beautiful, ground level 3-bedroom condo with pool on scenic Lake Marion

Santee SC
1.31 mi from city center
At this condo, guests have access to an outdoor pool, laundry facilities, and a garden.
Pool
Kitchen
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive Santee SC
0.16 mi from city center
Guests staying at Wyndham Vacation Resorts Lake Marion enjoy features like an outdoor pool. Free parking is included with your stay.
Pool
Kitchen
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.

Summerton SC
Free Cancellation
3.44 mi from city center
$141 nightly
The price is $157 total per night
$157 total
Nov 3 - Nov 4
Total with taxes and fees
This cabin is a smoke-free cabin.
Kitchen
Pet friendly
Bells Marina & Resort

Bells Marina & Resort

2.5 out of 5
12907 Old Number Six Hwy Eutawville SC
11.52 mi from city center
$74 nightly
The price is $82 total per night
$82 total
Nov 3 - Nov 4
Total with taxes and fees
Renovated in 2025, Bells Marina & Resort offers a marina, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk has multilingual staff that can answer questions about the accommodations, services, and more. Other amenities at this golf aparthotel include conference space, laundry facilities, and a vending machine.
Pet friendly
Parking included
Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property

Holly Hill SC
12.98 mi from city center
$169 nightly
The price is $187 total per night
$187 total
Nov 5 - Nov 6
Total with taxes and fees
At this cottage, guests have access to features like laundry facilities.
Kitchen
Washer
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

Summerton SC
14.1 mi from city center
Guests staying at this vacation home have access to laundry facilities, a garden, and barbecue grills.
Kitchen
Washer
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santee Large Group Rentals

How to Book Vacation Rentals in Santee



🏠 What is the best price for Santee vacation rentals?

Santee vacation rentals range in price, starting at $82 per night.


🏠 What types of vacation rentals in Santee can I rent?

Orbitz offers a wide range of Santee rentals so you can plan the perfect vacation. Whether you're on a budget or looking for luxury, our rentals include spots for families, couples, activities, leisure, summer, winter, and more. Explore unique property types available such as cabins, cottages, private vacation homes, and Santee condo rentals.


🏠 Is it free to cancel my Santee vacation rental with Orbitz?

Most vacation rentals are free to cancel when you do so before the cancellation deadline. However, cancellation policies vary by property. Non-refundable bookings will not receive a refund. We recommend booking with free cancellation in case your plans change.


🏠 How do I find the best deals to rent a Santee vacation rental with Orbitz?

There are many different options for finding the best deal to suit your needs. Choose exclusive offers on rentals in various locations in Santee. You can filter by price range, guest rating, property type, neighborhood, and more to customize your search and view the best deals for you.


🏠 How can I cancel my vacation rental booking through Orbitz?

Change of plans? We get it. You can cancel most vacation rentals bookings by getting in touch with the property manager. Sign in to your account and navigate to ‘My Trips’. Choose ‘Itinerary’ to view the property’s contact details. For questions and concerns, you can always visit our customer service portal.


🏠 What are the advantages of booking a vacation rental in Santee?

Vacation rentals are your home away from home, offering a different kind of experience than traditional hotels. They’re often the best option if you're looking for more space, more privacy, and a place to make your own. Find homes for all kinds of stays with Orbitz. Plan group vacations with short-term rentals or choose from our Santee apartments and enjoy an extended stay.


🏠 Why should I book my vacation rental with Orbitz in Santee?

Orbitz offers incredible deals and offers on a large selection of vacation rentals as your one-stop-shop for travel. You’ll get rewards back with every booking, and when you book your stay along with a rental car, flight, or activity, our Santee package deals will get you even more savings.