Santee Luxury Hotels
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Featured Santee Luxury Hotels

Red Roof Inn Santee
9091 Old Hwy 6, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $70 total per night
$70 total
Nov 3 - Nov 4
Total with taxes and fees
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a vending machine.
Breakfast included
Pet friendly

Comfort Inn & Suites Santee
221 Britain St, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $116 total per night
$116 total
Nov 16 - Nov 17
Total with taxes and fees
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Baymont by Wyndham Santee
249 Britain Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $83 total per night
$83 total
Nov 2 - Nov 3
Total with taxes and fees
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.

Ramada by Wyndham Santee I-95
123 Mall Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $79 total per night
$79 total
Nov 6 - Nov 7
Total with taxes and fees
Guests of Ramada by Wyndham Santee I-95 have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking, and an airport shuttle (available 24 hours) for USD 80 per room roundtrip. The 24-hour front desk has staff always at the ready. Other amenities at this golf hotel include meeting rooms, a conference center, and a 24-hour business center.
Pool
Pet friendly

Econo Lodge
9112 Old 6 Highway, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $70 total per night
$70 total
Nov 17 - Nov 18
Total with taxes and fees
Econo Lodge features free WiFi in public areas and barbecue grills. There's free parking if you drive. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. This hotel also has a garden.
Pet friendly
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santee hotels essential information
Accommodation | 291 hotels |
|---|---|
Lowest Price | $70 |
Highest Price | $116 |
Popular hotels | Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge |
Recent Luxury Hotels Reviews

Comfort Inn & Suites Santee
5/5 Excellent
"I like the smell"
A verified traveler stayed at Comfort Inn & Suites Santee
Posted 3 days ago
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