Santee Luxury Hotels
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Featured Santee Luxury Hotels

Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
The price is $70 total per night
$70 total
per night
May 17 - May 18
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This hotel also has a vending machine.
Breakfast included
Pet friendly

Comfort Inn & Suites Santee
221 Britain St Santee SC
Free Cancellation
The price is $126 total per night
$126 total
per night
May 27 - May 28
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Baymont by Wyndham Santee
249 Britain Street Santee SC
Free Cancellation
Reserve now, pay when you stay
The price is $83 total per night
$83 total
per night
May 13 - May 14
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.
Breakfast included
Pet friendly

Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
Free Cancellation
Reserve now, pay when you stay
The price is $82 total per night
$82 total
per night
May 31 - Jun 1
Ramada by Wyndham Santee I-95 features a nightclub, karaoke, and an outdoor pool. There's free parking, and an airport shuttle (available 24 hours) for USD 80 per room roundtrip. The front desk is staffed 24/7 to help with dry cleaning or laundry, and answer any questions about the accommodations. Other amenities at this golf hotel include a 24-hour gym, free WiFi in public areas, and meeting rooms.
Pool
Pet friendly

Econo Lodge Santee
9112 Old 6 Highway Santee SC
Free Cancellation
Reserve now, pay when you stay
The price is $84 total per night
$84 total
per night
May 25 - May 26
Econo Lodge Santee features free WiFi in public areas and barbecue grills. There's free parking if you drive. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. This hotel also has a garden.
Pet friendly
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santee hotels essential information
Accommodation | 308 hotels |
|---|---|
Lowest Price | $70 |
Highest Price | $126 |
Popular hotels | Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge Santee |
Recent Luxury Hotels Reviews

Baymont by Wyndham Santee
4/5 Good
"I was greeted like I was a friend. She asked me about my reservation and offered an alternative on the first floor with parking right outside the room. As a 73 year old solo traveler, considerations like that are gifts from heaven. "
A verified traveler stayed at Baymont by Wyndham Santee
Posted 3 hours ago
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