$142 Cheap flights to Santa Cruz
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Top places to visit in Santa Cruz
Cheap flights to Santa Cruz from $142 One Way, $270 Round Trip
$270 return flights and $142 one-way flights to Santa Cruz were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| GYE | Puerto Baquerizo Moreno | October 23 to October 26 | $293 |
| GYE | Santa Rosa | October 24 to October 28 | $296 |
| UIO | Santa Rosa | October 23 to October 25 | $297 |
| UIO | Puerto Baquerizo Moreno | October 25 to October 27 | $331 |
| LIM | Santa Rosa | October 25 to October 28 | $630 |
| JFK | Puerto Baquerizo Moreno | October 25 to November 1 | $713 |
| MIA | Puerto Baquerizo Moreno | October 23 to October 28 | $720 |
| JFK | Santa Rosa | October 23 to October 26 | $734 |
| LIM | Puerto Baquerizo Moreno | October 25 to October 28 | $852 |
| MIA | Santa Rosa | October 23 to October 28 | $882 |
| YYZ | Santa Rosa | October 24 to November 6 | $894 |
| LAX | Santa Rosa | October 25 to October 29 | $1,190 |
Find The Perfect Hotel For After Your Flight
Score Epic Santa Cruz Accommodation Deals
Hotel Fiesta
"We had a great stay. Quiet and close to everything"
Reviewed on Oct 13, 2026
Hotel el descanso del Guia
"All the staff were wonderful and very helpful. The breakfast was great and offered a good amount of food. Eric was the best and helped us navigate getting around the island. I would definitely stay at this hotel again."
Reviewed on Oct 16, 2026
Maidith Galapagos Inn
Finch Bay Galapagos Hotel
"המלון הכי טוב בגלאפגוס רמה גבוהה מאוד שירות מדהים קצת יקר אבל שווה את המחיר מומלץ מאוד"
Reviewed on Oct 14, 2026
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Santa Cruz
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Mix and Match
At Orbitz, we turned a great idea from the world of fashion into another way for you to save money. When you shop our low cost tickets on flights to any destination, don’t be afraid to mix and match different airlines for maximum savings on your Santa Cruz flights air ticket. Save more on air travel every day in every way at Orbitz.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.