$114 Cheap flights to Florence County

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Top places to visit in Florence County

A calm lake surrounded by trees with autumn foliage.
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Florence

Florence
A sunset over a forested landscape with a river and a parking lot.
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Lake City

Lake City

Cheap flights to Florence County from $114 One Way, $140 Round Trip

$140 return flights and $114 one-way flights to Florence County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jan 19 - Fri, Jan 22
RSW
Fort Myers
MYR
Myrtle Beach
$256 Roundtrip, found 5 days ago
$256
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 19 from Fort Myers to Myrtle Beach, returning Fri, Jan 22, priced at $256 found 5 days ago
Tue, Jan 19 - Fri, Jan 22
RSW
Fort Myers
MYR
Myrtle Beach
$256 Roundtrip, found 5 days ago
$256
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Jan 19 from Fort Myers to Myrtle Beach, returning Fri, Jan 22, priced at $256 found 5 days ago
Tue, Jan 19 - Fri, Jan 22
RSW
Fort Myers
MYR
Myrtle Beach
$262 Roundtrip, found 5 days ago
$262
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Jan 19 from Fort Myers to Myrtle Beach, returning Fri, Jan 22, priced at $262 found 5 days ago
Tue, Jan 19 - Fri, Jan 22
RSW
Fort Myers
MYR
Myrtle Beach
$277 Roundtrip, found 5 days ago
$277
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 19 from Fort Myers to Myrtle Beach, returning Fri, Jan 22, priced at $277 found 5 days ago
Tue, Jan 19 - Fri, Jan 22
RSW
Fort Myers
MYR
Myrtle Beach
$285 Roundtrip, found 5 days ago
$285
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 19 from Fort Myers to Myrtle Beach, returning Fri, Jan 22, priced at $285 found 5 days ago
Tue, Jan 19 - Fri, Jan 22
RSW
Fort Myers
MYR
Myrtle Beach
$300 Roundtrip, found 5 days ago
$300
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 19 from Fort Myers to Myrtle Beach, returning Fri, Jan 22, priced at $300 found 5 days ago

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
FLLMyrtle BeachOctober 30 to November 16$140
SWFMyrtle BeachNovember 1 to November 5$167
TPAMyrtle BeachNovember 1 to November 18$180
ALBMyrtle BeachOctober 30 to November 2$288
LGAMyrtle BeachNovember 1 to November 7$435
BOSMyrtle BeachOctober 31 to November 2$454
EWRMyrtle BeachOctober 30 to November 1$476
DFWMyrtle BeachOctober 31 to November 2$542
DENMyrtle BeachOctober 31 to November 1$581
EWRFlorenceOctober 31 to November 2$613
EWRFlorenceOctober 31 to November 2$613
MSPMyrtle BeachOctober 31 to November 3$689
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Florence County Accommodation Deals

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Nov 8 to Nov 9
$100 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Opens in a new windowPark Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Oct 27 to Oct 28
$68 total
Oct 27 - Oct 28
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,758 reviews)
"Quiet clean and inexpensive stay, especially relative to neighboring locations"

Reviewed on Oct 26, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundable
$101 nightly
The price is $113 total per night from Nov 15 to Nov 16
$113 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,378 reviews)
"The Staff was Great and helpful. Only thing a little uncomfortable was the water in the sink and shower was barely warm."

Reviewed on Oct 25, 2026

Opens in a new windowComfort Inn & Suites Florence Center Area
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Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Nov 3 to Nov 4
$112 total
Nov 3 - Nov 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Opens in a new windowHyatt Place Florence Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Florence County

Why search for low cost fares on your flights to Florence County when Orbitz offers the guaranteed lowest prices on foreign and domestic flights? When you travel with Orbitz you can benefit from:

Bargain Flights to Florence County

Orbitz offers massive discounts and substantial last-minute savings on your Florence County flights. Orbitz ensures that you can find, plan and reserve your flights any destination with ease, all while enjoying the guaranteed lowest prices available anywhere.

Cutting-Edge Mobile Tools to Keep You In The Know

Orbitz sends you free alerts and updates on your Florence County flight wherever you are in the world. Once you have downloaded the free app for your iPhone, Android, or iPad, you can review or alter any travel plans that you have made or even book a future flight for business or pleasure. If you need to reserve a hotel room when booking your flight, you will find exclusive deals on our mobile site.

Frequent Flyer Program Enrolment

Orbitz finds you the lowest fares, but you can still add your miles to your frequent flyer program to earn miles or points on selected flights to Florence County. When making your booking, reference your frequent flyer number to receive discounts in the future.

Outstanding Customer Service

Orbitz values your business and wants to ensure that all of your flights are as easy as possible to book. If you have booked a flight to Florence County but need to cancel it, you may be able to do so online. If you have any questions or need help, the dedicated Orbitz customer service team is always standing by.

Frequently asked questions

What is the best airport to fly to in Florence County?
There's one main entry point for this region — Florence Regional Airport (FLO). Book your flights to this popular gateway and see all that Florence County has to offer.
How much is a flight to Florence County?
Round-trip prices dropped as low as $140 this week to Florence County, and reached a high of $689. Passengers flying out of Fort Myers (RSW) managed to land one-way flights from just $114.
How to book the cheapest flight to Florence County?
Snapping up cheap flights to Florence County is as simple as booking your ticket with Orbitz. But if you'd love to make sure you're nabbing the best flight deals around, here are a few tips worth following:

  • Depending on your place of departure, choose the 'Nearby airports' function (located under the departure and arrival options). At times, other departure points will have cheaper fares.
  • Also, click on the 'Show flexible dates' link to view the prices for days around your chosen departure. You may be able to pick up cheaper flight deals if you're flexible with your schedule.
  • You can also use the 'Show options' link to filter results for your preferred carrier, seating class, nonstop flights and refundable flights. Under 'Sort & Filter' to the left, you can even choose the time of day you want to fly.
  • Once you've sorted out your travel dates, don't delay booking. Prices generally increase as the departure date nears.
  • Think about bundling your hotels, flights and car rental into an Orbitz package — the more you book, the more you save.
  • Flying during busier seasons means steep airfares. If possible, plan your trip outside of popular periods, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Florence County?
Generally speaking, January is the cheapest time to purchase your plane ticket. This is closely followed by February and August. Bear this in mind while you search for a cheap flight to Florence County.
What day of the week is the cheapest to book a flight to Florence County?
If you're after inexpensive fares to Florence County, the best days to make a booking are Tuesdays, Wednesdays and Saturdays. With Orbitz (and some good timing!), an unbeatable flight deal will be all yours.
What is the cheapest day of the week to fly to Florence County?
Based on Orbitz data from 2020, Monday tends to be the best day to nab cheap flights to Florence County. Tuesday also offers budget-friendly airfares, whereas Saturday has the most expensive ticket prices. Although flying out at the weekend can be more suitable, you'll have more money in your pocket to play with if you jet out early in the week.
What is the cheapest month to fly to Florence County?
If you're flexible with your travel dates, consider leaving during August. Orbitz data shows that this is generally the best month to take off if you're looking for cheap flights to Florence County. As you would imagine, fares get pricier in June and flights book out quickly.
Which airlines allow free cancellation?
Life changes, and we believe your ticket should be able to do the same. That's why Orbitz makes it a snap to search for airlines with free cancellation and no change fees. Just enter your departure and arrival points and then select "Filter by flexible change policies." How's that for peace of mind?
What do I need for the flight to Florence County?
Whether you're accustomed to flying or you're new to the skies, it's always great to be prepared when you travel. Here are several tips and things to take into consideration:

  • Make sure you've packed your travel documents and identification. For overseas trips, you'll need your passport. When booking your seats, always use the same name, birth date and gender as listed on your current ID.
  • Pack your carry-on bag with snacks and things to keep you busy and watch time whiz by on this medium-haul flight. Wherever possible, hop on the airport's Wi-Fi and transfer your favorite playlist or podcast to your phone or tablet before take off.
  • Never mind what the season is, airplane cabins are often quite cold. Bring a sweater with you on your journey to stay cozy and warm.

How do I get cheap first-class/business deals to Florence County?
There are ways of booking first or business-class airfares to Florence County that won't burn through your budget. Pick up a seat at the front of the plane for less with these useful tips:

  • Be flexible with your travel dates and wait for huge sales on business or first-class airfares.
  • Budget airlines offer business-class seating at a fraction of the usual price. Ditch the full-service carriers and fly with one these cheaper options.
  • Make a bid for an upgrade. Some carriers hold online auctions that let you offer a price for a seat at the front of the plane. You may also be able to upgrade with points earned through a loyalty program.

What is the best time to go to Florence County?
If you'd like to experience Florence County in the peak season, March, April and July are the top months to visit. June 20 marks the onset of summer in the Northern Hemisphere and is an awesome time to travel if you love being outside. During this time of the year, average daily temperatures generally range from 70 ºF to 90 ºF.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.