Hampton Inn & Suites St. Louis/South I-55

2.5 star property
Hotel in St. Louis with free breakfast and a fitness center

Choose dates to view prices

Photo gallery for Hampton Inn & Suites St. Louis/South I-55

Two Queen Beds, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board
Indoor pool
Lobby
Exterior
Reception

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Housekeeping
  • Laundry
  • Parking included

Explore the area

View in a map
4200 Midamerica Lane, St. Louis, MO, 63129
  • Place, Mercy Hospital South
    ‪4 min drive‬
  • Place, River City Casino
    ‪10 min drive‬
  • Place, Grant's Farm
    ‪13 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪30 min drive‬

Room options

Room

9.8 out of 10
Exceptional
(34 reviews)
  • 460 sq ft
  • Sleeps 4
  • 2 Queen Beds

Room

9.6 out of 10
Exceptional
(14 reviews)
  • 460 sq ft
  • Sleeps 2
  • 1 King Bed

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(26 reviews)
  • 460 sq ft
  • Sleeps 4
  • 2 Queen Beds

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(18 reviews)
  • 460 sq ft
  • Sleeps 2
  • 1 King Bed

Studio, Accessible, Non Smoking

9.2 out of 10
Wonderful
(5 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed

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About the neighborhood

St. Louis

Located within a leisurely stroll of Barnes Jewish South Campus, Hampton Inn & Suites St. Louis/South I-55 is within a few miles (5 km) of St Anthony's. This 92-room hotel welcomes guests with conveniences like free breakfast, an indoor pool, and free in-room WiFi.

What's nearby

  • Barnes Jewish South Campus - 5 min walk - 0.3 miles
  • Mercy Hospital South - 4 min drive - 4.6 miles
  • River City Casino - 10 min drive - 8.0 miles
  • Magic House - St. Louis Children's Museum - 12 min drive - 10.9 miles
  • Grant's Farm - 13 min drive - 9.7 miles

Getting around

  • Kirkwood Station - 14 min drive
  • St. Louis Lambert Intl. Airport (STL) - 31 min drive

Restaurants

  • ‪Burger King - ‬10 min walk
  • ‪Popeyes Louisiana Kitchen - ‬3 min walk
  • ‪Starbucks - ‬9 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive
  • ‪Hardee's / Red Burrito - ‬10 min walk

About this property

Hampton Inn & Suites St. Louis/South I-55

Hotel in St. Louis with free breakfast and a fitness center
Guests staying at Hampton Inn & Suites St. Louis/South I-55 enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include conference space, a business center, and coffee/tea in a common area.
37-inch LCD TVs come with cable channels and pay movies, and guests can stay connected with free WiFi and wired Internet. Bathrooms offer hair dryers and free toiletries. Refrigerators, microwaves, and coffee makers are other standard amenities.
Recreational amenities at the hotel include an indoor pool and a fitness center.

Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business center
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 75 per accommodation, per stay
  • Dogs and cats only
  • 2 total pets
  • Pets may not be left unsupervised
  • Service animals exempt from fees

Children and extra beds

  • Free cribs/infant beds are available

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
  • Check-in: 3 PM—-midnight
  • Check-out: 11 AM
The front desk is open 24 hours a day, and checking in is easy with express services. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards and debit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • This property reserves the right to pre-authorize the guest's credit card prior to arrival.

Additional information about polices, regulations, and more:

  • Pool access available from 8 AM to 10 PM.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55

Frequently asked questions

Are free cancellation options available at Hampton Inn & Suites St. Louis/South I-55?

Hampton Inn & Suites St. Louis/South I-55 offers free cancellation on certain room rates. For more details, review the cancellation policy on Orbitz.

How much does it cost to stay at Hampton Inn & Suites St. Louis/South I-55?

As of Nov 6, 2025, prices found for a 1-night stay for 2 adults at Hampton Inn & Suites St. Louis/South I-55 on Nov 16, 2025 start from $111.2, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to see near Hampton Inn & Suites St. Louis/South I-55?

This hotel is located in St. Louis, close to Grant's Farm, River City Casino, and Missouri Civil War Museum. You'll also find Meramec River and Suson Park within a short drive.

Will I be able to park at Hampton Inn & Suites St. Louis/South I-55?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Does Hampton Inn & Suites St. Louis/South I-55 include a casino on the premises?

No, Hampton Inn & Suites St. Louis/South I-55 doesn't have a casino.

Will I find an indoor pool at Hampton Inn & Suites St. Louis/South I-55?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 10 PM.

What do couples enjoy most about Hampton Inn & Suites St. Louis/South I-55?

Couples staying at this hotel will appreciate amenities like free Internet access as well as an indoor pool and free breakfast.

Are there hot tubs at Hampton Inn & Suites St. Louis/South I-55?

No, there isn't a spa tub at this hotel.

Does Hampton Inn & Suites St. Louis/South I-55 have a restaurant with a breakfast menu?

Hampton Inn & Suites St. Louis/South I-55 offers free buffet breakfast each morning though there is no restaurant.

Will Hampton Inn & Suites St. Louis/South I-55 allow pets to stay free of charge?

Although they can't stay for free, cats and dogs are welcome at Hampton Inn & Suites St. Louis/South I-55 for a fee of USD 75 per accommodation, per stay.

Does Hampton Inn & Suites St. Louis/South I-55 have connecting rooms?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

Where is the closest airport to Hampton Inn & Suites St. Louis/South I-55?

The closest major airport to Hampton Inn & Suites St. Louis/South I-55 is St. Louis Lambert Intl. Airport (STL), which is 26.1 mi away (31 minutes by car). Another top airport is St. Louis, MO (SUS-Spirit of St. Louis), which is located 26.2 mi away (31-minute drive).

Are there rooms with balconies that I can book at Hampton Inn & Suites St. Louis/South I-55?

No, you won't find guestrooms with balconies at Hampton Inn & Suites St. Louis/South I-55.

Hampton Inn & Suites St. Louis/South I-55 Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 824 out of 1000 reviews
Rating 8 - Good. 128 out of 1000 reviews
Rating 6 - Okay. 27 out of 1000 reviews
Rating 4 - Poor. 5 out of 1000 reviews
Rating 2 - Terrible. 16 out of 1000 reviews

9.8/10

Cleanliness

9.8/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Peter

Liked: Cleanliness, staff & service, property conditions & facilities
Nice place
Stayed 1 night in Jul 2025

10/10 Excellent

john

Stayed 1 night in Aug 2025

8/10 Good

Lisa

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Aug 2025

10/10 Excellent

Michael

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Diane

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Be clear on what you want

A little confusing when asking for towels/ washcloths but seemed to work out on day 3!
Stayed 4 nights in Jul 2025

10/10 Excellent

Bailey

Stayed 2 nights in Jul 2025

6/10 Okay

Bert

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Bad security guard

Got in late and there was a “make-shift” pvc barrier with stop signs on it with a woman with a clipboard. We stopped and rolled down the window and SHE JUST WALKED RIGHT PAST US to the back of the truck. Got our tag then came up to the window and asked which hotel we’re staying. I said “Who are you!”? She got mad and said “I’m hotel SECURITY!” I replied “Ok, next time ID yourself for my safety and yours!”. As I drove off she said something with real attitude because of how she was shaking her head. Bad intro. But check in was awesome and room was great.
Stayed 1 night in Jul 2025

10/10 Excellent

Brittany

Traveled with family and small children
Liked: Cleanliness, staff & service, property conditions & facilities
Everything was great! Clean, comfortable and breakfast was fantastic!
Stayed 1 night in Jul 2025

10/10 Excellent

Loni

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

John

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

8/10 Good

Ellene

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I think breakfast could be better.
Stayed 5 nights in Jul 2025

10/10 Excellent

John

Traveled with family
The best hotel staff I’ve ever encountered.
Stayed 2 nights in Jul 2025

10/10 Excellent

Jonathan

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Fun trip

Went with family friends and we all stayed here and had a great experience.
Stayed 2 nights in Jul 2025

2/10 Terrible

Avdo, Saint Louis

Stayed 3 nights in Jul 2025

10/10 Excellent

Emma

Stayed 5 nights in Jul 2025

8/10 Good

Tracy

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The wallpaper in the bathroom was coming up in a few different places.
Stayed 3 nights in Jul 2025

10/10 Excellent

David

Liked: Staff & service, property conditions & facilities, room comfort

Very good room and helpfull staff

Stayed 1 night in Jul 2025

10/10 Excellent

Curtis

Stayed 2 nights in Jul 2025

10/10 Excellent

Miguel

Stayed 1 night in Jun 2025

10/10 Excellent

Robert

Stayed 1 night in Jun 2025

10/10 Excellent

Ralph

Traveled with family
Great experience.
Stayed 1 night in Jun 2025

10/10 Excellent

Beverly

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The staff here are incredibly professional and friendly, creating a welcoming environment that makes you feel right at home. The rooms are spotless, adding to the overall sense of comfort. The atmosphere is truly delightful! I highly encourage you to experience it for yourself!
Stayed 1 night in Jun 2025

10/10 Excellent

Carl

Business traveler
Nice clean rooms updated.
Stayed 1 night in Jun 2025

10/10 Excellent

Jane

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025

10/10 Excellent

Sandro, Sao Paulo

Liked: Cleanliness, staff & service, property conditions & facilities
Great experience for a weekend in St Louis, the hotel convenience is great, staff very polite in the breakfast and all match with the content in the site, recommend!
Stayed 2 nights in Jun 2025