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Hampton Inn & Suites St. Louis/South I-55

2.5 star property

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Photo gallery for Hampton Inn & Suites St. Louis/South I-55

Lobby
Room | In-room safe, blackout drapes, iron/ironing board
One King Bed, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board
Fitness facility
Indoor pool

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
4200 Midamerica Lane, St. Louis, MO, 63129
  • Place, Barnes Jewish South Campus
    ‪5 min walk‬
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪30 min drive‬

Room options

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.8 out of 10
Exceptional
(36 reviews)
  • 460 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(14 reviews)
  • 460 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 460 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 460 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(27 reviews)
  • 460 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(20 reviews)
  • 460 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking | In-room safe, blackout drapes, iron/ironing board

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)
  • 460 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

King Room-Non-Smoking

  • Sleeps 2

Guest Room With 1 King Bed And Mobility/Hearing Accessible With Tub-Nonsmoking

  • Sleeps 2

King Studio Suite With Whirlpool-Non-Smoking

  • Sleeps 3

2 Queen Beds Room, Non-Smoking

  • Sleeps 4

Mobility Hearing Accessible King Studio with Roll in Shower

  • Sleeps 3

2 Queens Mobility/Hearing Access Tub Nosmok

  • Sleeps 4

King Studio Suite-Non-Smoking

  • Sleeps 3

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About the neighborhood

St. Louis

Located within a leisurely stroll of Barnes Jewish South Campus, Hampton Inn & Suites St. Louis/South I-55 is within a few miles (5 km) of St Anthony's. This 92-room hotel welcomes guests with conveniences like free breakfast, an indoor pool, and free in-room WiFi.

What's nearby

  • Barnes Jewish South Campus - 5 min walk - 0.3 miles
  • Busch Stadium - 16 min drive - 16.9 miles
  • Gateway Arch - 17 min drive - 17.3 miles
  • Enterprise Center - 17 min drive - 16.7 miles
  • St. Louis Union Station - 18 min drive - 16.9 miles

Getting around

  • Kirkwood Station - 14 min drive
  • St. Louis Lambert Intl. Airport (STL) - 31 min drive

Restaurants

  • ‪McDonald's - ‬3 min drive
  • ‪Burger King - ‬10 min walk
  • ‪Popeyes Louisiana Kitchen - ‬3 min walk
  • ‪Hardee's / Red Burrito - ‬10 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive

About this property

Hampton Inn & Suites St. Louis/South I-55

Guests staying at Hampton Inn & Suites St. Louis/South I-55 enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include conference space, a business center, and coffee/tea in a common area.
37-inch LCD TVs come with cable channels and pay movies, and guests can stay connected with free WiFi and wired Internet. Bathrooms offer hair dryers and free toiletries. Refrigerators, microwaves, and coffee makers are other standard amenities.
Recreational amenities at the hotel include an indoor pool and a fitness center.

Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision.

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Property amenity
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
9.6 out of 10, Exceptional, 1,002 reviews
$125 nightly
The price is $144
Apr 5 - Apr 6
Total with taxes and fees
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business center
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 75 per accommodation, per stay
  • Dogs and cats only
  • 2 total pets
  • Pets may not be left unsupervised
  • Service animals exempt from fees

Children and extra beds

  • Free cribs/infant beds are available

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
  • Check-in: 3 PM—-midnight
  • Check-out: 11 AM
The front desk is open 24 hours a day, and checking in is easy with express services. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards and debit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • This property reserves the right to pre-authorize the guest's credit card prior to arrival.

Additional information about polices, regulations, and more:

  • Pool access available from 8 AM to 10 PM.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55

Frequently asked questions

Are free cancellation options available at Hampton Inn & Suites St. Louis/South I-55?

Hampton Inn & Suites St. Louis/South I-55 offers free cancellation on certain room rates. For more details, review the cancellation policy on Orbitz.

How much does it cost to stay at Hampton Inn & Suites St. Louis/South I-55?

As of Mar 23, 2026, prices found for a 1-night stay for 2 adults at Hampton Inn & Suites St. Louis/South I-55 on Apr 5, 2026 start from $126, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to see near Hampton Inn & Suites St. Louis/South I-55?

This hotel is located in St. Louis, close to Grant's Farm, River City Casino, and Jefferson Barracks Historic Park. You'll also find Meramec River and Suson Park within a short drive.

Is parking available on site at Hampton Inn & Suites St. Louis/South I-55?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Does Hampton Inn & Suites St. Louis/South I-55 include a casino on the premises?

No, Hampton Inn & Suites St. Louis/South I-55 doesn't have a casino.

Will I find an indoor pool at Hampton Inn & Suites St. Louis/South I-55?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 10 PM.

What will couples enjoy most about a stay at Hampton Inn & Suites St. Louis/South I-55?

Couples staying at this hotel will appreciate amenities like free Internet access as well as an indoor pool and free breakfast.

Are there hot tubs at Hampton Inn & Suites St. Louis/South I-55?

No, there isn't a spa tub at this hotel.

Does Hampton Inn & Suites St. Louis/South I-55 have a restaurant with a breakfast menu?

Hampton Inn & Suites St. Louis/South I-55 offers free buffet breakfast each morning though there is no restaurant.

Will Hampton Inn & Suites St. Louis/South I-55 allow pets to stay free of charge?

Although they can't stay for free, cats and dogs are welcome at Hampton Inn & Suites St. Louis/South I-55 for a fee of USD 75 per accommodation, per stay.

Does Hampton Inn & Suites St. Louis/South I-55 have connecting rooms?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

Where is the closest airport to Hampton Inn & Suites St. Louis/South I-55?

The closest major airport to Hampton Inn & Suites St. Louis/South I-55 is St. Louis Lambert Intl. Airport (STL), which is 26.1 mi away (31 minutes by car). Another top airport is St. Louis, MO (SUS-Spirit of St. Louis), which is located 26.2 mi away (31-minute drive).

Can I book a room with a balcony at Hampton Inn & Suites St. Louis/South I-55?

No, at Hampton Inn & Suites St. Louis/South I-55, there aren't any guestrooms that list a balcony.

Hampton Inn & Suites St. Louis/South I-55 Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 821 out of 1000 reviews
Rating 8 - Good. 128 out of 1000 reviews
Rating 6 - Okay. 27 out of 1000 reviews
Rating 4 - Poor. 5 out of 1000 reviews
Rating 2 - Terrible. 19 out of 1000 reviews

9.8/10

Cleanliness

9.8/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

2/10 Terrible

Jason

Liked: Staff & service
Disliked: Cleanliness, amenities
The room was supposed to be a king suite with a jacuzzi tub and spent 350 on it and ended up getting a standard suite handicapped accessible
Stayed 2 nights in Dec 2025

10/10 Excellent

Paul

Stayed 1 night in Dec 2025

10/10 Excellent

Joan

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 4 nights in Dec 2025

8/10 Good

Gretchen

Clean room
Stayed 3 nights in Dec 2025

10/10 Excellent

SHELLY

Traveled with family
Liked: Cleanliness, staff & service, amenities
Clean room, good breakfast. Nice, safe area. But the staff was the best I have encountered in a long time. From check in, check out to the breakfast staff. I cannot say enough. We stayed 12/6/25 - one night and I would come back in a heartbeat.
Stayed 1 night in Dec 2025

8/10 Good

Jeffrey

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good. The staff was friendly and they allowed us to check out late.
Stayed 1 night in Dec 2025

2/10 Terrible

Tabitha

Liked: Cleanliness
Disliked: Staff & service
Upon check in at 4am which I understand is not check in time there was a hiccup. On hotels.com I booked check-in Monday check out Tuesday and paid online almost two hundred dollars and change. During check in the lady pointed out that I booked an accesible room and did I want. No, I said but the app didn’t show me another room with two beds. I wouldn’t want to take an accesible room away from somebody who might need it. So, she said she could switch it no problem or changes. I go to sign the papers and it had me checking out same day, but that’s not what my itinerary on the app and in my email stated almost two hundred dollars paid for check out Tuesday. She would not honor my booking with hotels.com the way it was booked. She wouldn’t let me pay to check in early because it was 4 am Monday and I was exhausted and also had my dog which was almost a hundred per night. I had to pay almost four hundred because they count 4am as Sunday. Whats crazy is the system only charged me one night dog fee, so it recognized my dog was there for 1 night but not me. I paid for insurance on hotels.com and contacted them and they contacted the hotel. I got refunded the original amountfrom the website. There’s that, but I stayed in another hotel recently that let me check in around midnight for just an extra 20 added to my total. Charging a whole extra night for checking in 7 hours early (I was told at 11 it turns into the next day) seems a bit much. A lesson learned if I ever stay here again.
Stayed 1 night in Dec 2025

8/10 Good

Jessica

Liked: Cleanliness, property conditions & facilities, room comfort
The room was very nice and seemed pretty updated. Bathroom was huge for a hotel bathroom. The shower was underwhelming and the beds weren't the most comfortable. Overall it was pretty nice and i would stay here again if im in the area.
Stayed 1 night in Nov 2025

10/10 Excellent

Randall

Stayed 1 night in Nov 2025

8/10 Good

Cynthia

Traveled with family
Liked: Cleanliness, staff & service, amenities
The room was clean and we just needed a bed to sleep in! It was fine
Stayed 1 night in Nov 2025

10/10 Excellent

Samiha

Nice room! regular cleaning. Good breakfast. Staffs are welcoming.
Stayed 3 nights in Nov 2025

10/10 Excellent

Amy

Traveled with family and small children, Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was nice and friendly. Room was nice and clean.
Stayed 1 night in Nov 2025

10/10 Excellent

Sherry

Stayed 1 night in Oct 2025

10/10 Excellent

Michael

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff.
Stayed 1 night in Oct 2025

10/10 Excellent

Lísbeth

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I’m a traveling band mom, so I’ve been in three different hotel franchises in the last three weeks. This was the best! When I walked in, I was shocked at how crisp and clean everything was. Great service, they let me check in early, which was extremely helpful. The room was noiiiiiice! And I really need to know where I can buy their shampoo and conditioner, because my hair has never been so manageable. I didn’t have time to swim, but their pool has play stuff and it’s nice and warm in there. I will be back! It’s a great distance from St Louis, you can get there in no time and still be in the burbs
Stayed 2 nights in Oct 2025

10/10 Excellent

Eric

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
Big and comfortable rooms with excellent services
Stayed 1 night in Oct 2025

8/10 Good

Melinda

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
yes
Stayed 1 night in Oct 2025

10/10 Excellent

Vicenta Fe

Traveled with group, Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I liked everything about this Hampton Inn, from the staff, room, amenities, breakfast, cleanliness, location and parking are all superb. Will definitely come back
Stayed 1 night in Oct 2025

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Didn't use
Stayed 3 nights in Oct 2025

8/10 Good

Fernando

Business traveler, Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good
Stayed 1 night in Oct 2025

10/10 Excellent

James, dolton

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was so helpful. We came for a funeral. Our room was not, ready, we needed to check in early. I was in consent contact with your staff about early check in, we needed to change clothes before going to the funeral. I was told they would do everything to accommodate us. The rooms were being cleaned when we arrived, but we would be late if we waited to change, so your staff allowed use to change in a vacant conference room, it was 5 of us. They check to see how long it would take us to get to the funeral. The staff was just so caring and sincere. We made it on time to share this difficult time with our family. Blessings to your staff. The Sanders family.
Stayed 1 night in Sep 2025

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025

10/10 Excellent

Steven

Liked: Cleanliness, property conditions & facilities
Stayed 2 nights in Sep 2025

10/10 Excellent

Ariona, House Springs

Traveled with family
Liked: Amenities
Our room was cleaned by Tiff and it was in perfect condition. Pool area was clean as well as the lobby and dining area. You can tell the staff cares. Everyone was very hospitable at breakfast. I also love that you can tip the support staff through the qr code. Would highly reccomend
Stayed 1 night in Aug 2025

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