Hampton Inn & Suites St. Louis/South I-55
Hotel in St. Louis with free breakfast and a fitness center
Choose dates to view prices
Photo gallery for Hampton Inn & Suites St. Louis/South I-55





Reviews
9.6 out of 10
Exceptional
Popular amenities
Explore the area

4200 Midamerica Lane, St. Louis, MO, 63129
- Place, Mercy Hospital South4 min drive
- Place, River City Casino10 min drive
- Place, Grant's Farm13 min drive
- Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)30 min drive
Room options
View all photos for Room

Room
9.8 out of 10
Exceptional
(34 reviews)
View all photos for Room

Room
9.6 out of 10
Exceptional
(14 reviews)
View all photos for Room

Room
9.6 out of 10
Exceptional
(4 reviews)
View all photos for Room

Room
10.0 out of 10
Exceptional
(2 reviews)
View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible
9.8 out of 10
Exceptional
(26 reviews)
View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible
9.8 out of 10
Exceptional
(18 reviews)
View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking
9.2 out of 10
Wonderful
(5 reviews)
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Chesterfield
- Pool
- Breakfast included
- Pet friendly
- Parking included
8.8 out of 10, Excellent, 830 reviews
$99 nightly
The price is $115
Nov 21 - Nov 22
Total with taxes and fees
About the neighborhood
About this property
Hampton Inn & Suites St. Louis/South I-55
Similar properties

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
- Pool
- Breakfast included
- Parking included
- Free WiFi
9.6 out of 10, Exceptional, 1,000 reviews
$118 nightly
The price is $136
Nov 9 - Nov 10
Total with taxes and fees
Property amenities
Room amenities
Policies
Important information
Frequently asked questions
Hampton Inn & Suites St. Louis/South I-55 Reviews
Reviews
9.6
Exceptional
9.8/10
Cleanliness
9.8/10
Staff & service
9.4/10
Amenities
9.6/10
Property conditions & facilities
9.2/10
Eco-friendliness
Reviews
Aug 6, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Jul 2025
10/10 Excellent
john
Aug 4, 2025
john
Stayed 1 night in Aug 2025
8/10 Good
Lisa
Traveled with family
Aug 4, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Lisa
Stayed 1 night in Aug 2025
10/10 Excellent
Michael
Traveled with family
Aug 4, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Michael
Stayed 1 night in Aug 2025
10/10 Excellent
Diane
Traveled with family
Jul 30, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Be clear on what you want
Diane
Stayed 4 nights in Jul 2025
10/10 Excellent
Bailey
Jul 28, 2025
Bailey
Stayed 2 nights in Jul 2025
6/10 Okay
Bert
Traveled with group
Jul 27, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Bad security guard
Bert
Stayed 1 night in Jul 2025
10/10 Excellent
Brittany
Traveled with family and small children
Jul 27, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Brittany
Stayed 1 night in Jul 2025
10/10 Excellent
Loni
Jul 22, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Loni
Stayed 1 night in Jul 2025
10/10 Excellent
John
Traveled with family
Jul 21, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
John
Stayed 1 night in Jul 2025
8/10 Good
Ellene
Traveled with family
Jul 19, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Ellene
Stayed 5 nights in Jul 2025
10/10 Excellent
John
Traveled with family
Jul 15, 2025
John
Stayed 2 nights in Jul 2025
10/10 Excellent
Jonathan
Traveled with family
Jul 13, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Fun trip
Jonathan
Stayed 2 nights in Jul 2025
2/10 Terrible
Avdo, Saint Louis
Jul 13, 2025
Avdo
Stayed 3 nights in Jul 2025
10/10 Excellent
Emma
Jul 9, 2025
Emma
Stayed 5 nights in Jul 2025
8/10 Good
Tracy
Traveled with family
Jul 8, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Tracy
Stayed 3 nights in Jul 2025
10/10 Excellent
David
Jul 6, 2025
Liked: Staff & service, property conditions & facilities, room comfort
Very good room and helpfull staff
David
Stayed 1 night in Jul 2025
10/10 Excellent
Curtis
Jul 6, 2025
Curtis
Stayed 2 nights in Jul 2025
10/10 Excellent
Miguel
Jul 2, 2025
Miguel
Stayed 1 night in Jun 2025
10/10 Excellent
Robert
Jul 2, 2025
Robert
Stayed 1 night in Jun 2025
10/10 Excellent
Ralph
Traveled with family
Jul 1, 2025
Ralph
Stayed 1 night in Jun 2025
10/10 Excellent
Beverly
Traveled with family
Jun 22, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Beverly
Stayed 1 night in Jun 2025
10/10 Excellent
Carl
Business traveler
Jun 17, 2025
Carl
Stayed 1 night in Jun 2025
10/10 Excellent
Jane
Traveled with family
Jun 17, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Jane
Stayed 2 nights in Jun 2025
10/10 Excellent
Sandro, Sao Paulo
Jun 16, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Sandro
Stayed 2 nights in Jun 2025
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