Hotels with Casino in Southeast Missouri, MO
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Southeast Missouri Casino Resorts & Hotels

Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84, Hayti, MO
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $107 total per night
$107 total
Nov 23 - Nov 24
Total with taxes and fees
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Town House Inn Cape Giradreau
505 North Kingshighway Street, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$73 nightly
The price is $82 total per night
$82 total
Nov 16 - Nov 17
Total with taxes and fees
Town House Inn Cape Giradreau features free WiFi in public areas and a vending machine. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Free Cancellation
$91 nightly
The price is $103 total per night
$103 total
Nov 30 - Dec 1
Total with taxes and fees
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included

Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $79 total per night
$79 total
Nov 17 - Nov 18
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau Near the Medical Center enjoy free WiFi in public areas, coffee in a common area, and express check-out. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free hotel also has a TV in a common area.
Pet friendly
Free WiFi

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
Free Cancellation
$77 nightly
The price is $92 total per night
$92 total
Nov 16 - Nov 17
Total with taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $79 total per night
$79 total
Nov 17 - Nov 18
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly

Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $102 total per night
$102 total
Nov 23 - Nov 24
Total with taxes and fees
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$58 nightly
The price is $65 total per night
$65 total
Nov 19 - Nov 20
Total with taxes and fees
Guests of Quality Inn enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a vending machine, and a TV in a common area.
Pool
Breakfast included

Quality Inn Hayti North
1500 Highway 84, Hayti, MO
Free Cancellation
Reserve now, pay when you stay
$62 nightly
The price is $71 total per night
$71 total
Nov 23 - Nov 24
Total with taxes and fees
Quality Inn Hayti North features free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Pool
Breakfast included

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
$87 nightly
The price is $94 total per night
$94 total
Dec 7 - Dec 8
Total with taxes and fees
At Comfort Suites Jackson-Cape Girardeau, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 600 hotels |
|---|---|
Lowest Price | $65 |
Highest Price | $107 |
Popular hotels | Drury Inn & Suites Hayti Caruthersville, Town House Inn Cape Giradreau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Pear Tree Inn Cape Girardeau Near the Medical Center, Candlewood Suites Cape Girardeau by IHG, Pear Tree Inn Cape Girardeau West, Drury Inn & Suites Cape Girardeau, Quality Inn, Quality Inn Hayti North, Comfort Suites Jackson-Cape Girardeau |
Recent Casino Resorts & Hotels Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
5/5 Excellent
"Thanks "
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Posted 4 days ago
More to Explore
- 3 Star Hotels in Ironton
- B&B in Ironton
- Cottages in Ironton
- Cheap Hotels in Ironton
- Historic Hotels in Ironton
- Hotels with Bar in Ironton
- Ironton Hotels
- Motels in Ironton
- Vacation Homes in Ironton
- B&B in Pilot Knob
- Kid Friendly Hotels in Pilot Knob
- Hotels with Pool in Pilot Knob
- Hotels with Air Conditioning in Pilot Knob
- Pilot Knob Hotels
- Des Arc Hotels
- 2 Star Hotels in Central Fredericktown
- Historic Hotels in Caledonia
- Hotels with Pool in Ellington
- Cabin Rentals in Piedmont
- Condo Rentals in Piedmont
- Pet Friendly Hotels in Piedmont
- Piedmont Hotels
- Lodges in Piedmont
- Motels in Piedmont
- Apartments in Arcadia Valley Station
- Cabin Rentals in Arcadia Valley Station
- Cabin Rentals in Marble Hill
- Hotels near K Bridge Recreation Area
- Mill Spring Hotels
- Motels in Mill Spring
- 3 Star Hotels in Fredericktown
- 5 Star Hotels in Fredericktown
- B&B in Fredericktown
- Cabin Rentals in Fredericktown
- Condo Rentals in Fredericktown
- Cottages in Fredericktown
- Pet Friendly Hotels in Fredericktown
- Fredericktown Hotels
- Motels in Fredericktown
- Cottages in Middle Brook
- Cobalt Hotels
- Casino Resorts & in Farmington
- Cheap Hotels in Farmington
- Kid Friendly Hotels in Farmington
- Golf Resorts & in Farmington
- Historic Hotels in Farmington
- Hotels with Pool in Farmington
- Hotels with Hot Tubs in Farmington
- Hotels with an Indoor Pool in Farmington
- Luxury Hotels in Farmington
- Pet Friendly Hotels in Farmington
- Romantic Getaways & Hotels in Farmington
- Spa Resorts & in Farmington
- Hotels with a Wedding Venue in Farmington
- Winery Hotels in Farmington
- Hotels near Taum Sauk Mountain State Park
- All Inclusive Resorts & in Downtown St. Louis
- Hotels with a Gym in Downtown St. Louis
- Hotels with Room Service in Downtown St. Louis
- Luxury Hotels in Downtown St. Louis
- Hotels on the River in Downtown St. Louis
- Hotels with Shopping in Downtown St. Louis
- B&B in Annapolis
- Cabin Rentals in Annapolis
- Vacation Homes in Annapolis
- Hotels near Elephant Rocks State Park
- Hotels near Millstream Gardens Conservation Area
- Lodges in Greenville
- Rv Parks in Greenville
- Resorts in Greenville
- Hotels near Fort Davidson State Historic Site
- Hotels with Airport Transfers in St. Louis
- Beach Resorts & in Park Hills
- Hotels with Pool in Park Hills
- 3 Star Hotels in Arcadia
- 4 Star Hotels in Arcadia
- Cabin Rentals in Arcadia
- Cottages in Arcadia
- Hotels with Pool in Arcadia
- Motels in Arcadia
- 4 Star Hotels in Lesterville
- Apartments in Lesterville
- Cabin Rentals in Lesterville
- Cottages in Lesterville
- Kid Friendly Hotels in Lesterville
- Hotels with Pool in Lesterville
- Pet Friendly Hotels in Lesterville
- Lodges in Lesterville
- Vacation Homes in Lesterville


