Hotels with Casino in Southeast Missouri, MO

Name: Comfort Suites Jackson-Cape Girardeau
Price range: $96 total

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Sep 28 - Sep 29

Tonight

Sep 29 - Sep 30

Tomorrow night

Featured Southeast Missouri Casino Resorts & Hotels

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

$192 nightly

$205 total

Sep 29 - Sep 30

Total with taxes and fees

At Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG, guests have access to a gym, a sauna, and outdoor tennis courts. If you decide to drive, there's free parking. Front-desk staff can assist with luggage storage and securing valuables. Other amenities at this family-friendly aparthotel include a business center, a seasonal outdoor pool, and an arcade/game room.

Free Cancellation

Reserve now, pay when you stay

$94 nightly

$107 total

Oct 5 - Oct 6

Total with taxes and fees

At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.

Free Cancellation

Reserve now, pay when you stay

$68 nightly

$76 total

Sep 29 - Sep 30

Total with taxes and fees

Town House Inn Cape Giradreau features free WiFi in public areas and a vending machine. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Free Cancellation

$95 nightly

$107 total

Oct 19 - Oct 20

Total with taxes and fees

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.

Pear Tree Inn Cape Girardeau Near the Medical Center

Free Cancellation

Reserve now, pay when you stay

$70 nightly

$79 total

Oct 2 - Oct 3

Total with taxes and fees

Guests of Pear Tree Inn Cape Girardeau Near the Medical Center enjoy free WiFi in public areas, coffee in a common area, and express check-out. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free hotel also has a TV in a common area.

Free Cancellation

$74 nightly

$89 total

Oct 2 - Oct 3

Total with taxes and fees

At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.

Free Cancellation

Reserve now, pay when you stay

$70 nightly

$79 total

Oct 2 - Oct 3

Total with taxes and fees

Renovated in 2025, Pear Tree Inn Cape Girardeau West offers a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.

Free Cancellation

Reserve now, pay when you stay

$90 nightly

$102 total

Oct 2 - Oct 3

Total with taxes and fees

Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.

Free Cancellation

Reserve now, pay when you stay

$61 nightly

$68 total

Oct 16 - Oct 17

Total with taxes and fees

Guests of Quality Inn enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a vending machine, and a TV in a common area.

Free Cancellation

Reserve now, pay when you stay

$67 nightly

$77 total

Oct 27 - Oct 28

Total with taxes and fees

Quality Inn Hayti North features free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.

Free Cancellation

Reserve now, pay when you stay

$89 nightly

$96 total

Oct 5 - Oct 6

Total with taxes and fees

At Comfort Suites Jackson-Cape Girardeau, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and a computer station.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri hotels essential information

Accommodation	605 hotels
Lowest Price	$68
Highest Price	$205
Popular hotels	Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG, Drury Inn & Suites Hayti Caruthersville, Town House Inn Cape Giradreau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Pear Tree Inn Cape Girardeau Near the Medical Center, Candlewood Suites Cape Girardeau by IHG, Pear Tree Inn Cape Girardeau West, Drury Inn & Suites Cape Girardeau, Quality Inn, Quality Inn Hayti North, Comfort Suites Jackson-Cape Girardeau

Recent Casino Resorts & Hotels Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

5/5 Excellent

"My partner and I were in town for a family wedding and stayed for 3 nights. The staff at this hotel were amazing! They were, over the top, friendly and helpful with anything we needed. They allowed us to gather with family outside on the patio and checked on us several times. The room was clean, the bed was super comfortable, breakfast was great and we loved the patio area. Overall, it was a wonderful experience!"

A verified traveler stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Posted 3 days ago