Hotels in Southeast Missouri
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Top Rated Southeast Missouri Hotels
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Oct 25 - Oct 26
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
$94 nightly
The price is $108 total per night
$108 total
Oct 25 - Oct 26
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
$54 nightly
The price is $61 total per night
$61 total
Nov 15 - Nov 16
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Breakfast included
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.8 mi from city center
$72 nightly
The price is $81 total per night
$81 total
Oct 25 - Oct 26
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly
Hampton Inn Poplar Bluff
2420 Crestwood Dr Poplar Bluff MO
Free Cancellation
Reserve now, pay when you stay
30.36 mi from city center
$91 nightly
The price is $102 total per night
$102 total
Nov 1 - Nov 2
Total with taxes and fees
Guests of Hampton Inn Poplar Bluff have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
54.5 mi from city center
$66 nightly
The price is $76 total per night
$76 total
Nov 1 - Nov 2
Total with taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a banquet hall.
Breakfast included
Pet friendly
The Riverview
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
50.35 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Nov 10 - Nov 11
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and wedding services.
Parking included
Free WiFi
Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
Free Cancellation
68.39 mi from city center
$73 nightly
The price is $83 total per night
$83 total
Nov 12 - Nov 13
Total with taxes and fees
At Comfort Inn Festus - St Louis South, guests have access to a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and tours or tickets. Additional amenities include free newspapers, laundry facilities, and a vending machine.
Breakfast included
Parking included
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
$80 nightly
The price is $86 total per night
$86 total
Nov 1 - Nov 2
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a banquet hall.
Pool
Breakfast included
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
51.43 mi from city center
$141 nightly
The price is $160 total per night
$160 total
Nov 17 - Nov 18
Total with taxes and fees
At Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy, guests have access to features like express check-out. You can put free parking to good use if you drive.
Kitchen
Pet friendly
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
41.04 mi from city center
$331 nightly
The price is $370 total per night
$370 total
Oct 20 - Oct 21
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities.
Kitchen
Laundry
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
52.79 mi from city center
$105 nightly
The price is $120 total per night
$120 total
Nov 1 - Nov 2
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check Southeast Missouri hotel room prices by star rating
4 Star Hotels
2 properties
Stay near popular Southeast Missouri attractions
Cheap Southeast Missouri hotels options
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
$77 nightly
The price is $86 total per night from Oct 21 to Oct 22
$86 total
Oct 21 - Oct 22
Total with taxes and fees
Super 8 by Wyndham Farmington
930 Valley Creek Dr Farmington MO
$60 nightly
The price is $68 total per night from Oct 25 to Oct 26
$68 total
Oct 25 - Oct 26
Total with taxes and fees
Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
$75 nightly
The price is $86 total per night from Oct 20 to Oct 21
$86 total
Oct 20 - Oct 21
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Oct 25 to Oct 26
$81 total
Oct 25 - Oct 26
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
$54 nightly
The price is $61 total per night from Nov 15 to Nov 16
$61 total
Nov 15 - Nov 16
Total with taxes and fees
8/10 Very Good! (1,008 reviews)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$66 nightly
The price is $76 total per night from Nov 1 to Nov 2
$76 total
Nov 1 - Nov 2
Total with taxes and fees
Southeast Missouri hotels essential information
Accommodation | 697 hotels |
|---|---|
Lowest Price | $61 |
Highest Price | $370 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, Drury Inn & Suites Sikeston, MO, Baymont Inn and Suites by Wyndham Farmington, MO, Pear Tree Inn Cape Girardeau West, Hampton Inn Poplar Bluff, Days Inn and Suites by Wyndham Sikeston, The Riverview, Comfort Inn Festus - St Louis South, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy, Silo Farm Haus- located in the heart of wine country!, Hampton Inn Sikeston |
Recent Reviews
Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"This hotel and staff was first class."
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted less than an hour ago
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