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Top Rated Southeast Missouri Hotels

Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5.0 3265 William St, Cape Girardeau, MO
Free Cancellation
$69
4.5/5 (49 reviews)

Good stay for the price, clean, nice staff, breakfast was a little cold but all the usual amenities were present.

Reviewed on Nov 10, 2019
Guests staying at Auburn Place Hotel And Suites enjoy an indoor pool, a fitness center, and a spa tub. A stay here includes free parking. Front-desk staff can ...
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 out of 5.0 3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
$99
5.0/5 (6 reviews)

Everything was perfect from the moment I walked through the door, no complaints.

Reviewed on Sep 11, 2018
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a 24-hour fitness center, and a spa tub. You can take advantage ...
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5.0 103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
$63
3.9/5 (13 reviews)

Room was very clean, bigger sized bathroom. Only downfall was the temp of the room, very warm!

Reviewed on Dec 17, 2019
Guests of Pear Tree Inn Cape Girardeau West enjoy a fitness center, free WiFi in public areas, and a 24-hour business center. You can put free parking to good ...
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5.0 3248 William St, Cape Girardeau, MO
Free Cancellation
$63
3.9/5 (53 reviews)

The bathroom was very tiny, although 6 foot and 250 pounds Somethings seem small, but your front desk lady was absolutely amazing

Reviewed on Dec 1, 2019
At Pear Tree Inn Cape Girardeau Near the Medical Center, guests have access to an outdoor pool, free WiFi in public areas, and coffee in a common area. If you ...
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 out of 5.0 3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
$85
4.7/5 (20 reviews)

Very nice large suites!Excellent “snacks” in the evening.We were able to skip dinner and just had their tacos and salad.

Reviewed on Oct 26, 2019
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a fitness center, and a spa tub. A stay here includes free parking. The 24-hour front ...
Pear Tree Inn - Sikeston
Pear Tree Inn - Sikeston
2.5 out of 5.0 2602 E Malone Avenue, Sikeston, MO
Free Cancellation
$76
4.4/5 (20 reviews)

Nice and friendly staff. Beautiful in the inside of the hotel

Reviewed on Apr 1, 2019
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a fitness center. Free parking is included with your stay. The front desk is staffed 24 ...
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 out of 5.0 400 Broadway St., Cape Girardeau, MO
Free Cancellation
$98
5.0/5 (6 reviews)

I loved the feeling of the historical sites. The rooms were so cool and the building was amazing with the history and architectural beauty. It was quiet and so comfortable. I would definitely stay there again.

Reviewed on Oct 12, 2019
Courtyard by Marriott Cape Girardeau Downtown features a 24-hour fitness center, free WiFi in public areas, and a 24-hour business center. A stay here includes ...
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 out of 5.0 2608 East Malone Ave, Sikeston, MO
Free Cancellation
$90
4.5/5 (25 reviews)

Clean and comfortable. The evening meal and drink service kept us from having to go out again to find a restaurant after a long drive. The breakfast was good with a number of choices. The staff were very friendly and helpful.

Reviewed on Oct 1, 2019
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a fitness center. If you drive, put free parking to good use. The front desk is ...
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5.0 207 S Mt Auburn Rd, Cape Girardeau, MO
Free Cancellation
$100
5.0/5 (10 reviews)

I like the fact that the hotel is walking distance of several restaurants. It’s a safe well lit area.

Reviewed on Jan 20, 2020
Built in 2015, the brand new Hampton Inn Cape Girardeau I 55 East offers an indoor pool, a fitness center, and free WiFi in public areas. If you decide to drive, ...

Luxury Hotels in Southeast Missouri

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Pet Friendly Southeast Missouri Hotels

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Southeast Missouri Hotels

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Thanks to photos and virtual tours, you can look before you book your Southeast Missouri hotel reservation. Check out Southeast Missouri hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Southeast Missouri with unbiased reviews from verified Southeast Missouri hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.