Hotels in Southeast Missouri
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Top Rated Southeast Missouri Hotels
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Sep 7 - Sep 8
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub
Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
Free Cancellation
68.39 mi from city center
$73 nightly
The price is $83 total per night
$83 total
Sep 27 - Sep 28
Total with taxes and fees
At Comfort Inn Festus - St Louis South, guests have access to a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. Front-desk staff can answer questions 24/7, and assist with tours or tickets, dry cleaning/laundry, and securing valuables. Additional amenities include free newspapers, laundry facilities, and a gift shop.
Breakfast included
Parking included
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
$57 nightly
The price is $62 total per night
$62 total
Sep 13 - Sep 14
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Breakfast included
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.8 mi from city center
$72 nightly
The price is $81 total per night
$81 total
Sep 7 - Sep 8
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly
The Riverview
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
50.35 mi from city center
$108 nightly
The price is $122 total per night
$122 total
Sep 22 - Sep 23
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and wedding services.
Parking included
Free WiFi
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
41.04 mi from city center
$329 nightly
The price is $368 total per night
$368 total
Sep 7 - Sep 8
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities.
Laundry
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
$94 nightly
The price is $108 total per night
$108 total
Sep 14 - Sep 15
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included
Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84 Hayti MO
Free Cancellation
Reserve now, pay when you stay
78.5 mi from city center
$102 nightly
The price is $116 total per night
$116 total
Sep 20 - Sep 21
Total with taxes and fees
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
Free Cancellation
47.02 mi from city center
$101 nightly
The price is $115 total per night
$115 total
Sep 6 - Sep 7
Total with taxes and fees
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
51.43 mi from city center
$141 nightly
The price is $160 total per night
$160 total
Oct 4 - Oct 5
Total with taxes and fees
At Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy, guests have access to features like express check-out. You can put free parking to good use if you drive.
Kitchen
Pet friendly
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
$93 nightly
The price is $100 total per night
$100 total
Sep 6 - Sep 7
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a vending machine.
Pool
Breakfast included
Holiday Inn Poplar Bluff by IHG
2781 N Westwood Blvd Poplar Bluff MO
Free Cancellation
30.18 mi from city center
$84 nightly
The price is $95 total per night
$95 total
Sep 13 - Sep 14
Total with taxes and fees
At Holiday Inn Poplar Bluff by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include meeting rooms, conference space, and a business center.
Pool
Pet friendly
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
How much is a Southeast Missouri hotel?
Check Southeast Missouri hotel room prices by star rating
4 Star Hotels
2 properties
Stay near popular Southeast Missouri attractions
Cheap Southeast Missouri hotels options
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
$79 nightly
The price is $88 total per night from Sep 5 to Sep 6
$88 total
Sep 5 - Sep 6
Total with taxes and fees
Super 8 by Wyndham Farmington
930 Valley Creek Dr Farmington MO
$60 nightly
The price is $65 total per night from Sep 13 to Sep 14
$65 total
Sep 13 - Sep 14
Total with taxes and fees
8/10 Very Good! (669 reviews)
Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
$68 nightly
The price is $78 total per night from Sep 20 to Sep 21
$78 total
Sep 20 - Sep 21
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Sep 7 to Sep 8
$81 total
Sep 7 - Sep 8
Total with taxes and fees
9.2/10 Wonderful! (1,001 reviews)
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
$57 nightly
The price is $62 total per night from Sep 13 to Sep 14
$62 total
Sep 13 - Sep 14
Total with taxes and fees
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$66 nightly
The price is $76 total per night from Sep 7 to Sep 8
$76 total
Sep 7 - Sep 8
Total with taxes and fees
7.2/10 Good! (1,000 reviews)
Southeast Missouri hotels essential information
Accommodation | 690 hotels |
|---|---|
Lowest Price | $62 |
Highest Price | $368 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, Comfort Inn Festus - St Louis South, Baymont Inn and Suites by Wyndham Farmington, MO, Pear Tree Inn Cape Girardeau West, The Riverview, Silo Farm Haus- located in the heart of wine country!, Drury Inn & Suites Sikeston, MO, Drury Inn & Suites Hayti Caruthersville, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Holiday Inn Poplar Bluff by IHG |
Recent Reviews
Comfort Inn Festus - St Louis South
4/5 Good
"room was clean and the front staff was nice. place served it's purpose (stayed for only 2 nights). Not much amenitites."
A verified traveler stayed at Comfort Inn Festus - St Louis South
Posted 5 hours ago
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