Hotels in Southeast Missouri

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  • Feb 2 - Feb 3
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    Check prices in Southeast Missouri for tonight, Feb 2 - Feb 3
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Top Rated Southeast Missouri Hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
The price is $108 per night
$108
per night
Feb 6 - Feb 7
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a spa tub, a conference center, and a 24-hour business center.
Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

2.5 out of 5
3265 William St, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.97 mi from city center
The price is $75 per night
$75
per night
Feb 5 - Feb 6
Guests staying at Auburn Place Hotel And Suites enjoy an indoor pool, a gym, and free WiFi in public areas. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a 24-hour business center, a meeting room, and laundry facilities.
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
50.01 mi from city center
The price is $139 per night
$139
per night
Feb 9 - Feb 10
Courtyard by Marriott Cape Girardeau Downtown features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. A stay here includes free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include coffee/tea in a common area, a terrace, and laundry facilities.
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

3 out of 5
1317 Highway 84, Hayti, MO, 63851
Free Cancellation
Reserve now, pay when you stay
78.5 mi from city center
The price is $108 per night
$108
per night
Feb 6 - Feb 7
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a spa tub, a business center, and coffee/tea in a common area.
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 out of 5
3253 William Street, Cape Girardeau, MO, 63701
Free Cancellation
47.02 mi from city center
The price is $107 per night
$107
per night
Feb 8 - Feb 9
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include conference space, a business center, and free newspapers.
Candlewood Suites Cape Girardeau, an IHG Hotel

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO, 65703
Free Cancellation
47.21 mi from city center
The price is $96 per night
$96
per night
Feb 5 - Feb 6
At Candlewood Suites Cape Girardeau, an IHG Hotel, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a business center, free newspapers, and laundry facilities.
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.73 mi from city center
The price is $99 per night
$99
per night
Feb 8 - Feb 9
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a spa tub, a business center, and coffee/tea in a common area.
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
The price is $81 per night
$81
per night
Feb 19 - Feb 20
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include free WiFi in public areas, a business center, and coffee/tea in a common area.
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.79 mi from city center
The price is $67 per night
$67
per night
Feb 6 - Feb 7
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
47.07 mi from city center
The price is $67 per night
$67
per night
Feb 7 - Feb 8
Pear Tree Inn Cape Girardeau Near the Medical Center features free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out and a TV in a common area.
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane, Jackson, MO, 63755
Free Cancellation
Reserve now, pay when you stay
45.36 mi from city center
The price is $90 per night
$90
per night
Feb 6 - Feb 7
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a spa tub, a business center, and coffee/tea in a common area.
Travel Inn & Suites

Travel Inn & Suites

2.5 out of 5
100 Matthews Lane, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
54.18 mi from city center
The price is $65 per night
$65
per night
Feb 5 - Feb 6
Guests of Travel Inn & Suites enjoy free WiFi in public areas, coffee in a common area, and a vending machine. If you drive, take advantage of free parking. The 24-hour front desk has staff always at the ready.
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See all available properties in Southeast Missouri
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southeast Missouri

    Super 8 by Wyndham Pevely

    Super 8 by Wyndham Pevely

    1711 Highway Z, Pevely, MO, 63070
    The price is $55 per night from Feb 8 to Feb 9
    $55
    per night
    Feb 8 - Feb 9
    2.8/5 (757 reviews)
    Motel 6 Poplar Bluff, MO

    Motel 6 Poplar Bluff, MO

    4101 Highway 67 N, Poplar Bluff, MO, 63901
    The price is $70 per night from Feb 5 to Feb 6
    $70
    per night
    Feb 5 - Feb 6
    4.1/5 Very Good! (1,010 reviews)
    Days Inn and Suites by Wyndham Sikeston

    Days Inn and Suites by Wyndham Sikeston

    220 S Interstate Dr, Sikeston, MO, 63801
    The price is $72 per night from Feb 8 to Feb 9
    $72
    per night
    Feb 8 - Feb 9
    3.5/5 Good! (855 reviews)

Top Rated Southeast Missouri Hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
The price is $108 per night
$108
per night
Feb 6 - Feb 7
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a spa tub, a conference center, and a 24-hour business center.
Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

2.5 out of 5
3265 William St, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.97 mi from city center
The price is $75 per night
$75
per night
Feb 5 - Feb 6
Guests staying at Auburn Place Hotel And Suites enjoy an indoor pool, a gym, and free WiFi in public areas. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a 24-hour business center, a meeting room, and laundry facilities.
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
50.01 mi from city center
The price is $139 per night
$139
per night
Feb 9 - Feb 10
Courtyard by Marriott Cape Girardeau Downtown features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. A stay here includes free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include coffee/tea in a common area, a terrace, and laundry facilities.
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

3 out of 5
1317 Highway 84, Hayti, MO, 63851
Free Cancellation
Reserve now, pay when you stay
78.5 mi from city center
The price is $108 per night
$108
per night
Feb 6 - Feb 7
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a spa tub, a business center, and coffee/tea in a common area.
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 out of 5
3253 William Street, Cape Girardeau, MO, 63701
Free Cancellation
47.02 mi from city center
The price is $107 per night
$107
per night
Feb 8 - Feb 9
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include conference space, a business center, and free newspapers.
Candlewood Suites Cape Girardeau, an IHG Hotel

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO, 65703
Free Cancellation
47.21 mi from city center
The price is $96 per night
$96
per night
Feb 5 - Feb 6
At Candlewood Suites Cape Girardeau, an IHG Hotel, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a business center, free newspapers, and laundry facilities.
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.73 mi from city center
The price is $99 per night
$99
per night
Feb 8 - Feb 9
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a spa tub, a business center, and coffee/tea in a common area.
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
The price is $81 per night
$81
per night
Feb 19 - Feb 20
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include free WiFi in public areas, a business center, and coffee/tea in a common area.
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
46.79 mi from city center
The price is $67 per night
$67
per night
Feb 6 - Feb 7
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO, 63701
Free Cancellation
Reserve now, pay when you stay
47.07 mi from city center
The price is $67 per night
$67
per night
Feb 7 - Feb 8
Pear Tree Inn Cape Girardeau Near the Medical Center features free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out and a TV in a common area.
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane, Jackson, MO, 63755
Free Cancellation
Reserve now, pay when you stay
45.36 mi from city center
The price is $90 per night
$90
per night
Feb 6 - Feb 7
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a spa tub, a business center, and coffee/tea in a common area.
Travel Inn & Suites

Travel Inn & Suites

2.5 out of 5
100 Matthews Lane, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
54.18 mi from city center
The price is $65 per night
$65
per night
Feb 5 - Feb 6
Guests of Travel Inn & Suites enjoy free WiFi in public areas, coffee in a common area, and a vending machine. If you drive, take advantage of free parking. The 24-hour front desk has staff always at the ready.
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri Hotels

Orbitz makes it easy to find the best Southeast Missouri hotel deals for your trip. With an outstanding selection, easy-to-use search tools and descriptive hotel profiles, you'll find Southeast Missouri hotel deals in a wink..

Great selection of hotels in Southeast Missouri

Whether you're searching for hotels in Southeast Missouri on business, or hunting for a family getaway, Southeast Missouri hotel options are only a click away. Find hotels in Southeast Missouri with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Southeast Missouri hotels close you are to the airport and nearby attractions.

Southeast Missouri hotel reviews, photos and virtual tours

Thanks to photos and virtual tours, you can look before you book your Southeast Missouri hotel reservation. Check out Southeast Missouri hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Southeast Missouri with unbiased reviews from verified Southeast Missouri hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

Grab Southeast Missouri hotel deals and special offers

Orbitz works around the clock to find exclusive offers and Southeast Missouri hotel deals, just for you. Sign up for deals by e-mail where you'll get first crack at money-saving extras like promo codes, resort credits, free nights and more. You can also "Like" Orbitz on Facebook and follow us on Twitter to receive up-to-the-minute news on hotel discounts, giveaways and more.

24/7 support with Southeast Missouri hotel reservations

When it comes to finding hotels in Southeast Missouri, an Orbitz specialist can help you find the property right for you. Chat live or call 1-800-454-3743 any time for help booking your hotels in Southeast Missouri. Our team of experts can help you pinpoint Southeast Missouri hotels options suited to your tastes and budget.

Forget Orbitz change or cancel fees on Southeast Missouri hotels

On Orbitz, Southeast Missouri hotel deals mean flexibility. If you need to change your Southeast Missouri hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to Southeast Missouri all in one place.

 

Recent Reviews

  • Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

    Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

    5/5 Excellent
    "Excellent!!"
    A verified traveler stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
    Posted 2 days ago
    Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

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