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Hotels in Southeast Missouri

Search over 215 hotels from $51

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Top Rated Southeast Missouri Hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southeast Missouri

  • Super 8 by Wyndham Pevely
    Super 8 by Wyndham Pevely
    1711 Highway Z, Pevely, MO
    The price is $51 per night from Feb 2 to Feb 3
    3/5 (30 reviews)
    Super 8 by Wyndham Pevely
  • Motel 6 Poplar Bluff, MO
    Motel 6 Poplar Bluff, MO
    4101 Highway 67 N, Poplar Bluff, MO
    The price is $65 per night from Jan 28 to Jan 29
    4.1/5Very Good! (21 reviews)
    Motel 6 Poplar Bluff, MO
  • Days Inn and Suites by Wyndham Sikeston
    Days Inn and Suites by Wyndham Sikeston
    220 S Interstate Dr, Sikeston, MO
    The price is $65 per night from Feb 15 to Feb 16
    3.8/5Good! (26 reviews)
    Days Inn and Suites by Wyndham Sikeston

Pet Friendly Southeast Missouri Hotels

  • Auburn Place Hotel And Suites
    Auburn Place Hotel And Suites
    3265 William St, Cape Girardeau, MO
    The price is $69 per night from Jan 28 to Jan 29
    4.4/5Wonderful! (45 reviews)
    Auburn Place Hotel And Suites
  • Motel 6 Poplar Bluff, MO
    Motel 6 Poplar Bluff, MO
    4101 Highway 67 N, Poplar Bluff, MO
    The price is $65 per night from Jan 28 to Jan 29
    4.1/5Very Good! (21 reviews)
    Motel 6 Poplar Bluff, MO
  • Microtel Inn & Suites by Wyndham Sainte Genevieve
    Microtel Inn & Suites by Wyndham Sainte Genevieve
    21958 Hwy 32, Ste Genevieve, MO
    The price is $67 per night from Feb 1 to Feb 2
    4.1/5Very Good! (10 reviews)
    Microtel Inn & Suites by Wyndham Sainte Genevieve

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