Hotels in Southeast Missouri
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Top Rated Southeast Missouri Hotels
Auburn Place Hotel And Suites
3265 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
46.97 mi from city center
The price is $75 per night
$75
includes taxes & fees
$66 per night
Aug 5 - Aug 6
Guests staying at Auburn Place Hotel And Suites enjoy an indoor pool, a gym, and free WiFi in public areas. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a 24-hour business center, a meeting room, and laundry facilities.
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
54.5 mi from city center
The price is $74 per night
$74
includes taxes & fees
$65 per night
Aug 7 - Aug 8
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
Breakfast included
Pet friendly
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
The price is $63 per night
$63
includes taxes & fees
$55 per night
Aug 4 - Aug 5
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Breakfast included
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Free Cancellation
Reserve now, pay when you stay
29.15 mi from city center
The price is $78 per night
$78
includes taxes & fees
$73 per night
Jul 30 - Jul 31
Guests staying at Motel 6 Poplar Bluff, MO enjoy free WiFi in public areas, laundry facilities, and a vending machine. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with tours/tickets and luggage storage.
Pet friendly
Parking included
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
46.79 mi from city center
The price is $76 per night
$76
includes taxes & fees
$67 per night
Jul 31 - Aug 1
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Breakfast included
Pet friendly
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
The price is $127 per night
$127
includes taxes & fees
$112 per night
Aug 1 - Aug 2
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a spa tub, meeting rooms, and a conference center.
Pool
Hot Tub
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
45.7 mi from city center
The price is $95 per night
$95
includes taxes & fees
$88 per night
Jul 28 - Jul 29
At La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, laundry facilities, and a vending machine.
Pool
Parking included
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
54.15 mi from city center
The price is $107 per night
$107
includes taxes & fees
$94 per night
Aug 4 - Aug 5
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
47.07 mi from city center
The price is $71 per night
$71
includes taxes & fees
$63 per night
Aug 1 - Aug 2
Pear Tree Inn Cape Girardeau Near the Medical Center features free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out and a TV in a common area.
Pool
Pet friendly
Silo Farm Haus- located in the heart of wine country!
41.04 mi from city center
The price is $352 per night
$352
includes taxes & fees
$331 per night
Jul 28 - Jul 29
Guests staying at this farm stay enjoy features like a water park.
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
3253 William Street, Cape Girardeau, MO
Free Cancellation
47.02 mi from city center
The price is $116 per night
$116
includes taxes & fees
$103 per night
Aug 25 - Aug 26
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
54.11 mi from city center
The price is $88 per night
$88
includes taxes & fees
$76 per night
Aug 1 - Aug 2
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include free WiFi in public areas, a spa tub, and a business center.
Pool
Hot Tub
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check Southeast Missouri hotel room prices by star rating
4 Star Hotels
2 properties
3 Star Hotels
41 properties
Cheap Southeast Missouri hotels options
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane, Sikeston, MO
The price is $63 per night from Aug 14 to Aug 15
$63
includes taxes & fees
$55 per night
Aug 14 - Aug 15
8.2/10 Very Good! (561 reviews)
Auburn Place Hotel And Suites
3265 William St, Cape Girardeau, MO
The price is $75 per night from Aug 5 to Aug 6
$75
includes taxes & fees
$66 per night
Aug 5 - Aug 6
8.6/10 Excellent! (1,001 reviews)
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
The price is $76 per night from Jul 31 to Aug 1
$76
includes taxes & fees
$67 per night
Jul 31 - Aug 1
8.8/10 Excellent! (1,002 reviews)
Microtel Inn & Suites by Wyndham Sainte Genevieve
21958 Hwy 32, Ste Genevieve, MO
The price is $93 per night from Aug 25 to Aug 26
$93
includes taxes & fees
$84 per night
Aug 25 - Aug 26
8.8/10 Excellent! (515 reviews)
New Orleans Inn Portageville
600 US-61, Portageville, MO
The price is $57 per night from Aug 11 to Aug 12
$57
includes taxes & fees
$52 per night
Aug 11 - Aug 12
8/10 Very Good! (474 reviews)
Quality Inn Farmington
1400 W Liberty St, Farmington, MO
The price is $62 per night from Aug 25 to Aug 26
$62
includes taxes & fees
$54 per night
Aug 25 - Aug 26
7.8/10 Good! (719 reviews)
Southeast Missouri Hotels
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Great selection of hotels in Southeast Missouri
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Southeast Missouri hotels essential information
Accommodation | 573 hotels |
|---|---|
Lowest Price | $57 |
Highest Price | $352 |
Popular hotels | Auburn Place Hotel And Suites, Days Inn and Suites by Wyndham Sikeston, Baymont Inn and Suites by Wyndham Farmington, MO, Motel 6 Poplar Bluff, MO, Pear Tree Inn Cape Girardeau West, Drury Plaza Hotel Cape Girardeau Conference Center, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Drury Inn & Suites Sikeston, MO, Pear Tree Inn Cape Girardeau Near the Medical Center, Silo Farm Haus- located in the heart of wine country!, Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, Pear Tree Inn Sikeston |
Recent Reviews
Motel 6 Poplar Bluff, MO
5/5 Excellent
Earlier Check In Time
"I think there should be an earlier check in time than 4PM. Most Hotels are 2 or 3 PM. For this reason I will choose another hotel next time."
A verified traveler stayed at Motel 6 Poplar Bluff, MO
Posted 3 days ago
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