Compare Seneca Guest House Rentals

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Guest Houses in Seneca

Peaceful Lakefront Getaway Close to Clemson

Peaceful Lakefront Getaway Close to Clemson

Townville SC
At this guesthouse, guests have access to an arcade/game room, laundry facilities, and barbecue grills.
Free WiFi
Air conditioning
Chauga River - The Guest House - Private - Secluded

Chauga River - The Guest House - Private - Secluded

Mountain Rest SC
At this guesthouse, guests have access to features like laundry facilities. This smoke-free guesthouse also has barbecue grills.
Air conditioning
Parking available
Spectacular Spacious 3 Bdrm/2 Full Bath Escape near Clemson

Spectacular Spacious 3 Bdrm/2 Full Bath Escape near Clemson

Central SC
Guests staying at this guesthouse have access to laundry facilities, barbecue grills, and a garden.
Free WiFi
Air conditioning
BEAUTIFUL GUEST HOUSE NEAR THE SMOKEY MOUNTAINS. PROPERY IS FOR VACATION.

BEAUTIFUL GUEST HOUSE NEAR THE SMOKEY MOUNTAINS. PROPERY IS FOR VACATION.

Sapphire NC
At this guesthouse, guests have access to features like laundry facilities.
Air conditioning
Parking available
The Inn at Southern Oaks located in Historic Lavonia, GA, close to Lake Hartwell

The Inn at Southern Oaks located in Historic Lavonia, GA, close to Lake Hartwell

Lavonia GA
At this guesthouse, guests have access to features like local meal delivery service. This smoke-free guesthouse also has barbecue grills.
Free WiFi
Air conditioning
Don't see what you're looking for?
See all available properties in Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Seneca

    Lakeside Lodge Clemson

    Lakeside Lodge Clemson

    13500 Clemson Blvd Seneca SC
    $123 nightly
    The price is $135 total per night from Jul 5 to Jul 6
    $135 total
    Jul 5 - Jul 6
    Total with taxes and fees
    9/10 Wonderful! (1,000 reviews)
    Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

    Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

    299 Outpost Rd Seneca SC
    $141 nightly
    The price is $155 total per night from Aug 2 to Aug 3
    $155 total
    Aug 2 - Aug 3
    Total with taxes and fees
    9.8/10 Exceptional! (86 reviews)
    Quality Inn Seneca Clemson Area US-123

    Quality Inn Seneca Clemson Area US-123

    226 Hi Tech Rd Seneca SC
    $86 nightly
    The price is $94 total per night from Jul 26 to Jul 27
    $94 total
    Jul 26 - Jul 27
    Total with taxes and fees
    8/10 Very Good! (722 reviews)

Seneca Guest Houses essential information

Accommodation
4 Guest Houses
Lowest Price
$94
Highest Price
$155
Popular accommodation
Peaceful Lakefront Getaway Close to Clemson, Chauga River - The Guest House - Private - Secluded, Spectacular Spacious 3 Bdrm/2 Full Bath Escape near Clemson, BEAUTIFUL GUEST HOUSE NEAR THE SMOKEY MOUNTAINS. PROPERY IS FOR VACATION., The Inn at Southern Oaks located in Historic Lavonia, GA, close to Lake Hartwell

More to Explore