Hotels in Seneca
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Top Rated Seneca Hotels
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Free Cancellation
Reserve now, pay when you stay
5.27 mi from city center
$123 nightly
The price is $135 total per night
$135 total
Dec 25 - Dec 26
Total with taxes and fees
Guests staying at Lakeside Lodge Clemson enjoy a 24-hour gym, free WiFi in public areas, and a hot tub. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with securing valuables and concierge services. Additional amenities include a seasonal outdoor pool and a banquet hall.
Pool
Hot Tub
Tru by Hilton Seneca Clemson
13050 Clemson Blvd Seneca SC
Free Cancellation
Reserve now, pay when you stay
5.12 mi from city center
$98 nightly
The price is $107 total per night
$107 total
Dec 30 - Dec 31
Total with taxes and fees
Tru by Hilton Seneca Clemson features a gym, free WiFi in public areas, and a business center. You can take advantage of free parking if you drive. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include coffee/tea in a common area, an arcade/game room, and laundry facilities.
Breakfast included
Pet friendly
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Free Cancellation
Reserve now, pay when you stay
0.16 mi from city center
$79 nightly
The price is $87 total per night
$87 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Quality Inn Seneca Clemson Area US-123 enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. Free parking is available if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include coffee/tea in a common area, a water dispenser, and a vending machine.
Pool
Breakfast included
Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
Free Cancellation
Reserve now, pay when you stay
1.15 mi from city center
$119 nightly
The price is $131 total per night
$131 total
Dec 28 - Dec 29
Total with taxes and fees
Hampton Inn & Suites Seneca-Clemson Area features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
Free Cancellation
Reserve now, pay when you stay
1.92 mi from city center
$73 nightly
The price is $80 total per night
$80 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of Days Inn by Wyndham Seneca / Clemson Area enjoy access to free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. A stay here includes free parking. The 24-hour front desk has staff always at the ready. Additional amenities include free newspapers, laundry facilities, and a vending machine.
Pool
Breakfast included
Fairfield Inn & Suites Seneca Clemson Univ Area
800 BYPASS 123 Seneca SC
Free Cancellation
Reserve now, pay when you stay
1.08 mi from city center
$115 nightly
The price is $127 total per night
$127 total
Dec 29 - Dec 30
Total with taxes and fees
At Fairfield Inn & Suites Seneca Clemson Univ Area , guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
4.92 mi from city center
$129 nightly
The price is $142 total per night
$142 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
If you drive, take advantage of free parking. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls.
Kitchen
Pet friendly
Best Western Seneca-Clemson
511 Bypass Highway 123 Seneca SC
Free Cancellation
Reserve now, pay when you stay
0.81 mi from city center
$84 nightly
The price is $93 total per night
$93 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Guests of Best Western Seneca-Clemson enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Additional amenities include a computer station, free newspapers, and a vending machine.
Pool
Breakfast included
Fabulous Tiny House with AC in charming Seneca
Seneca SC
3.68 mi from city center
At this cabin, guests have access to barbecue grills.
Pet friendly
Air conditioning
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
Seneca SC
6 mi from city center
At this vacation home, guests have access to an arcade/game room, laundry facilities, and barbecue grills. This family-friendly vacation home also has a garden.
Kitchen
Washer
Fall fun at the cabin! Convenient to Lake Keowee and Clemson
Seneca SC
3.96 mi from city center
Guests staying at this cabin enjoy a gym, an arcade/game room, and laundry facilities. Additional amenities include barbecue grills and a garden.
Kitchen
Washer
Enjoy one of our RV units son less of a headache for you this vacation!
Seneca SC
5.95 mi from city center
$139 nightly
The price is $153 total per night
$153 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
At Enjoy one of our RV units son less of a headache for you this vacation!, guests have access to a garden.
Kitchen
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Seneca hotels options
Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
$73 nightly
The price is $80 total per night from Dec 28 to Dec 29
$80 total
Dec 28 - Dec 29
Total with taxes and fees
6.8/10 (721 reviews)
Best Western Seneca-Clemson
511 Bypass Highway 123 Seneca SC
$84 nightly
The price is $93 total per night from Jan 1 to Jan 2
$93 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
8.2/10 Very Good! (641 reviews)
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
$79 nightly
The price is $87 total per night from Jan 4 to Jan 5
$87 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
7.8/10 Good! (665 reviews)
What's the best place for a stay in Seneca?
What are the best hotels for a stay with my pet in Seneca?
You and your furry companion will find 7 pet-friendly hotels in Seneca for your trip. Quality Inn Seneca Clemson Area US-123 is a pet-friendly hotel with free breakfast, free WiFi, and free parking. You and your pet can also consider Lakeside Lodge Clemson, a pet-friendly hotel with free WiFi, free parking, and a 24-hour fitness center. Tru by Hilton Seneca Clemson is another option, and it's a pet-friendly hotel with free breakfast, free WiFi, and free parking.
What are some favorite hotels in central Seneca?
These are some of our travelers' favorite hotels in downtown Seneca:
- Quality Inn Seneca Clemson Area US-123 is a hotel offering free breakfast, free WiFi, and free parking.
- Best Western Seneca-Clemson is a hotel offering free breakfast, free WiFi, and free parking.
Stop in at the coffeehouses in family-friendly Seneca, and then enjoy the local attractions such as the sporting events.
What are some favorite hotels near Keowee Reservoir?
Get out into nature at this local spot, located 3.8 mi from the heart of Seneca. There are 68 hotels within 5 miles of Keowee Reservoir, giving you plenty of options to choose from including:
- Hampton Inn & Suites Seneca-Clemson Area, SC: Located 2.6 mi away, this hotel has free breakfast, free WiFi, and free parking.
- Quality Inn Seneca US-123: Located 3.7 mi away, this hotel has free breakfast, free WiFi, and free parking.
- Tru by Hilton Seneca Clemson: Located 3.9 mi away, this hotel has free breakfast, free WiFi, and free parking.
Seneca hotels essential information
Accommodation | 1,646 hotels |
|---|---|
Lowest Price | $80 |
Highest Price | $153 |
Popular hotels | Lakeside Lodge Clemson, Tru by Hilton Seneca Clemson, Quality Inn Seneca Clemson Area US-123, Hampton Inn & Suites Seneca-Clemson Area, Days Inn by Wyndham Seneca / Clemson Area, Fairfield Inn & Suites Seneca Clemson Univ Area , Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy, Best Western Seneca-Clemson, Fabulous Tiny House with AC in charming Seneca, 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water., Fall fun at the cabin! Convenient to Lake Keowee and Clemson, Enjoy one of our RV units son less of a headache for you this vacation! |
Recent Reviews
Hampton Inn & Suites Seneca-Clemson Area
5/5 Excellent
"Rooms are clean, nice place"
A verified traveler stayed at Hampton Inn & Suites Seneca-Clemson Area
Posted 2 days ago
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