Hotels in Seneca

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  • Apr 2 - Apr 3
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    Check prices in Seneca for tonight, Apr 2 - Apr 3
  • Apr 3 - Apr 4
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    Check prices in Seneca for tomorrow night, Apr 3 - Apr 4

Top Rated Seneca Hotels

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC, 29678
Free Cancellation
Reserve now, pay when you stay
5.27 mi from city center
The price is $109 per night
$109
per night
Apr 3 - Apr 4
Guests staying at Lakeside Lodge Clemson enjoy a 24-hour gym, free WiFi in public areas, and a spa tub. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with concierge services, and answer any questions about the accommodations. This hotel also has a seasonal outdoor pool.
Quality Inn Seneca US-123

Quality Inn Seneca US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC, 29678
Free Cancellation
Reserve now, pay when you stay
0.16 mi from city center
The price is $81 per night
$81
per night
May 1 - May 2
Guests of Quality Inn Seneca US-123 enjoy access to free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. Free parking is available if you drive. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free hotel also has a water dispenser.
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd, Seneca, SC, 29678
Free Cancellation
Reserve now, pay when you stay
5.12 mi from city center
The price is $109 per night
$109
per night
May 1 - May 2
Tru by Hilton Seneca Clemson features a gym, free WiFi in public areas, and a business center. You can take advantage of free parking if you drive. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include coffee/tea in a common area, laundry facilities, and a convenience store.
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123, Seneca, SC, 29678
Free Cancellation
Reserve now, pay when you stay
0.81 mi from city center
The price is $93 per night
$93
per night
Apr 23 - Apr 24
Guests of Best Western Seneca-Clemson enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Additional amenities include a computer station and free newspapers.
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street, Seneca, SC, 29678
Free Cancellation
Reserve now, pay when you stay
1.15 mi from city center
The price is $124 per night
$124
per night
Apr 9 - Apr 10
Hampton Inn & Suites Seneca-Clemson Area features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 out of 5
800 BYPASS 123, Seneca, SC, 29678
Free Cancellation
Reserve now, pay when you stay
1.08 mi from city center
The price is $129 per night
$129
per night
Apr 3 - Apr 4
At Fairfield Inn & Suites Seneca Clemson Univ Area , guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include coffee/tea in a common area, a meeting room, and a computer station.
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd, Seneca, SC, 29678-1142
Free Cancellation
Reserve now, pay when you stay
1.92 mi from city center
The price is $68 per night
$68
per night
Apr 28 - Apr 29
Guests of Days Inn by Wyndham Seneca / Clemson Area enjoy access to free WiFi in public areas, conference space, and a business center. A stay here includes free parking. The 24-hour front desk has staff always at the ready. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and free newspapers.
Boutique hotel in historic downtown Seneca (Room #4)

Boutique hotel in historic downtown Seneca (Room #4)

Seneca, SC
0.03 mi from city center
The price is $130 per night
$130
per night
Apr 3 - Apr 4
This apartment is a smoke-free apartment building.
Well Appointed Bungalow on Beautiful Horse Farm w/boat parking, close to Clemson

Well Appointed Bungalow on Beautiful Horse Farm w/boat parking, close to Clemson

Seneca, SC
6.85 mi from city center
At this vacation home, guests have access to barbecue grills.
Boutique hotel in historic downtown Seneca (Room #5)

Boutique hotel in historic downtown Seneca (Room #5)

Seneca, SC
0.04 mi from city center
The price is $130 per night
$130
per night
Apr 3 - Apr 4
This apartment is a smoke-free apartment building.
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Seneca, SC
3.96 mi from city center
At this cabin, guests have access to a gym, an arcade/game room, and a garden. This family-friendly cabin also has barbecue grills.
NEW Seneca Creek Hideaway | Hot Tub | Bar & Game Room | Close to Lakes & Clemson

NEW Seneca Creek Hideaway | Hot Tub | Bar & Game Room | Close to Lakes & Clemson

Seneca, SC
3.79 mi from city center
The price is $212 per night
$212
per night
Apr 4 - Apr 5
Guests staying at this cabin enjoy a spa tub, an arcade/game room, and a garden. Friendly staff can provide concierge services, and also offer advice about sightseeing. This smoke-free cabin also has barbecue grills.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Seneca

    Quality Inn Seneca US-123

    Quality Inn Seneca US-123

    226 Hi Tech Rd, Seneca, SC, 29678
    The price is $81 per night from May 1 to May 2
    $81
    per night
    May 1 - May 2
    7.6/10 Good! (416 reviews)

Pet Friendly Seneca Hotels

What's the best place for a stay in Seneca?

What are some of the best hotels for a stay with my family in Seneca?

Book one of the 6 family-friendly hotels in Seneca for your family's vacation. Tru by Hilton Seneca Clemson is a hotel offering free parking, free breakfast, and laundry facilities. Your family can also consider Best Western Seneca-Clemson, a hotel offering free parking, free WiFi, and free cribs.

What are some favorite hotels in central Seneca?

These are some of our travelers' favorite hotels in downtown Seneca:

Stop in at the coffeehouses in family-friendly Seneca, and then enjoy the local attractions such as the sporting events.

What are some favorite hotels near Keowee Reservoir?

Get out into nature at this local spot, located 3.8 mi from the heart of Seneca. There are 68 hotels within 5 miles of Keowee Reservoir, giving you plenty of options to choose from including:

Recent Reviews

  • Quality Inn Seneca US-123

    Quality Inn Seneca US-123

    5/5 Excellent
    "For the price it was okay. "
    A verified traveler stayed at Quality Inn Seneca US-123
    Posted 5 days ago
    Quality Inn Seneca US-123

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