Santee Vacation Homes

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Vacation Homes in Santee

Don't see what you're looking for?
See all available properties in Santee
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Santee

    San Diego Marriott La Jolla

    San Diego Marriott La Jolla

    4240 La Jolla Village Dr, La Jolla, CA
    The price is $207 per night from May 11 to May 12
    $207
    includes taxes & fees
    $180 per night
    May 11 - May 12
    8.4/10 Very Good! (1,745 reviews)
    San Diego Mission Bay Resort

    San Diego Mission Bay Resort

    1775 E Mission Bay Dr, San Diego, CA
    The price is $285 per night from May 11 to May 12
    $285
    includes taxes & fees
    $248 per night
    May 11 - May 12
    8.2/10 Very Good! (1,191 reviews)
    The Dana on Mission Bay

    The Dana on Mission Bay

    1710 W Mission Bay Dr, San Diego, CA
    The price is $194 per night from May 11 to May 12
    $194
    includes taxes & fees
    $169 per night
    May 11 - May 12
    8.8/10 Excellent! (3,336 reviews)

Santee Vacation Homes

Book vacation homes in Santee
Next time you take a group getaway top Santee, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Santee vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Santee vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Santee; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Santee rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Santee is sure to be a winner.

Santee Vacation Homes essential information

Accommodation
3803 Vacation Homes
Lowest Price
$194
Highest Price
$623
Popular accommodation
Isthmus Oasis at Belmont Park, 2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay, Beachside Getaway with Rooftop Spa & Parking, Beautiful Normal Heights Living, Best Location in San Diego. 3 Story Spanish Style Home in Heart of North Park, Serene 4 Bedroom with Canyon and Ocean Views, Spacious 4 BR perfect for a big group near 🌆🐘🐳🏖 🌈+ 2 car garage + central A/C , Cozy beach house just one house off from beach and boardwalk, Adorable Spanish style casita in fantastic area of Historic North Park