San Francisco Vacation Homes

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Featured Vacation Homes in San Francisco

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in San Francisco

    Hotel Riu Plaza Fisherman's Wharf

    Hotel Riu Plaza Fisherman's Wharf

    2500 Mason St San Francisco CA
    $165 nightly
    The price is $194 total per night from Jul 5 to Jul 6
    $194 total
    Jul 5 - Jul 6
    Total with taxes and fees
    9/10 Wonderful! (7,511 reviews)
    Handlery Union Square Hotel

    Handlery Union Square Hotel

    351 Geary St San Francisco CA
    $172 nightly
    The price is $202 total per night from Jul 5 to Jul 6
    $202 total
    Jul 5 - Jul 6
    Total with taxes and fees
    8.8/10 Excellent! (3,260 reviews)
    Hyatt Regency San Francisco

    Hyatt Regency San Francisco

    5 Embarcadero Center San Francisco CA
    $238 nightly
    The price is $280 total per night from Jul 12 to Jul 13
    $280 total
    Jul 12 - Jul 13
    Total with taxes and fees
    9.2/10 Wonderful! (2,334 reviews)

San Francisco Vacation Homes

Book vacation homes in San Francisco
Next time you take a group getaway top San Francisco, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of San Francisco vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every San Francisco vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in San Francisco; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a San Francisco rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to San Francisco is sure to be a winner.

San Francisco Vacation Homes essential information

Accommodation
346 Vacation Homes
Lowest Price
$194
Highest Price
$649
Popular accommodation
622- 1 bedroom 1 bathroom suite with TV, Private Bath & Kitchenette, Pacific Heights Grand Elegant Studio, Cozy studio close to beach, Modern 3BR 2BA / Family Friendly / Smart Toilets / EV Charging / SFO, Cheerful Studio w/ View, Steps from Dolores Park, Wing of San Francisco(旧金山之翼)2 BRooms for 1–4 people, Vintage San Francisco Bay Area Home, @ Marbella Lane - Natural BayView Escape |Near SFO, Pacific Heights Grand Victorian Top Floor Kitchen

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