Compare Lower Matecumbe Key Villas

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Featured Villas in Lower Matecumbe Key

The Islands of Islamorada

The Islands of Islamorada

4 out of 5
82779 Old Hwy Islamorada FL
$658 nightly
The price is $740 total per night
$740 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Guests staying at The Islands of Islamorada enjoy access to 2 outdoor pools, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff can help with tours or tickets, and provide local restaurant recommendations. Other amenities at this beach villa include a hot tub, a garden, and barbecue grills.
Pool
Hot Tub
Villa del Sol - Sunset Views, Kayaks, 2/2.5 - Slip Available/Ramp/Free Pkg

Villa del Sol - Sunset Views, Kayaks, 2/2.5 - Slip Available/Ramp/Free Pkg

2 out of 5
Duck Key FL
At this villa, guests have access to features like laundry facilities.
Washer
Dryer
Seas the Keys Getaway

Seas the Keys Getaway

Duck Key FL
This villa features a gym and laundry facilities.
Pool
Kitchen
Charming 3-bedroom villa with WiFi, AC in welcoming Marathon

Charming 3-bedroom villa with WiFi, AC in welcoming Marathon

Marathon FL
Guests staying at this villa enjoy a hot tub, laundry facilities, and barbecue grills. This smoke-free villa also has a garden.
Villa 5087 on Duck Key Boat Slip Available - 2BD 2.5BA

Villa 5087 on Duck Key Boat Slip Available - 2BD 2.5BA

Duck Key FL
$583 nightly
The price is $647 total per night
$647 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At this villa, guests have access to features like laundry facilities.
DUPLEX IN DUCK KEY 3/2 W/90' Private Dock, Trailer Storage included

DUPLEX IN DUCK KEY 3/2 W/90' Private Dock, Trailer Storage included

Marathon FL
At this villa, guests have access to features like laundry facilities.
Pool
Kitchen
Villa 5021 on Duck Key Boat Slip Available - 2BD 2.5BA

Villa 5021 on Duck Key Boat Slip Available - 2BD 2.5BA

Duck Key FL
$577 nightly
The price is $641 total per night
$641 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At this villa, guests have access to features like laundry facilities.
Kitchen
Washer
Waterfront retreat with balcony views, kayak, SUP, central AC & washer/dryer

Waterfront retreat with balcony views, kayak, SUP, central AC & washer/dryer

Duck Key FL
At this villa, guests have access to features like laundry facilities. This beach villa also has a garden.
Kitchen
Washer
Waterfront House with Boat Dock

Waterfront House with Boat Dock

5 out of 5
213 Aberdeen Ct Tavernier FL
At this villa, guests have access to a children's pool, laundry facilities, and a picnic area. Free parking is included with your stay. A multilingual staff is on hand to help with luggage storage, and offer sightseeing advice.
Kitchen
Washer
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Lower Matecumbe Key

    Matecumbe Resort

    Matecumbe Resort

    76261 Overseas Hwy Islamorada FL
    $157 nightly
    The price is $177 total per night from Jan 14 to Jan 15
    $177 total
    Jan 14 - Jan 15, 2026
    Total with taxes and fees
    8.8/10 Excellent! (85 reviews)
    Chesapeake Beach Resort

    Chesapeake Beach Resort

    83409 Overseas Hwy Islamorada FL
    $211 nightly
    The price is $238 total per night from Jan 6 to Jan 7
    $238 total
    Jan 6 - Jan 7, 2026
    Total with taxes and fees
    9.2/10 Wonderful! (1,598 reviews)
    Lime Tree Bay Resort

    Lime Tree Bay Resort

    68500 Overseas Hwy Long Key FL
    $182 nightly
    The price is $205 total per night from Jan 15 to Jan 16
    $205 total
    Jan 15 - Jan 16, 2026
    Total with taxes and fees
    9.2/10 Wonderful! (1,117 reviews)

Luxury Villas

Book luxury villas in Lower Matecumbe Key
There are plenty of ways to up your vacation game, but one of the best is by staying in a luxury villa in Lower Matecumbe Key. Villas, with their thoughtful layout and elegant décor, let you travel in style. They come in a variety of sizes and offer a great experience, whether you’re traveling on your own or with a group of friends. Orbitz has fantastic deals on villas in Lower Matecumbe Key, so book one now. You’ll feel like a million bucks before you even check in.

Spacious luxury villas in Lower Matecumbe Key
You won’t have a problem finding your own space in Lower Matecumbe Key. If you’re traveling in a group, go for a three-bedroom or larger villa; separate bedrooms can make it that much easier to keep the peace, especially when you’re all staying in one house. You can also explore Lower Matecumbe Key on your own and use a one-bedroom villa as your home base.

A top-end villa experience in Lower Matecumbe Key rivals that of a luxury resort. Float in a swimming pool with an elaborate mosaic bottom, work out in your own gym, and let the daily housekeeping staff clean up after you while a private chef whips up one delicious meal after another. This is the life!

Lower Matecumbe Key Villas essential information

Accommodation
85 Villas
Lowest Price
$177
Highest Price
$740
Popular accommodation
The Islands of Islamorada, Villa del Sol - Sunset Views, Kayaks, 2/2.5 - Slip Available/Ramp/Free Pkg, Seas the Keys Getaway, Charming 3-bedroom villa with WiFi, AC in welcoming Marathon, Villa 5087 on Duck Key Boat Slip Available - 2BD 2.5BA, DUPLEX IN DUCK KEY 3/2 W/90' Private Dock, Trailer Storage included, Villa 5021 on Duck Key Boat Slip Available - 2BD 2.5BA, Waterfront retreat with balcony views, kayak, SUP, central AC & washer/dryer, Waterfront House with Boat Dock

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