Beginning of main content

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Vacation Homes in Knoxville

Lenoir City Cottage
Lenoir City Cottage
Lenoir City, TN
At this vacation home, guests have access to a garden.
Sunny and Cozy Room!
Sunny and Cozy Room!
Knoxville, TN
$50
This vacation home is a smoke-free vacation home.
Vol's Corner 1 Summar
Vol's Corner 1 Summar
Knoxville, TN
This vacation home is a smoke-free vacation home.
Peaceful Country Setting on a Working Horsefarm
Peaceful Country Setting on a Working Horsefarm
Lenoir City, TN
$115
Guests staying at this vacation home have access to a garden and barbecue grills.
A Mother--in-law Suite
A Mother--in-law Suite
Knoxville, TN
This vacation home is a smoke-free vacation home.
Discounts. Weekly & Monthly. 4 wks for the Price of 3
Discounts. Weekly & Monthly. 4 wks for the Price of 3
Knoxville, TN
$109
This vacation home is a smoke-free vacation home.
Wow! 3500 Sqft 4 Bedroom Peaceful Private Acre+ Retreat! Close to Downtown & UT
Wow! 3500 Sqft 4 Bedroom Peaceful Private Acre+ Retreat! Close to Downtown & UT
Knoxville, TN
This vacation home features a spa tub and barbecue grills.
Historic Mid-century Modern Gem
Historic Mid-century Modern Gem
Knoxville, TN
At this vacation home, guests have access to a garden.
Discounts. Weekly & Monthly. 4 Wks for the Price of 3
Discounts. Weekly & Monthly. 4 Wks for the Price of 3
Knoxville, TN
This vacation home is a smoke-free vacation home.
Map

Knoxville Vacation Homes

Book vacation homes in Knoxville
Next time you take a group getaway top Knoxville, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Knoxville vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Knoxville vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Knoxville; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Knoxville rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Knoxville is sure to be a winner.

Hotel Options in Knoxville

See all 302 Properties in Knoxville
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.