Guadalupe Vacation Homes

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Featured Vacation Homes in Guadalupe

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Guadalupe

    Cottage Inn By The Sea

    Cottage Inn By The Sea

    2351 Price St Pismo Beach CA
    $105 nightly
    The price is $120 total per night from Jan 5 to Jan 6
    $120 total
    Jan 5 - Jan 6, 2026
    Total with taxes and fees
    9/10 Wonderful! (1,170 reviews)
    SeaCrest OceanFront Hotel

    SeaCrest OceanFront Hotel

    2241 Price Street Pismo Beach CA
    $149 nightly
    The price is $171 total per night from Jan 4 to Jan 5
    $171 total
    Jan 4 - Jan 5, 2026
    Total with taxes and fees
    9/10 Wonderful! (1,609 reviews)
    Oxford Suites Pismo Beach

    Oxford Suites Pismo Beach

    651 Five Cities Dr Pismo Beach CA
    $119 nightly
    The price is $136 total per night from Dec 21 to Dec 22
    $136 total
    Dec 21 - Dec 22
    Total with taxes and fees
    8.8/10 Excellent! (1,681 reviews)

Guadalupe Vacation Homes

Book vacation homes in Guadalupe
Next time you take a group getaway top Guadalupe, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Guadalupe vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Guadalupe vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Guadalupe; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Guadalupe rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Guadalupe is sure to be a winner.

Guadalupe Vacation Homes essential information

Accommodation
424 Vacation Homes
Lowest Price
$120
Highest Price
$694
Popular accommodation
Escape to a Coastal Retreat: Modern 5-Star Beachfront Home w/ 360 Ocean Views!, WALK to Beach, Pier and Downtown - Parking - BBQ - View, Breathtaking Ocean and Beach Views, BEACHFRONT with Spa , Enjoy the big ocean views, hear the waves crashing, enjoy the coastal vibe. , Happyfam Country Home By Coast, Hot Tub, Fire Pit, Pet Friendly, Walk to Bell St, Pet friendly. 1 mi to beach. Not a house share. , Private in town house with HUGE yard. Pet Friendly

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