$79 Cheap flights to Santo Domingo

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Cheap flights to Santo Domingo from $79 One Way, $164 Round Trip

$164 return flights and $79 one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

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Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIAQuitoJune 26 to July 2$500
YYZQuitoJune 26 to July 24$554
LAXQuitoJune 28 to August 4$616
CCSQuitoJune 28 to July 7$727
JFKQuitoJune 28 to June 30$744
JFKQuitoJune 28 to June 30$744
MADQuitoJune 26 to July 16$1,113
LHRQuitoJune 28 to September 26$1,597
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Santo Domingo Accommodation Deals

Hilton Colon Quito

Hilton Colon Quito

4.5 out of 5
Amazonas N 1914 Y Patria Avenida 1 Quito
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Jul 5 to Jul 6
$97 total
Jul 5 - Jul 6
Book a stay at this luxury hotel in Quito. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (477 reviews)
"Very good service"

Reviewed on May 31, 2026

Opens in a new windowHilton Colon Quito
Hotel Plaza Grande

Hotel Plaza Grande

5 out of 5
Garcia Moreno N5-16 Y Chile Quito Pichincha
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $201 total per night from Jun 29 to Jun 30
$201 total
Jun 29 - Jun 30
Book a stay at this luxury hotel in Quito. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (249 reviews)
"Perfectly located right in the heart of Quito on Independence Plaza, yet very private and quiet. In a classic older building, so beautifully finished and wonderfully furnished. Rooms are luxurious, spacious and very comfortable. I stayed twice, and each room was fantastic. Just steps away are great ..."

Reviewed on Jun 21, 2026

Opens in a new windowHotel Plaza Grande
Hotel Reina Isabel

Hotel Reina Isabel

3.5 out of 5
Av. Amazonas N23-44 y Veintimilla Quito Pichincha
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Jul 23 to Jul 24
$76 total
Jul 23 - Jul 24
Book a stay at this business-friendly hotel in Quito. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
"The hotel is clean and the staff are really very helpful and friendly (reception, housekeeping, restaurant, etc.). The restaurant is very good."

Reviewed on Jun 15, 2026

Opens in a new windowHotel Reina Isabel
Save an average of 15% on thousands of hotels when you're signed in
Hotel San Francisco de Quito

Hotel San Francisco de Quito

3 out of 5
Sucre Oe 3-17 y Guayaquil Quito
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $75 total per night from Jun 28 to Jun 29
$75 total
Jun 28 - Jun 29
Book a stay at this business-friendly hotel in Quito. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (476 reviews)
"This hotel was gorgeous, rooms were clean and spacious. They offered airport service via taxi for a fee, which was reasonable and greatly appreciated. This hotel is centrally located and walking distance to the grand plaza and several other spots we wanted to see. Staff were helpful and we loved ..."

Reviewed on Jun 19, 2026

Opens in a new windowHotel San Francisco de Quito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Santo Domingo

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First-Timers

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Ports and Play

Be sure to check our cruise page for free shore excursions, onboard spending, balcony upgrades and other perks. Orbitz offers last-minute, luxury, weekend and summer cruises. You can even designate which port you want to sail from and pre-book on-shore activities. Get there on the cheap with discounts on flights to Santo Domingo and Santo Domingo flights. Get more bang for your travel buck at Orbitz.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.