$38 Cheap flights to Florence County

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Top places to visit in Florence County

A historic brick building with arched windows and a river in the foreground.
FlightsFlights
FlightsFlights

Florence

Florence
A sunset over a forested landscape with a river and a parking lot.
FlightsFlights
FlightsFlights

Lake City

Lake City

Cheap flights to Florence County from $38 One Way, $85 Round Trip

$85 return flights and $38 one-way flights to Florence County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Oct 25 - Thu, Oct 29
CAK
Akron
MYR
Myrtle Beach
$85 Roundtrip, found 17 hours ago
$85
Roundtrip
found 17 hours ago
Select Allegiant Air flight, departing Sun, Oct 25 from Akron to Myrtle Beach, returning Thu, Oct 29, priced at $85 found 17 hours ago
Sun, Oct 25 - Fri, Nov 6
PIT
Pittsburgh
MYR
Myrtle Beach
$111 Roundtrip, found 3 days ago
$111
Roundtrip
found 3 days ago
Select Allegiant Air flight, departing Sun, Oct 25 from Pittsburgh to Myrtle Beach, returning Fri, Nov 6, priced at $111 found 3 days ago
Fri, Jan 8 - Fri, Jan 15
CAK
Akron
MYR
Myrtle Beach
$112 Roundtrip, found 1 hour ago
$112
Roundtrip
found 1 hour ago
Select Breeze Airways flight, departing Fri, Jan 8 from Akron to Myrtle Beach, returning Fri, Jan 15, priced at $112 found 1 hour ago
Thu, Jan 21 - Thu, Jan 28
SWF
Newburgh
MYR
Myrtle Beach
$112 Roundtrip, found 6 days ago
$112
Roundtrip
found 6 days ago
Select Allegiant Air flight, departing Thu, Jan 21 from Newburgh to Myrtle Beach, returning Thu, Jan 28, priced at $112 found 6 days ago
Thu, Jan 21 - Thu, Jan 28
BDL
Hartford
MYR
Myrtle Beach
$122 Roundtrip, found 3 hours ago
$122
Roundtrip
found 3 hours ago
Select Breeze Airways flight, departing Thu, Jan 21 from Hartford to Myrtle Beach, returning Thu, Jan 28, priced at $122 found 3 hours ago
Thu, Jan 7 - Sun, Jan 10
FLL
Fort Lauderdale
MYR
Myrtle Beach
$132 Roundtrip, found 3 hours ago
$132
Roundtrip
found 3 hours ago
Select Breeze Airways flight, departing Thu, Jan 7 from Fort Lauderdale to Myrtle Beach, returning Sun, Jan 10, priced at $132 found 3 hours ago
Mon, Jan 25 - Sun, Jan 31
HPN
White Plains
MYR
Myrtle Beach
$168 Roundtrip, found 1 day ago
$168
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Mon, Jan 25 from White Plains to Myrtle Beach, returning Sun, Jan 31, priced at $168 found 1 day ago
Mon, Jan 11 - Sun, Jan 17
HPN
White Plains
MYR
Myrtle Beach
$173 Roundtrip, found 2 days ago
$173
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Mon, Jan 11 from White Plains to Myrtle Beach, returning Sun, Jan 17, priced at $173 found 2 days ago
Sun, Nov 1 - Thu, Nov 5
HPN
White Plains
MYR
Myrtle Beach
$175 Roundtrip, found 2 days ago
$175
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Sun, Nov 1 from White Plains to Myrtle Beach, returning Thu, Nov 5, priced at $175 found 2 days ago
Mon, Jan 11 - Sun, Jan 17
HPN
White Plains
MYR
Myrtle Beach
$178 Roundtrip, found 2 days ago
$178
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Mon, Jan 11 from White Plains to Myrtle Beach, returning Sun, Jan 17, priced at $178 found 2 days ago
Sat, Oct 24 - Wed, Oct 28
BOS
Boston
MYR
Myrtle Beach
$216 Roundtrip, found 1 day ago
$216
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Oct 24 from Boston to Myrtle Beach, returning Wed, Oct 28, priced at $216 found 1 day ago
Sat, Oct 31 - Tue, Nov 3
BOS
Boston
MYR
Myrtle Beach
$293 Roundtrip, found 3 days ago
$293
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Oct 31 from Boston to Myrtle Beach, returning Tue, Nov 3, priced at $293 found 3 days ago
Loading

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
FLLMyrtle BeachSeptember 19 to September 28$188
SWFMyrtle BeachSeptember 20 to September 24$199
TPAMyrtle BeachSeptember 19 to September 24$211
ALBMyrtle BeachSeptember 18 to September 21$300
LGAMyrtle BeachSeptember 19 to September 25$411
BOSMyrtle BeachSeptember 19 to September 21$423
EWRMyrtle BeachSeptember 18 to September 21$556
DALMyrtle BeachSeptember 18 to September 21$609
EWRFlorenceSeptember 18 to September 21$629
EWRFlorenceSeptember 18 to September 21$629
LGAFlorenceSeptember 18 to September 21$629
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Florence County Accommodation Deals

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Sep 20 to Sep 21
$100 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Opens in a new windowPark Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Sep 16 to Sep 17
$72 total
Sep 16 - Sep 17
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,727 reviews)
"."

Reviewed on Sep 15, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Sep 27 to Sep 28
$100 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Opens in a new windowQuality Inn & Suites Florence Civic Center
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundable
$105 nightly
The price is $118 total per night from Oct 11 to Oct 12
$118 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,364 reviews)
"I"

Reviewed on Sep 14, 2026

Opens in a new windowComfort Inn & Suites Florence Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Florence County

Orbitz uses cutting edge mobile technology to help get you the best deals on Florence County flights. We offer guaranteed low prices on air tickets that can be combined with hotels and car rentals to save you even more money.

Find Cheap Florence County Flights And Hotel Rooms Using Our Mobile App

Orbitz not only guarantees low prices for flights to Florence County, we also offer Mobile Steals on our Orbitz on the Go mobile app where you can find great mobile-only deals on hotel rooms in the area.

Use the Orbitz Flight Matrix To Save Big On Car Rental

Discount flights to Florence County can be combined with car rental to get you additional savings. Just use our Flight Matrix to see how your budget air ticket can be combined with a car rental to make your trip not only inexpensive but also more convenient.

Use Multiple Airlines To Ensure You Get The Best Deal

Orbitz allows you to use multiple airlines for flights to Florence County. By using a combination of airlines for discount flights you are guaranteed to get the lowest fares each way and get the schedule that is most convenient for you.

Store Your Frequent Flyer Information on Orbitz For Easy Access

Booking with Orbitz will still allow you to apply miles for flights to Florence County to your frequent flyer program. Not only that, but your frequent flyer information will be safely stored on our website, so it will be easy to access the next time you book a discount air ticket with Orbitz.

Frequently asked questions

What is the best airport to fly to in Florence County?
There's one main entry point for this region — Florence Regional Airport (FLO). Book your flights to this popular gateway and see all that Florence County has to offer.
How much is a flight to Florence County?
Round-trip prices dropped as low as $85 this week to Florence County, and reached a high of $629. Passengers flying out of Akron (CAK) managed to land one-way flights from just $38.
How to book the cheapest flight to Florence County?
Snapping up cheap flights to Florence County is as simple as booking your ticket with Orbitz. But if you'd love to make sure you're nabbing the best flight deals around, here are a few tips worth following:

  • Depending on your place of departure, choose the 'Nearby airports' function (located under the departure and arrival options). At times, other departure points will have cheaper fares.
  • Also, click on the 'Show flexible dates' link to view the prices for days around your chosen departure. You may be able to pick up cheaper flight deals if you're flexible with your schedule.
  • You can also use the 'Show options' link to filter results for your preferred carrier, seating class, nonstop flights and refundable flights. Under 'Sort & Filter' to the left, you can even choose the time of day you want to fly.
  • Once you've sorted out your travel dates, don't delay booking. Prices generally increase as the departure date nears.
  • Think about bundling your hotels, flights and car rental into an Orbitz package — the more you book, the more you save.
  • Flying during busier seasons means steep airfares. If possible, plan your trip outside of popular periods, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Florence County?
Generally speaking, January is the cheapest time to purchase your plane ticket. This is closely followed by February and August. Bear this in mind while you search for a cheap flight to Florence County.
What day of the week is the cheapest to book a flight to Florence County?
If you're after inexpensive fares to Florence County, the best days to make a booking are Tuesdays, Wednesdays and Saturdays. With Orbitz (and some good timing!), an unbeatable flight deal will be all yours.
What is the cheapest day of the week to fly to Florence County?
Based on Orbitz data from 2020, Monday tends to be the best day to nab cheap flights to Florence County. Tuesday also offers budget-friendly airfares, whereas Saturday has the most expensive ticket prices. Although flying out at the weekend can be more suitable, you'll have more money in your pocket to play with if you jet out early in the week.
What is the cheapest month to fly to Florence County?
If you're flexible with your travel dates, consider leaving during August. Orbitz data shows that this is generally the best month to take off if you're looking for cheap flights to Florence County. As you would imagine, fares get pricier in June and flights book out quickly.
Which airlines allow free cancellation?
Life changes, and we believe your ticket should be able to do the same. That's why Orbitz makes it a snap to search for airlines with free cancellation and no change fees. Just enter your departure and arrival points and then select "Filter by flexible change policies." How's that for peace of mind?
What do I need for the flight to Florence County?
Whether you're accustomed to flying or you're new to the skies, it's always great to be prepared when you travel. Here are several tips and things to take into consideration:

  • Make sure you've packed your travel documents and identification. For overseas trips, you'll need your passport. When booking your seats, always use the same name, birth date and gender as listed on your current ID.
  • Pack your carry-on bag with snacks and things to keep you busy and watch time whiz by on this medium-haul flight. Wherever possible, hop on the airport's Wi-Fi and transfer your favorite playlist or podcast to your phone or tablet before take off.
  • Never mind what the season is, airplane cabins are often quite cold. Bring a sweater with you on your journey to stay cozy and warm.

How do I get cheap first-class/business deals to Florence County?
There are ways of booking first or business-class airfares to Florence County that won't burn through your budget. Pick up a seat at the front of the plane for less with these useful tips:

  • Be flexible with your travel dates and wait for huge sales on business or first-class airfares.
  • Budget airlines offer business-class seating at a fraction of the usual price. Ditch the full-service carriers and fly with one these cheaper options.
  • Make a bid for an upgrade. Some carriers hold online auctions that let you offer a price for a seat at the front of the plane. You may also be able to upgrade with points earned through a loyalty program.

What is the best time to go to Florence County?
If you'd like to experience Florence County in the peak season, March, April and July are the top months to visit. June 20 marks the onset of summer in the Northern Hemisphere and is an awesome time to travel if you love being outside. During this time of the year, average daily temperatures generally range from 70 ºF to 90 ºF.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.