$66 Cheap flights to Florence County

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Top places to visit in Florence County

Florence. Italy. Panorama of Florence on a sunny day.
FlightsFlights
FlightsFlights

Florence

Florence
a stunning aerial panoramic shot of the blue waters of Lake Hartwell surrounded by vast miles of lush green trees and grass with powerful clouds at sunset in Fair Play South Carolina USA
FlightsFlights
FlightsFlights

Lake City

Lake City

Cheap flights to Florence County from $66 One Way, $132 Round Trip

$132 return flights and $66 one-way flights to Florence County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 20 - Wed, Aug 26
FLL
Fort Lauderdale
MYR
Myrtle Beach
$132 Roundtrip, found 17 hours ago
$132
Roundtrip
found 17 hours ago
Select Breeze Airways flight, departing Thu, Aug 20 from Fort Lauderdale to Myrtle Beach, returning Wed, Aug 26, priced at $132 found 17 hours ago
Sat, Sep 5 - Wed, Sep 9
EWR
New York
MYR
Myrtle Beach
$238 Roundtrip, found 4 days ago
$238
Roundtrip
found 4 days ago
Select United flight, departing Sat, Sep 5 from New York to Myrtle Beach, returning Wed, Sep 9, priced at $238 found 4 days ago
Wed, Sep 23 - Wed, Sep 30
ATL
Atlanta
MYR
Myrtle Beach
$240 Roundtrip, found 3 hours ago
$240
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Wed, Sep 23 from Atlanta to Myrtle Beach, returning Wed, Sep 30, priced at $240 found 3 hours ago
Tue, Nov 17 - Sat, Nov 21
SYR
Syracuse
MYR
Myrtle Beach
$285 Roundtrip, found 11 hours ago
$285
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, Nov 17 from Syracuse to Myrtle Beach, returning Sat, Nov 21, priced at $285 found 11 hours ago
Wed, Aug 12 - Thu, Aug 20
LAX
Los Angeles
MYR
Myrtle Beach
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Wed, Aug 12 from Los Angeles to Myrtle Beach, returning Thu, Aug 20, priced at $290 found 6 days ago
Fri, Aug 14 - Tue, Aug 18
DAL
Dallas
MYR
Myrtle Beach
$320 Roundtrip, found 1 hour ago
$320
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Fri, Aug 14 from Dallas to Myrtle Beach, returning Tue, Aug 18, priced at $320 found 1 hour ago

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
TPAMyrtle BeachJune 20 to June 26$192
FLLMyrtle BeachJune 20 to June 24$270
EWRMyrtle BeachJune 20 to June 25$468
EWRMyrtle BeachJune 20 to June 25$468
DALMyrtle BeachJune 21 to June 25$556
LGAMyrtle BeachJune 21 to June 23$585
BOSMyrtle BeachJune 21 to June 28$662
ALBMyrtle BeachJune 19 to June 26$679
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Florence County Accommodation Deals

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Jun 21 to Jun 22
$100 total
Jun 21 - Jun 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,330 reviews)
"The room was very clean looked like it had been recently renovated"

Reviewed on Jun 16, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Jun 17 to Jun 18
$99 total
Jun 17 - Jun 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Opens in a new windowQuality Inn & Suites Florence Civic Center
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Jun 17 to Jun 18
$76 total
Jun 17 - Jun 18
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,680 reviews)
"We stayed at this hotel last year, and so I felt good about coming back here again because we had such a good experience. My room this time. Definitely was missing a lot of the details when it comes to Cleaning. There is urine behind the toilet seat, led, hair, and the towels, and lots of dust along ..."

Reviewed on Jun 16, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Jun 28 to Jun 29
$95 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (162 reviews)
"Was nice"

Reviewed on Jun 16, 2026

Opens in a new windowSpark by Hilton Florence North I-95, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Florence County

Start your search for cheap flights to Florence County on Orbitz. Orbitz is where you will discover guaranteed low prices on Florence County flights, as well as all of the following conveniences:

Travel Updates on Your Mobile Device

Orbitz offers cutting-edge mobile tools for your smartphone. Whether you own an iPhone or an Android phone, you can benefit from Orbitz’s flight status updates and even book your future Florence County flights. You can also review and reserve hotel rooms for when your Florence County flights land and see other special offers.

Low Prices Guaranteed on Flights to Florence County

Orbitz offers large discounts on a wide range of Florence County flights. Through our easy-to-use site, you can find, plan, and reserve your desired flights to Florence County while taking advantage of the lowest fares around.

Customer Care When You Need It

Orbitz is dedicated to making your flight booking experience as stress-free as possible. If you need to cancel your reservation, you can do so at your own convenience by going to the Orbitz website. If you need to change your flights to Florence County to another time or date, you can contact our customer service representatives by phone, and they help you make the flight adjustments you need.

Loyalty Program Participation Opportunities

Orbitz lets you add your loyalty or frequent flyer account numbers when you book qualifying flights to Florence County. So don’t worry about missing out on earning miles or points simply because you aren’t booking with the airline directly. You can save on your flights, and rack up miles too.

Frequently asked questions

What is the best airport to fly to in Florence County?
There's one main entry point for this region — Florence Regional Airport (FLO). Book your flights to this popular gateway and see all that Florence County has to offer.
How much is a flight to Florence County?
Round-trip prices dropped as low as $132 this week to Florence County, and reached a high of $679. Passengers flying out of Fort Lauderdale (FLL) managed to land one-way flights from just $66.
How to book the cheapest flight to Florence County?
Snapping up cheap flights to Florence County is as simple as booking your ticket with Orbitz. But if you'd love to make sure you're nabbing the best flight deals around, here are a few tips worth following:

  • Depending on your place of departure, choose the 'Nearby airports' function (located under the departure and arrival options). At times, other departure points will have cheaper fares.
  • Also, click on the 'Show flexible dates' link to view the prices for days around your chosen departure. You may be able to pick up cheaper flight deals if you're flexible with your schedule.
  • You can also use the 'Show options' link to filter results for your preferred carrier, seating class, nonstop flights and refundable flights. Under 'Sort & Filter' to the left, you can even choose the time of day you want to fly.
  • Once you've sorted out your travel dates, don't delay booking. Prices generally increase as the departure date nears.
  • Think about bundling your hotels, flights and car rental into an Orbitz package — the more you book, the more you save.
  • Flying during busier seasons means steep airfares. If possible, plan your trip outside of popular periods, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Florence County?
Generally speaking, January is the cheapest time to purchase your plane ticket. This is closely followed by February and August. Bear this in mind while you search for a cheap flight to Florence County.
What day of the week is the cheapest to book a flight to Florence County?
If you're after inexpensive fares to Florence County, the best days to make a booking are Tuesdays, Wednesdays and Saturdays. With Orbitz (and some good timing!), an unbeatable flight deal will be all yours.
What is the cheapest day of the week to fly to Florence County?
Based on Orbitz data from 2020, Monday tends to be the best day to nab cheap flights to Florence County. Tuesday also offers budget-friendly airfares, whereas Saturday has the most expensive ticket prices. Although flying out at the weekend can be more suitable, you'll have more money in your pocket to play with if you jet out early in the week.
What is the cheapest month to fly to Florence County?
If you're flexible with your travel dates, consider leaving during August. Orbitz data shows that this is generally the best month to take off if you're looking for cheap flights to Florence County. As you would imagine, fares get pricier in June and flights book out quickly.
Which airlines allow free cancellation?
Life changes, and we believe your ticket should be able to do the same. That's why Orbitz makes it a snap to search for airlines with free cancellation and no change fees. Just enter your departure and arrival points and then select "Filter by flexible change policies." How's that for peace of mind?
What do I need for the flight to Florence County?
Whether you're accustomed to flying or you're new to the skies, it's always great to be prepared when you travel. Here are several tips and things to take into consideration:

  • Make sure you've packed your travel documents and identification. For overseas trips, you'll need your passport. When booking your seats, always use the same name, birth date and gender as listed on your current ID.
  • Pack your carry-on bag with snacks and things to keep you busy and watch time whiz by on this medium-haul flight. Wherever possible, hop on the airport's Wi-Fi and transfer your favorite playlist or podcast to your phone or tablet before take off.
  • Never mind what the season is, airplane cabins are often quite cold. Bring a sweater with you on your journey to stay cozy and warm.

How do I get cheap first-class/business deals to Florence County?
There are ways of booking first or business-class airfares to Florence County that won't burn through your budget. Pick up a seat at the front of the plane for less with these useful tips:

  • Be flexible with your travel dates and wait for huge sales on business or first-class airfares.
  • Budget airlines offer business-class seating at a fraction of the usual price. Ditch the full-service carriers and fly with one these cheaper options.
  • Make a bid for an upgrade. Some carriers hold online auctions that let you offer a price for a seat at the front of the plane. You may also be able to upgrade with points earned through a loyalty program.

What is the best time to go to Florence County?
If you'd like to experience Florence County in the peak season, March, April and July are the top months to visit. June 20 marks the onset of summer in the Northern Hemisphere and is an awesome time to travel if you love being outside. During this time of the year, average daily temperatures generally range from 70 ºF to 90 ºF.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.