DeSoto County Vacation Rentals

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Top cities in DeSoto County

a stunning panoramic shot of the Memphis-Arkansas Bridge over the vast flowing waters of the Mississippi river with blue sky and powerful yellow clouds and dry brush on the banks of the river
Vacation RentalsVacation Rentals
Vacation RentalsVacation Rentals

Horn Lake

Horn Lake

DeSoto County Vacation Rentals

Spacious 5-bedroom house with WiFi, AC and parking in peaceful Southaven.

Spacious 5-bedroom house with WiFi, AC and parking in peaceful Southaven.

Southaven MS
At this vacation home, guests have access to features like laundry facilities.
Kitchen
Washer
Private Pool Oasis + Luxury Cabana Entertainment

Private Pool Oasis + Luxury Cabana Entertainment

Horn Lake MS
At this vacation home, guests have access to a gym, laundry facilities, and barbecue grills. This smoke-free vacation home also has a garden.
The Quiet Place-Charming 3-bedroom house; 2 Minutes from Olive Branch, MS

The Quiet Place-Charming 3-bedroom house; 2 Minutes from Olive Branch, MS

Memphis TN
$139 nightly
The price is $155 total per night
$155 total
Jun 23 - Jun 24
Total with taxes and fees
This vacation home features a hot tub and laundry facilities.
1 Queen Bed | Non-Smoking, Kitchen

1 Queen Bed | Non-Smoking, Kitchen

Memphis TN
Free Cancellation
$68 nightly
The price is $84 total per night
$84 total
Jun 25 - Jun 26
Total with taxes and fees
This apartment is a smoke-free apartment building.
Hot Tub+Gas Fire Pit+Outdoor Oasis+Lights+Murals

Hot Tub+Gas Fire Pit+Outdoor Oasis+Lights+Murals

Memphis TN
Guests staying at this vacation home enjoy a hot tub and laundry facilities.
Come visit the stunning home in Midtown Memphis

Come visit the stunning home in Midtown Memphis

Memphis TN
$248 nightly
The price is $291 total per night
$291 total
Jun 29 - Jun 30
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Cool cozy vacation home in Glenview 10 minutes from Tiger Stadium

Cool cozy vacation home in Glenview 10 minutes from Tiger Stadium

Memphis TN
$224 nightly
The price is $264 total per night
$264 total
Jun 23 - Jun 24
Total with taxes and fees
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.
4 Bedroom Memphis Historic Home and Summer In-ground Swimming Pool

4 Bedroom Memphis Historic Home and Summer In-ground Swimming Pool

Memphis TN
At this vacation home, guests have access to an outdoor pool, laundry facilities, and barbecue grills.
The Stallion

The Stallion

4.5 out of 5
436 S Front St Memphis TN
Free Cancellation
Reserve now, pay when you stay
$185 nightly
The price is $219 total per night
$219 total
Jun 21 - Jun 22
Total with taxes and fees
At The Stallion, guests have access to free WiFi in public areas and laundry facilities. Free parking is included with your stay. Staff members can help with accommodation requests, and provide luggage storage.
Downtown Memphis Loft Apartment

Downtown Memphis Loft Apartment

Memphis TN
$120 nightly
The price is $141 total per night
$141 total
Jun 23 - Jun 24
Total with taxes and fees
This apartment features a gym and laundry facilities.
2BR 2.5 BA Memphis Condo - Prime Downtown Location!

2BR 2.5 BA Memphis Condo - Prime Downtown Location!

Memphis TN
$287 nightly
The price is $337 total per night
$337 total
Jun 21 - Jun 22
Total with taxes and fees
At this condo, guests have access to features like laundry facilities. This smoke-free condo building also has barbecue grills.
The Moose

The Moose

4 out of 5
669 Adams Ave Memphis TN
Free Cancellation
Reserve now, pay when you stay
$135 nightly
The price is $161 total per night
$161 total
Jul 7 - Jul 8
Total with taxes and fees
Guests of The Moose enjoy free WiFi in public areas, express check-in, and express check-out. Free parking is available if you drive. Additional amenities include laundry facilities, barbecue grills, and a water dispenser.
Cozy Highrise 2 br Apt - Downtown Memphis!

Cozy Highrise 2 br Apt - Downtown Memphis!

Memphis TN
$130 nightly
The price is $153 total per night
$153 total
Jun 21 - Jun 22
Total with taxes and fees
This apartment features a gym and laundry facilities. If you drive, take advantage of free offsite parking.
Your Home away from Home in Memphis, Tn. Minutes from all Memphis attractions

Your Home away from Home in Memphis, Tn. Minutes from all Memphis attractions

Memphis TN
Guests staying at this cottage have access to laundry facilities, barbecue grills, and a garden.
Landing Furnished Apartments Harborside - Memphis

Landing Furnished Apartments Harborside - Memphis

4 out of 5
645 N Front St Memphis TN
Landing Furnished Apartments Harborside - Memphis offers a gym, a rooftop terrace, and free WiFi in public areas. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area and pet grooming services. Additional amenities include a seasonal outdoor pool and barbecue grills.
Midtown Retreat - 4mi to Downtown / Large Private Deck

Midtown Retreat - 4mi to Downtown / Large Private Deck

Memphis TN
$274 nightly
The price is $321 total per night
$321 total
Jul 13 - Jul 14
Total with taxes and fees
At this vacation home, guests have access to an arcade/game room, laundry facilities, and barbecue grills.
Uptown Modern Escape - 4bd/2ba

Uptown Modern Escape - 4bd/2ba

Memphis TN
$239 nightly
The price is $281 total per night
$281 total
Jun 21 - Jun 22
Total with taxes and fees
This vacation home is a smoke-free vacation home.
stayAPT Suites Memphis-Cordova-Wolfchase

stayAPT Suites Memphis-Cordova-Wolfchase

4 out of 5
1667 Chickering Ln Cordova TN
Guests of stayAPT Suites Memphis-Cordova-Wolfchase enjoy features like a gym, free WiFi in public areas, and laundry facilities. If you drive, put free parking to good use. Additional amenities include a vending machine and barbecue grills.
Don't see what you're looking for?
See all available properties in DeSoto County
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in DeSoto County

    Drury Inn & Suites Memphis Southaven

    Drury Inn & Suites Memphis Southaven

    735 Goodman Rd W. Horn Lake MS
    $100 nightly
    The price is $111 total per night from Jul 19 to Jul 20
    $111 total
    Jul 19 - Jul 20
    Total with taxes and fees
    9.4/10 Exceptional! (1,020 reviews)
    Hometown Place Olive Branch

    Hometown Place Olive Branch

    11064 Business Center Dr Olive Branch MS
    $75 nightly
    The price is $82 total per night from Jun 21 to Jun 22
    $82 total
    Jun 21 - Jun 22
    Total with taxes and fees
    8/10 Very Good! (256 reviews)
    Historic Whispering Woods Hotel & Conference Center

    Historic Whispering Woods Hotel & Conference Center

    7300 Hacks Cross Rd Olive Branch MS
    $109 nightly
    The price is $120 total per night from Jun 19 to Jun 20
    $120 total
    Jun 19 - Jun 20
    Total with taxes and fees
    7.4/10 Good! (1,012 reviews)

Orbitz makes it easy to find vacation rentals in DeSoto County 

🏠 What is the best price for a DeSoto County vacation rental?


DeSoto County rentals range between $82 and $337 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in DeSoto County can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next DeSoto County getaway. Orbitz filters your search results so you can find the best DeSoto County vacation rental for you. We have tons of options.


🏠 Are cancellations free on DeSoto County vacation rentals with Orbitz?


You may be able to cancel or amend your DeSoto County vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in DeSoto County?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in DeSoto County by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My TripsOpens in a new window on your Orbitz account page to find the right information contact. If you need more help, visit our Customer ServiceOpens in a new window page. 


🏠 What are the advantages of booking a vacation rental in DeSoto County?


When you book a DeSoto County vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in DeSoto County?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across DeSoto County—with plenty of hidden gems. We also have plenty of inventory in DeSoto County main cities and near popular attraction spots.


🏠 Why should I book my DeSoto County vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream DeSoto County vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


More to Explore