Book 5 Star Hotels in Southeastern Indiana
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Featured Southeastern Indiana 5 Stars Hotels
Radisson Hotel Louisville North
505 Marriott Drive Clarksville IN
Free Cancellation
Reserve now, pay when you stay
19.58 mi from city center
$51 nightly
The price is $58 total per night
$58 total
Dec 8 - Dec 9
Total with taxes and fees
Guests of Radisson Hotel Louisville North enjoy an indoor pool, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The 24-hour front desk has multilingual staff ready to assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and a seasonal outdoor pool.
Hilton Garden Inn Jeffersonville Louisville North
4900 Water Tower Road Jeffersonville IN
Free Cancellation
Reserve now, pay when you stay
18 mi from city center
$83 nightly
The price is $94 total per night
$94 total
Dec 6 - Dec 7
Total with taxes and fees
Hilton Garden Inn Jeffersonville Louisville North features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. Free parking is included with your stay. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include a reception hall and a convenience store.
Pet friendly
Parking included
Comfort Inn & Suites Clarksville - Louisville North
1485 Broadway St Clarksville IN
Free Cancellation
Reserve now, pay when you stay
17.46 mi from city center
$94 nightly
The price is $107 total per night
$107 total
Dec 27 - Dec 28
Total with taxes and fees
Guests of Comfort Inn & Suites Clarksville - Louisville North have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, laundry facilities, and a banquet hall.
Pool
Breakfast included
Sheraton Louisville Riverside by Marriott
700 West Riverside Drive Jeffersonville IN
Free Cancellation
Reserve now, pay when you stay
20.68 mi from city center
$80 nightly
The price is $90 total per night
$90 total
Dec 22 - Dec 23
Total with taxes and fees
Guests staying at Sheraton Louisville Riverside by Marriott enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking and a free area shuttle. Multilingual staff at the front desk are standing by 24/7 to help with dry cleaning/laundry, tours or tickets, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Pet friendly
Hampton Inn New Albany Louisville West
411 W Spring Street New Albany IN
Free Cancellation
Reserve now, pay when you stay
17.67 mi from city center
$83 nightly
The price is $94 total per night
$94 total
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn New Albany Louisville West features a gym, free WiFi in public areas, and a conference center. Free parking is available if you drive. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included
TownePlace Suites by Marriott Louisville North
301 West Maple Street Jeffersonville IN
20.63 mi from city center
$101 nightly
The price is $114 total per night
$114 total
Dec 21 - Dec 22
Total with taxes and fees
Guests staying at TownePlace Suites by Marriott Louisville North enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables, dry cleaning/laundry, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a computer station.
Ramada by Wyndham Sellersburg/Louisville North
360 Triangle Dr Sellersburg IN
Free Cancellation
Reserve now, pay when you stay
13.75 mi from city center
$72 nightly
The price is $82 total per night
$82 total
Dec 7 - Dec 8
Total with taxes and fees
At Ramada by Wyndham Sellersburg/Louisville North, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include laundry facilities, a banquet hall, and a gift shop.
Home2 Suites by Hilton Clarksville Louisville North
1624 Leisure Way Clarksville IN
Free Cancellation
Reserve now, pay when you stay
17.26 mi from city center
$114 nightly
The price is $128 total per night
$128 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
At Home2 Suites by Hilton Clarksville Louisville North, guests have access to a 24-hour gym, free WiFi in public areas, and a business center. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help with securing valuables and dry cleaning/laundry. Additional amenities include coffee/tea in a common area, a terrace, and laundry facilities.
Breakfast included
Pet friendly
Hampton Inn Louisville-North/Clarksville
1501 Broadway Clarksville IN
Free Cancellation
Reserve now, pay when you stay
17.4 mi from city center
$84 nightly
The price is $95 total per night
$95 total
Dec 9 - Dec 10
Total with taxes and fees
At Hampton Inn Louisville-North/Clarksville, guests have access to a gym, free WiFi in public areas, and meeting rooms. You can put free parking to good use if you drive. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, concierge services, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best 5 star hotels in Southeastern Indiana
Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Southeastern Indiana. After all, treating yourself to the finer things is what vacations are about.
What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Southeastern Indiana hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.
What amenities can I expect at a 5 star hotel?
Southeastern Indiana 5 star hotels and resorts typically offer luxury amenities such as:
- Gourmet restaurant
- Full-service fitness center with pool
- Luxury spa
- Welcome gifts upon arrival
- Top-of-the-line beds and linens
- Designer personal care products
- Premium cable, free Wi-Fi and device docking stations
How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Southeastern Indiana with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place:
- Search hotels by price, ranging from $58 to $128
- Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
- Choose from 1,134 5 star hotels in Southeastern Indiana!
Southeastern Indiana hotels essential information
Accommodation | 1,134 hotels |
|---|---|
Lowest Price | $58 |
Highest Price | $128 |
Popular hotels | Radisson Hotel Louisville North, Hilton Garden Inn Jeffersonville Louisville North, Comfort Inn & Suites Clarksville - Louisville North, Sheraton Louisville Riverside by Marriott, Hampton Inn New Albany Louisville West, TownePlace Suites by Marriott Louisville North, Ramada by Wyndham Sellersburg/Louisville North, Home2 Suites by Hilton Clarksville Louisville North, Hampton Inn Louisville-North/Clarksville |
Recent Reviews
Radisson Hotel Louisville North
5/5 Excellent
"Clean room, great staff.
We enjoyed our stay."
A verified traveler stayed at Radisson Hotel Louisville North
Posted 3 days ago
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