Book 2 Star Hotels in Seneca
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Seneca 2 Stars Hotels

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Free Cancellation
Reserve now, pay when you stay
5.27 mi from city center
$123 nightly
The price is $135 total per night
$135 total
Dec 27 - Dec 28
Total with taxes and fees
Guests staying at Lakeside Lodge Clemson enjoy a 24-hour gym, free WiFi in public areas, and a hot tub. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with securing valuables and concierge services. Additional amenities include a seasonal outdoor pool and a banquet hall.
Pool
Hot Tub

Tru by Hilton Seneca Clemson
13050 Clemson Blvd Seneca SC
Free Cancellation
Reserve now, pay when you stay
5.12 mi from city center
$100 nightly
The price is $110 total per night
$110 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Tru by Hilton Seneca Clemson features a gym, free WiFi in public areas, and a business center. You can take advantage of free parking if you drive. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include coffee/tea in a common area, an arcade/game room, and laundry facilities.
Breakfast included
Pet friendly

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Free Cancellation
Reserve now, pay when you stay
0.16 mi from city center
$79 nightly
The price is $87 total per night
$87 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Quality Inn Seneca Clemson Area US-123 enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. Free parking is available if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include coffee/tea in a common area, a water dispenser, and a vending machine.
Pool
Breakfast included

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
Free Cancellation
Reserve now, pay when you stay
1.15 mi from city center
$119 nightly
The price is $131 total per night
$131 total
Dec 28 - Dec 29
Total with taxes and fees
Hampton Inn & Suites Seneca-Clemson Area features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
Free Cancellation
Reserve now, pay when you stay
1.92 mi from city center
$73 nightly
The price is $80 total per night
$80 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Days Inn by Wyndham Seneca / Clemson Area enjoy access to free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. A stay here includes free parking. The 24-hour front desk has staff always at the ready. Additional amenities include free newspapers, laundry facilities, and a vending machine.
Pool
Breakfast included

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
4.92 mi from city center
$129 nightly
The price is $142 total per night
$142 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
If you drive, take advantage of free parking. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls.
Kitchen
Pet friendly

Best Western Seneca-Clemson
511 Bypass Highway 123 Seneca SC
Free Cancellation
Reserve now, pay when you stay
0.81 mi from city center
$93 nightly
The price is $102 total per night
$102 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Best Western Seneca-Clemson enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Additional amenities include a computer station, free newspapers, and a vending machine.
Pool
Breakfast included

Fairfield Inn & Suites Seneca Clemson Univ Area
800 BYPASS 123 Seneca SC
Free Cancellation
Reserve now, pay when you stay
1.08 mi from city center
$115 nightly
The price is $127 total per night
$127 total
Dec 30 - Dec 31
Total with taxes and fees
At Fairfield Inn & Suites Seneca Clemson Univ Area , guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Seneca hotels essential information
Accommodation | 1,655 hotels |
|---|---|
Lowest Price | $80 |
Highest Price | $142 |
Popular hotels | Lakeside Lodge Clemson, Tru by Hilton Seneca Clemson, Quality Inn Seneca Clemson Area US-123, Hampton Inn & Suites Seneca-Clemson Area, Days Inn by Wyndham Seneca / Clemson Area, Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy, Best Western Seneca-Clemson, Fairfield Inn & Suites Seneca Clemson Univ Area , Fabulous Tiny House with AC in charming Seneca |
Recent Reviews

Tru by Hilton Seneca Clemson
5/5 Excellent
"Staff is amazing, hotel and amenities are great. "
A verified traveler stayed at Tru by Hilton Seneca Clemson
Posted 2 days ago



