Cheap flights from DSM to LAF (Des Moines Intl. to Purdue University)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Hotel Ideas near Purdue University

Airport Hotels near Purdue University

The Union Club Hotel at Purdue University, Autograph Collection

The Union Club Hotel at Purdue University, Autograph Collection

3.5 out of 5
201 Grant Street West Lafayette IN
$233 nightly
The price is $261 total per night from Dec 28 to Dec 29
$261 total
Dec 28 - Dec 29
Total with taxes and fees
Book a stay at this spa hotel in West Lafayette. Enjoy a full-service spa, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.6/10 Exceptional! (487 reviews)
Yes!

Reviewed on Dec 7, 2025

The Union Club Hotel at Purdue University, Autograph Collection
Hilton Garden Inn West Lafayette Wabash Landing

Hilton Garden Inn West Lafayette Wabash Landing

3 out of 5
356 E State St West Lafayette IN
$103 nightly
The price is $116 total per night from Dec 22 to Dec 23
$116 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (238 reviews)
Yes

Reviewed on Nov 27, 2025

Hilton Garden Inn West Lafayette Wabash Landing
Hampton Inn & Suites West Lafayette

Hampton Inn & Suites West Lafayette

2.5 out of 5
160 Tapawingo Drive West Lafayette IN
$103 nightly
The price is $116 total per night from Dec 22 to Dec 23
$116 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
d

Reviewed on Dec 4, 2025

Hampton Inn & Suites West Lafayette
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Lafayette

Hilton Garden Inn West Lafayette Wabash Landing

Hilton Garden Inn West Lafayette Wabash Landing

3 out of 5
356 E State St West Lafayette IN
$103 nightly
The price is $116 total per night from Dec 22 to Dec 23
$116 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (238 reviews)
Yes

Reviewed on Nov 27, 2025

Hilton Garden Inn West Lafayette Wabash Landing
The Union Club Hotel at Purdue University, Autograph Collection

The Union Club Hotel at Purdue University, Autograph Collection

3.5 out of 5
201 Grant Street West Lafayette IN
$233 nightly
The price is $261 total per night from Dec 28 to Dec 29
$261 total
Dec 28 - Dec 29
Total with taxes and fees
Book a stay at this spa hotel in West Lafayette. Enjoy a full-service spa, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.6/10 Exceptional! (487 reviews)
Yes!

Reviewed on Dec 7, 2025

The Union Club Hotel at Purdue University, Autograph Collection
Quality Inn West Lafayette - University Area

Quality Inn West Lafayette - University Area

2.5 out of 5
1600 Cumberland Ave West Lafayette IN
$72 nightly
The price is $81 total per night from Dec 16 to Dec 17
$81 total
Dec 16 - Dec 17
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
5.8/10 (1,004 reviews)
great value for money!

Reviewed on Dec 7, 2025

Quality Inn West Lafayette - University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Lafayette Hotels

Campus Inn

Campus Inn

2 out of 5
200 Brown Street West Lafayette IN
Stay at this motel in West Lafayette. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Wabash Heritage Trail and Purdue Bell Tower ...
Good value for overnight stay
An older motel but kept clean. Staff was pleasant.

Reviewed on Oct 16, 2021

Campus Inn
Prestige Inn West Lafayette

Prestige Inn West Lafayette

2 out of 5
1217 Sagamore Pkwy West West Lafayette IN
$68 nightly
The price is $76 total per night from Dec 15 to Dec 16
$76 total
Dec 15 - Dec 16
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (819 reviews)
good value place to stay if you're visiting the campus

Reviewed on Nov 30, 2025

Prestige Inn West Lafayette
Quality Inn West Lafayette - University Area

Quality Inn West Lafayette - University Area

2.5 out of 5
1600 Cumberland Ave West Lafayette IN
$72 nightly
The price is $81 total per night from Dec 16 to Dec 17
$81 total
Dec 16 - Dec 17
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
5.8/10 (1,004 reviews)
great value for money!

Reviewed on Dec 7, 2025

Quality Inn West Lafayette - University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Lafayette

Quality Inn West Lafayette - University Area

Quality Inn West Lafayette - University Area

2.5 out of 5
1600 Cumberland Ave West Lafayette IN
$72 nightly
The price is $81 total per night from Dec 16 to Dec 17
$81 total
Dec 16 - Dec 17
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
5.8/10 (1,004 reviews)
great value for money!

Reviewed on Dec 7, 2025

Quality Inn West Lafayette - University Area
Hampton Inn & Suites West Lafayette

Hampton Inn & Suites West Lafayette

2.5 out of 5
160 Tapawingo Drive West Lafayette IN
$103 nightly
The price is $116 total per night from Dec 22 to Dec 23
$116 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
d

Reviewed on Dec 4, 2025

Hampton Inn & Suites West Lafayette
Hilton Garden Inn West Lafayette Wabash Landing

Hilton Garden Inn West Lafayette Wabash Landing

3 out of 5
356 E State St West Lafayette IN
$103 nightly
The price is $116 total per night from Dec 22 to Dec 23
$116 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Lafayette. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (238 reviews)
Yes

Reviewed on Nov 27, 2025

Hilton Garden Inn West Lafayette Wabash Landing
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DSM to LAF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What airlines have the most flights from Des Moines Intl. Airport (DSM) to LAF?
Do some people-watching, have a coffee, stretch your legs … Airport stopovers don't have to be dull! If you're planning to travel from Des Moines Intl. Airport to LAF, you won't find any direct flights. Get ready for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore