Cheap flights from BUF to SAN (Buffalo Niagara Intl. to San Diego Intl.)

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Cheap Flights from BUF to SAN starting at $175 One Way, $344 Round Trip

Prices starting at $344 for return flights and $175 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Aug 12 - Sun, Aug 16
BUF
Buffalo
SAN
San Diego
$344 Roundtrip, found 2 days ago
$344
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, Aug 12 from Buffalo to San Diego, returning Sun, Aug 16, priced at $344 found 2 days ago
Thu, Dec 24 - Sun, Jan 3
BUF
Buffalo
SAN
San Diego
$349 Roundtrip, found 15 hours ago
$349
Roundtrip
found 15 hours ago
Select Delta flight, departing Thu, Dec 24 from Buffalo to San Diego, returning Sun, Jan 3, priced at $349 found 15 hours ago
Wed, Aug 12 - Sun, Aug 16
BUF
Buffalo
SAN
San Diego
$350 Roundtrip, found 2 days ago
$350
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, Aug 12 from Buffalo to San Diego, returning Sun, Aug 16, priced at $350 found 2 days ago
Thu, Dec 24 - Sun, Jan 3
BUF
Buffalo
SAN
San Diego
$354 Roundtrip, found 15 hours ago
$354
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Dec 24 from Buffalo to San Diego, returning Sun, Jan 3, priced at $354 found 15 hours ago
Fri, Aug 7 - Tue, Aug 11
BUF
Buffalo
SAN
San Diego
$354 Roundtrip, found 2 days ago
$354
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Fri, Aug 7 from Buffalo to San Diego, returning Tue, Aug 11, priced at $354 found 2 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from May 25 to May 26
$194 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,531 reviews)
Really bad, dissapointing.

Reviewed on May 8, 2026

Sheraton San Diego Resort
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$161 nightly
The price is $186 total per night from May 11 to May 12
$186 total
May 11 - May 12
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,041 reviews)
When I arrived at the hotel the First Lady was very nice. Went into my room tv not working. Called and inform within 10 mins of checking in. During a 3 hour waiting period we called an additional 2x for the tv to be fixed. Asked for face towels (hand wash cloths) whichever term you prefer. They brought ...

Reviewed on May 10, 2026

The Sofia Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$174 nightly
The price is $201 total per night from May 25 to May 26
$201 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,193 reviews)
The bed had stains on it. We checked in around 10/11 am. They said they would text us when the room was ready. That never happened. Instead we went back to the hotel and had to wait in an hour line to be told they didn’t have a room for us at all. The lady had to contact her manager to see if they ...

Reviewed on May 10, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
The price is $186 total per night from May 11 to May 12
$186 total
per night
May 11 - May 12
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,040 reviews)
Great location.

Reviewed on May 10, 2026

The Sofia Hotel
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
The price is $305 total per night from May 25 to May 26
$305 total
per night
May 25 - May 26
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,850 reviews)
Great location and clean hotel.

Reviewed on May 9, 2026

Manchester Grand Hyatt San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is $235 total per night from May 11 to May 12
$235 total
per night
May 11 - May 12
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,654 reviews)
Great experience overall- everything met expectations

Reviewed on May 9, 2026

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$174 nightly
The price is $201 total per night from May 25 to May 26
$201 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,193 reviews)
The bed had stains on it. We checked in around 10/11 am. They said they would text us when the room was ready. That never happened. Instead we went back to the hotel and had to wait in an hour line to be told they didn’t have a room for us at all. The lady had to contact her manager to see if they ...

Reviewed on May 10, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from May 25 to May 26
$194 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,531 reviews)
Really bad, dissapointing.

Reviewed on May 8, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$141 nightly
The price is $162 total per night from May 13 to May 14
$162 total
May 13 - May 14
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,068 reviews)
I enjoyed the pool and was pleasantly surprised by both the comfortable temp and the quiet/all to myself experience 😁

Reviewed on May 9, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$110 nightly
The price is $126 total per night from May 11 to May 12
$126 total
May 11 - May 12
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,394 reviews)
Conveniently located off freeway. Amazing staff clean rooms definitely stay again

Reviewed on May 9, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$62 nightly
The price is $71 total per night from May 11 to May 12
$71 total
May 11 - May 12
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,134 reviews)
It’s not cleaning

Reviewed on May 9, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$102 nightly
The price is $118 total per night from May 11 to May 12
$118 total
May 11 - May 12
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,711 reviews)
It’s 5 starts for the price. There are premium hotels around it for double the cost. Rooms were clean. The bed was very comfortable. The bathroom has everything you need and was clean. I didn’t use the pool but it’s big and looked good. SD weather didn’t allow it. Breakfast wasn’t included but there’s ...

Reviewed on May 10, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$223 nightly
The price is $257 total per night from May 17 to May 18
$257 total
May 17 - May 18
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (2,064 reviews)
We stayed 5 days. The staff was amazing. The beaches were cleaned daily. For the big events, they had security atthe entrance to keep out event patrons so the hotel patrons had plenty of parking. We rented bikes to go ride on the boardwalk, which was 2 blocks up from hotel, then we were able to keep ...

Reviewed on May 10, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$224 nightly
The price is $257 total per night from May 11 to May 12
$257 total
May 11 - May 12
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,351 reviews)
We had a great stay at The Dana. The property is beautiful and my kid loved riding her tricycle along the boardwalk. The pools were nicely heated, warm but not gross warm. The pools next to the restaurant has an 2.5 foot depth at one end so my little ones could stand and swim around. Great time.

Reviewed on May 10, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$295 nightly
The price is $339 total per night from May 11 to May 12
$339 total
May 11 - May 12
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,246 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
Best place ever

Reviewed on May 10, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

BUF to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
While you can't fly directly from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN), there are several air carriers that operate on this route with only one stopover. Why not find out if the dates and times available with Southwest Airlines or Delta Air Lines complement your travel plans? If they don't, there's always American Airlines.
What is the shortest flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
From Buffalo, the unique sights and sounds of San Diego are 7 hours and 7 minutes away. Choose your favorite seat, or maybe even one with a little more legroom, and jet to your destination in total comfort.
How many hours flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Airport?
It usually takes about 7 hours and 14 minutes to jet from BUF to SAN. Breeze through the journey by watching TV shows and reading magazines. Alternatively, squeeze in a bit of shut-eye.
What airlines have the most flights from Buffalo Niagara International Airport to SAN?
Watch the planes take off and land, have a coffee, strike up a conversation with a stranger ... Airport stopovers don't have to be annoying! If you're planning to travel from BUF to SAN, you can't fly direct. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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