$126 Cheap flight deals from Quad Cities (MLI) to Biloxi (MOB)

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This Weekend's Flight Deals from Quad Cities to Biloxi

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 24 - Fri, Oct 31
MLI
Quad City Intl.
MSY
Louis Armstrong New Orleans Intl.
$297 Roundtrip, found 17 hours ago
$297
Roundtrip
found 17 hours ago
Select Delta flight, departing Fri, Oct 24 from Quad City Intl. to Louis Armstrong New Orleans Intl., returning Fri, Oct 31, priced at $297 found 17 hours ago

Airfares from $126 One Way, $253 Round Trip from Quad Cities to Biloxi

Prices starting at $253 for return flights and $126 for one-way flights to Biloxi were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 31 - Fri, Nov 14
MLI
Moline
MSY
New Orleans
$253 Roundtrip, found 5 days ago
$253
Roundtrip
found 5 days ago
Select United flight, departing Fri, Oct 31 from Moline to New Orleans, returning Fri, Nov 14, priced at $253 found 5 days ago
Tue, Dec 9 - Sat, Dec 13
MLI
Moline
MSY
New Orleans
$253 Roundtrip, found 2 days ago
$253
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Dec 9 from Moline to New Orleans, returning Sat, Dec 13, priced at $253 found 2 days ago
Sat, Nov 22 - Fri, Nov 28
MLI
Moline
MSY
New Orleans
$253 Roundtrip, found 9 hours ago
$253
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Nov 22 from Moline to New Orleans, returning Fri, Nov 28, priced at $253 found 9 hours ago
Fri, Oct 31 - Fri, Nov 14
MLI
Moline
MSY
New Orleans
$258 Roundtrip, found 5 days ago
$258
Roundtrip
found 5 days ago
Select United flight, departing Fri, Oct 31 from Moline to New Orleans, returning Fri, Nov 14, priced at $258 found 5 days ago
Thu, Dec 11 - Sat, Dec 13
MLI
Moline
MSY
New Orleans
$278 Roundtrip, found 2 days ago
$278
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Dec 11 from Moline to New Orleans, returning Sat, Dec 13, priced at $278 found 2 days ago

Biloxi economy flight packages

Price found within the past 48 hours. Click for updated prices.
Omni Royal Orleans Hotel
4.0-star property

Omni Royal Orleans Hotel

8.8/10 Excellent! (1,848 reviews)

Nov 19 - Nov 23

4 night stay

Moline (MLI) to New Orleans (MSY)

American Airlines • Non-stop roundtrip • Coach
Price was $935, price is now $773 per person
$773
per person
found 1 day ago
This is the best location for a hotel! It's an easy walk to all the most popular areas including bourbon st, canal st, and royal Street but is far enough away from bourbon street that you can actually get some sleep at night. The staff here is fantastic, they make a point to remember guests and make you feel at home. We came to the hotel to celebrate our wedding and when we told the staff that they went out of their way to make it a special stay for us. Ms Yates was especially kind and made us feel like family. We loved this hotel and when we come back to New Orleans this is the only hotel we would look to stay in.

Reviewed on Sep 3, 2025

French Quarter Lanaux Mansion B & B
3.0-star property

French Quarter Lanaux Mansion B & B

10/10 Exceptional! (6 reviews)

Nov 19 - Nov 23

4 night stay

Moline (MLI) to New Orleans (MSY)

American Airlines • Non-stop roundtrip • Coach
Price was $1,512, price is now $1,190 per person
$1,190
per person
found 1 day ago
Melrose Mansion
4.0-star property

Melrose Mansion

9.2/10 Wonderful! (1,008 reviews)

Nov 19 - Nov 23

4 night stay

Moline (MLI) to New Orleans (MSY)

American Airlines • Non-stop roundtrip • Coach
Price was $954, price is now $779 per person
$779
per person
found 1 day ago
It was a pleasure to stay at Melrose. We had late check in (12 am) and the security was very accommodating. Everyone at this property was so welcoming and offered to bring whatever we needed to our suite. Bonus: everything is within walking distance (10-15 min walk). Ubers and Lyfts are always nearby if you’re feeling lazy. I will certainly be back!

Reviewed on Mar 16, 2025

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More About Flying To Biloxi from Quad Cities

Route Information for Flights from Quad Cities to Biloxi

Origin Airport IATA Code
MLI
Destination Airport IATA Code
MOB
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Quad Cities to Biloxi

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Frequently asked questions

What is the shortest flight from Quad Cities to Biloxi?
The quickest flight from Moline, IL (MLI-Quad City Intl.) to New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) is 3 hours and 22 minutes. Slip a few things into your carry-on to keep you entertained, like a gripping read or a crossword puzzle.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.