Cheap flights from CPT to TMS (Cape Town Intl. to São Tomé Intl.)

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Cheap Flights from CPT to TMS starting at $461 One Way, $2,317 Round Trip

Prices starting at $2,317 for return flights and $461 for one-way flights to São Tomé Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jan 11 - Sun, Jan 18
CPT
Cape Town
TMS
São Tomé Island
$2,317 Roundtrip, found 3 days ago
$2,317
Roundtrip
found 3 days ago
Select South African Airways flight, departing Sun, Jan 11 from Cape Town to São Tomé Island, returning Sun, Jan 18, priced at $2,317 found 3 days ago
Sun, Jan 11 - Sun, Jan 18
CPT
Cape Town
TMS
São Tomé Island
$2,366 Roundtrip, found 3 days ago
$2,366
Roundtrip
found 3 days ago
Select TAAG Angola Airlines flight, departing Sun, Jan 11 from Cape Town to São Tomé Island, returning Sun, Jan 18, priced at $2,366 found 3 days ago
Sun, Jan 11 - Sun, Jan 18
CPT
Cape Town
TMS
São Tomé Island
$2,397 Roundtrip, found 3 days ago
$2,397
Roundtrip
found 3 days ago
Select South African Airways flight, departing Sun, Jan 11 from Cape Town to São Tomé Island, returning Sun, Jan 18, priced at $2,397 found 3 days ago

Hotel Ideas near São Tomé Intl.

Airport Hotels near São Tomé Intl.

Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
$196 nightly
The price is $229 total per night from Jan 4 to Jan 5
$229 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
9.4/10 Exceptional! (62 reviews)
Staff was very friendly. Food was excellent. Room was clean and well kept.

Reviewed on Dec 4, 2025

Omali São Tomé – Principe Collection
Hotel Praia

Hotel Praia

3.5 out of 5
Praia Lagarto - Cx. Postal 61 São Tomé
$148 nightly
The price is $174 total per night from Jan 12 to Jan 13
$174 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon ...
7.2/10 Good! (18 reviews)
Pros: Room is very spacious and clean. Common areas also nice and generally I enjoyed a quiet atmosphere. Staff is nice, food is good. Cons: They did not honor the complementary airport transfer that is announced on line, they arranged a private taxi that charged me 20 US Dollars (for a 4 minute ...

Reviewed on Dec 6, 2023

Hotel Praia
Praia Accommodation

Praia Accommodation

3 out of 5
Praia Lagarto São Tomé São Tomé
$128 nightly
The price is $147 total per night from Jan 15 to Jan 16
$147 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
Book a stay at this beach B&B in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
Great place to stay

Reviewed on Nov 21, 2024

Praia Accommodation
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In São Tomé Island

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
$206 nightly
The price is $236 total per night from Jan 4 to Jan 5
$236 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this luxury hotel in São Tomé. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Estadio Nacional 12 de Julho and Cloçon ...
8/10 Very Good! (78 reviews)
Wonderful stay, great staff, easy, relaxing delightful.

Reviewed on Dec 9, 2025

Pestana São Tomé
Hotel Central

Hotel Central

3.5 out of 5
Rua de Angola São Tomé São Tomé
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and an airport shuttle (surcharge). Popular attractions Cloçon Téla ...
8/10 Very Good! (24 reviews)
On my last night, I was locked out and couldn't open the outside door to enter the hotel. I tried to contact the hotel using the phone number provided on Expedia, but it wasn't updated. As a result, I had to stay at a friend's house for the night.

Reviewed on Nov 7, 2024

Get rates
Hotel Central
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
$196 nightly
The price is $229 total per night from Jan 4 to Jan 5
$229 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
9.4/10 Exceptional! (62 reviews)
Staff was very friendly. Food was excellent. Room was clean and well kept.

Reviewed on Dec 4, 2025

Omali São Tomé – Principe Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CPT to TMS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
CPT Address & GPS
Address:
Cape Town ,
South Africa
IATA Code:
CPT
Longitude:
18.596489
Latitude:
-33.968906
Time Zone:
Africa/Johannesburg
TMS Address & GPS
Address:
Sao Tome Island ,
Sao Tome and Principe
IATA Code:
TMS
Longitude:
6.725
Latitude:
0.378333
Time Zone:
Africa/Sao_Tome

Frequently asked questions

What is the shortest flight from Cape Town Intl. Airport to Sao Tome Intl. Airport?
Take the opportunity to sit back and chill out on your way from Cape Town to São Tomé Island. The fastest flight time from Cape Town Intl. Airport to TMS is 6 hours and 20 minutes, which gives you loads of time to enjoy a beverage or get swept up in a good movie.
How many hours flight from Cape Town Intl. Airport to TMS?
From CPT to TMS, you'll be cruising the skies for about 6 hours and 20 minutes. Settle in, grab a wine and put on your noise-canceling earphones. It's time for a binge-watching session.
What airlines have the most flights from Cape Town Intl. Airport (CPT) to Sao Tome Intl. Airport (TMS)?
For now, there are no airlines that fly direct from CPT to TMS. But never fear. There are plenty of single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.