Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

3.0 star property
Hotel in Sioux Falls with a 24-hour fitness center and an indoor pool

Choose dates to view prices

Photo gallery for Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Terrace/patio
Fridge, microwave, dishwasher, coffee/tea maker
Studio Suite, 1 King Bed, Non Smoking | Living area | LCD TV
Suite, 1 Bedroom, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Indoor pool

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
1120 S Grange Ave, Sioux Falls, SD, 57105
  • Place, Sanford USD Medical Center
    ‪1 min walk‬
  • Place, University of Sioux Falls
    ‪5 min walk‬
  • Place, Augustana College
    ‪11 min walk‬
  • Airport, Sioux Falls, SD (FSD-Sioux Falls Regional)
    ‪7 min drive‬

Room options

Studio Suite, 1 King Bed, Non Smoking

9.4 out of 10
Exceptional
(24 reviews)
  • 435 sq ft
  • Sleeps 4
  • 1 King Bed

Studio, 2 Queen Beds, Non Smoking

9.4 out of 10
Exceptional
(12 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds

Suite, 1 Bedroom, Non Smoking

10.0 out of 10
Exceptional
(2 reviews)
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

Studio, 1 King Bed, Accessible, Non Smoking

10.0 out of 10
Exceptional
(2 reviews)
  • 435 sq ft
  • Sleeps 4
  • 1 King Bed

Studio, 1 King Bed, Accessible, Bathtub

9.6 out of 10
Exceptional
(4 reviews)
  • 430 sq ft
  • Sleeps 4
  • 1 King Bed

Studio, 2 Queen Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(4 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds

Studio, 2 Queen Beds, Accessible, Bathtub

9.0 out of 10
Wonderful
(2 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds

Studio, 2 Queen Beds, Accessible, Non Smoking

9.2 out of 10
Wonderful
(5 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds

Suite, 1 King Bed, Accessible, Bathtub

10.0 out of 10
Exceptional
(1 review)
  • 527 sq ft
  • Sleeps 4
  • 1 King Bed

Suite, 1 King Bed, Accessible, Non Smoking

  • 530 sq ft
  • Sleeps 4
  • 1 King Bed

Suite, 1 King Bed, Accessible, Non Smoking

  • 530 sq ft
  • Sleeps 4
  • 1 King Bed

King Studio Suite-Non-Smoking

  • Sleeps 4

King Suite-Accessible Roll In Shower-Non-Smoking

  • Sleeps 4

One-Bedroom King Suite-Non-Smoking

  • Sleeps 4

Studio With 2 Queen Beds-Non-Smoking

  • Sleeps 6

Mobility Hearing Access King Suite with tub

  • Sleeps 4

hearing Access King Studio Suite

  • Sleeps 4

Hearing Access Two Queen Studio Suite

  • Sleeps 6

Access Two Queen Studio with Roll in Shower

  • Sleeps 6

Access Two Queen Studio with Tub

  • Sleeps 6

King Studio Suite With Accessible Tub-Non-Smoking

  • Sleeps 4

King Suite-Hearing Accessible-Non-Smoking

  • Sleeps 4

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About the neighborhood

Sioux Falls

Located in University Heights, Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is adjacent to Sanford USD Medical Center and within a 5-minute walk of Sioux Empire Medical Museum. This 80-room, 3-star hotel has free breakfast along with conveniences like an indoor pool and a 24-hour gym.

What's nearby

  • Sanford USD Medical Center - 1 min walk - 0.1 miles
  • University of Sioux Falls - 5 min walk - 0.3 miles
  • Augustana College - 11 min walk - 0.6 miles
  • Washington Pavilion of Arts and Science - 2 min drive - 1.1 miles
  • Falls Park - 3 min drive - 1.5 miles

Getting around

  • Sioux Falls Regional Airport (FSD) - 8 min drive

Restaurants

  • ‪Fryn' Pan - ‬2 min drive
  • ‪Taco John's - ‬3 min drive
  • ‪Giliberto's Mexican Taco Shop - ‬14 min walk
  • ‪Taco Bell - ‬13 min walk
  • ‪Slim Chickens - ‬16 min walk

About this property

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Hotel in Sioux Falls with a 24-hour fitness center and an indoor pool
Guests staying at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include conference space, a business center, and express check-out.
42-inch LCD TVs are available for entertainment, and guests can stay connected with free WiFi. Other standard amenities include kitchens, sofa beds, and refrigerators. Weekly housekeeping is available.
Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Free in-room WiFi has a 3-device limit
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free on-the-go breakfast available daily 6:00 AM to 9:00 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Indoor pool
  • Laundry facilities
  • Living room

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Housekeeping (weekly)

Business services

  • 950 square feet of conference space
  • Business center

Outdoors

  • Barbecue grill

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Braille/raised signage
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 4 floors
  • Built in 2014
  • Designated smoking areas (fines apply)

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed

Bathroom

  • Private bathroom
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 42-inch LCD TV

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Iron/ironing board
  • Living room
  • Phone

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 11:00 PM
Early check-in subject to availability
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Late check-out subject to availability
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
This property doesn't offer after-hours check-in
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 50 per accommodation, per stay
  • Dogs and cats only
  • 2 total (50 lbs is the maximum weight per pet)
  • Service animals exempt from fees

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 50 per accommodation, per stay
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Noise-free guestrooms cannot be guaranteed
  • Check-in: 3:00 PM
  • Check-out: noon
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking out is easy with express services. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards, debit cards, and cash.

Additional information about polices, regulations, and more:

  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.
  • Noise-free rooms can't be guaranteed.
  • Free in-room WiFi has a 3-device limit.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Home2 Suites Hilton Sioux Falls/Sanford Hotel
Home2 Suites Hilton Falls/Sanford Hotel
Home2 Suites Hilton Sioux Falls/Sanford
Home2 Suites Hilton Sioux Falls/Sanford Hotel
Home2 Suites Hilton Falls/Sanford Hotel
Home2 Suites Hilton Sioux Falls/Sanford
Home2 Suites Hilton Falls/Sanford
Hotel Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center Hotel

Frequently asked questions

Are free cancellation options available at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offers free cancellation on some room rates. For additional details, look at the cancellation policy on our site.

How much does it cost to stay at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

As of Jan 31, 2026, prices found for a 1-night stay for 2 adults at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center on Feb 8, 2026 start from $105.78, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do within easy reach of Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

This hotel is situated in University Heights, just steps from Sioux Empire Medical Museum. You'll also find Denny Sanford Premier Center and Great Plains Zoo within a short drive.

Will I be able to park at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a casino at the property?

No, Home2 Suites By Hilton Sioux Falls/Sanford Medical Center doesn't have a casino.

Is there an indoor pool at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Yes, this hotel has an indoor pool.

What will couples enjoy most about a stay at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Couples staying at this hotel will appreciate amenities like a kitchen as well as an indoor pool and a 24-hour fitness facility.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a hot tub?

No, this hotel doesn't have a spa tub.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a restaurant that serves breakfast?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offers free on-the-go breakfast each morning though there is no restaurant.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center allow pets to stay free of charge?

Although they can't stay for free, cats and dogs are welcome at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center for a fee of USD 50 per accommodation, per stay.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have connecting rooms?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

What is the closest airport to Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

The closest major airport to Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is Sioux Falls Regional Airport (FSD), which is 4 mi away (8 minutes by car).

Are there rooms with balconies at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

No, there aren't any guestrooms with balconies at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center.

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 457 out of 602 reviews
Rating 8 - Good. 103 out of 602 reviews
Rating 6 - Okay. 26 out of 602 reviews
Rating 4 - Poor. 9 out of 602 reviews
Rating 2 - Terrible. 7 out of 602 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Myla

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and comfortable
Stayed 1 night in Dec 2025

10/10 Excellent

Kari

Liked: Cleanliness, amenities, property conditions & facilities
Yes
Stayed 1 night in Oct 2025

10/10 Excellent

Cher

Traveled with pets, Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Yes
Stayed 1 night in Sep 2025

10/10 Excellent

Colin

Stayed 4 nights in Oct 2025

8/10 Good

Anita

Traveled with partner, Traveled with pets
Liked: Cleanliness, amenities, property conditions & facilities
The staff was so welcoming and the room was spotless
Stayed 1 night in Oct 2025

10/10 Excellent

Kent Van

Stayed 1 night in Oct 2025

10/10 Excellent

Sara

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We loved our stay at Home2. Destynee checked us in and was such a friendly face at the desk. The rest of the staff also had excellent customer service. Our room and the entore hotel was clean. When we needed anything, we reached out and were quickly helped.
Stayed 4 nights in Oct 2025

10/10 Excellent

Patrick

Stayed 2 nights in Oct 2025

10/10 Excellent

Judge Sheva

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
👍👍👍
Stayed 2 nights in Oct 2025

10/10 Excellent

Mary

Stayed 3 nights in Oct 2025

8/10 Good

Corene

Stayed 2 nights in Oct 2025

10/10 Excellent

Todd

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Sep 2025

10/10 Excellent

Vikki

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The stat was pleasant and conveniently attached to the Sanford hospital. So nice to be able to walk to visit patient and back to hotel room. Rooms were nice and clean. Pool was a plus for the kids. Staff was very friendly.
Stayed 2 nights in Sep 2025

10/10 Excellent

CAROLYN

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Hair on floor in bathroom. Kitchen had dirt on counter.
Stayed 3 nights in Sep 2025

10/10 Excellent

Ellen

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Katherine

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The cleanest hotel I’ve been to. Very quiet and nice.
Stayed 2 nights in Sep 2025

10/10 Excellent

Mindy

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Sep 2025

10/10 Excellent

Kylie

Stayed 2 nights in Jul 2025

10/10 Excellent

Traci

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
On a college visit to USF and Augustana. Great place to stay. In walking distance to both schools.
Stayed 1 night in Sep 2025

6/10 Okay

Nicole

Stayed 1 night in Aug 2025

10/10 Excellent

Jeremy

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property is very clean and conveniently attached to Sanford Hospital.
Stayed 1 night in Aug 2025

8/10 Good

Katelyn

Liked: Staff & service, property conditions & facilities
Stayed 1 night in Jul 2025

10/10 Excellent

Elizabeth

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
They really helped us in a time of need. The staff were always so quick to accommodate our needs and requests. Thank you for your empathy in our difficult circumstance! It made having a place outside the hospital a refuge to get refreshed to go back to what we needed to do.
Stayed 2 nights in Jul 2025

8/10 Good

Adam

Stayed 1 night in Jun 2025

6/10 Okay

Kristi

Stayed 1 night in Jul 2025