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Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with a fitness center and a 24-hour front desk

Choose dates to view prices

Photo gallery for Comfort Inn & Suites Sikeston I-55

Experience the sleek design of this hotel, featuring a flat roof and modern architecture.
Swimmers can enjoy a rectangular pool with designated lanes and a lifeguard stand.
Welcome to the reception area, where a friendly staff is available to assist with your stay.
Two double beds with wooden headboards and white bedding, a bedside table with a lamp and telephone, and a comfortable chair by the window.
Enjoy a well-equipped kitchen with a coffee machine, microwave, and kettle, perfect for preparing a morning coffee or snack.

Reviews

8.4 out of 10
Very good

Popular amenities

  • Gym
  • Laundry
  • Pet friendly
  • Parking included
  • Free WiFi

Explore the area

View in a map
109 Matthews Ln, Sikeston, MO, 63801
  • City of Miner Convention Center
    ‪5 min walk‬
  • Central Park
    ‪5 min drive‬
  • Sikeston Depot Museum
    ‪6 min drive‬
  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪31 min drive‬

Room options

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Relax in this cozy space with a single bed, sofa, and desk, perfect for a comfortable stay.

Suite, 1 King Bed with Sofa bed, Non Smoking

  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Standard Room, 2 Queen Beds, Non Smoking

Enjoy a comfortable stay with two beds, a flat-screen TV, and convenient amenities like a microwave and coffee maker.

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Enjoy a comfortable stay with two beds, a flat-screen TV, and convenient amenities like a microwave and coffee maker.

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Relax in comfort with a large bed, a nightstand, and a cozy reading chair.

Room, 1 King Bed, Accessible, Non Smoking

9.0 out of 10
Wonderful
(2 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Non Smoking

Relax in comfort with a large bed, a nightstand, and a cozy reading chair.

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)
  • Sleeps 2
  • 1 King Bed

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About the neighborhood

Sikeston

Located within a leisurely stroll of City of Miner Convention Center, Comfort Inn & Suites Sikeston I-55 is within a 10-minute drive of Sikeston Depot Museum. This 64-room hotel welcomes guests with conveniences like an indoor pool, free in-room WiFi, and free self parking.

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.3 miles
  • Central Park - 5 min drive - 3.5 miles
  • Sikeston Depot Museum - 6 min drive - 3.5 miles
  • Southeast Missouri State University - 41 min drive - 37.6 miles
  • Isle Casino Cape Girardeau - 42 min drive - 38.0 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Caf - ‬17 min walk
  • ‪Taco Bell - ‬6 min drive
  • ‪Buffalo Wild Wings - ‬5 min drive
  • ‪Jay's Krispy Fried Chicken - ‬5 min drive
  • ‪McDonald's - ‬3 min walk

About this property

Comfort Inn & Suites Sikeston I-55

Hotel in Sikeston with a fitness center and a 24-hour front desk
At Comfort Inn & Suites Sikeston I-55, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center and laundry facilities.
Guests can expect to find free WiFi. Other amenities include coffee makers, phones, and desks.
Recreational amenities at the hotel include an indoor pool and a fitness center.

Languages

English, Hindi

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Best Western Plus Sikeston

  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
8.4 out of 10, Very Good, 1,002 reviews
$88 nightly
The price is $100
Aug 17 - Aug 18
Total includes taxes and fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: anytime
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 20 per pet, per night
  • Dogs and cats only
  • 2 total (20 lbs is the maximum weight per pet)
  • Certain rooms only
  • Guests can request a pet-friendly room by contacting the property at the number on the booking confirmation
  • Service animals exempt from fees

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
  • Check-in: 2:00 PM
  • Check-out: 11:00 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

Additional information about polices, regulations, and more:

  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

Is free cancellation available at Comfort Inn & Suites Sikeston I-55?

Comfort Inn & Suites Sikeston I-55 provides free cancellation on some room rates. For additional details, look at the cancellation policy on our site.

What's there to do close to Comfort Inn & Suites Sikeston I-55?

This hotel is located in Sikeston, close to Central Park and Sikeston Depot Museum.

Will I be able to park at Comfort Inn & Suites Sikeston I-55?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Does Comfort Inn & Suites Sikeston I-55 have a casino?

No, Comfort Inn & Suites Sikeston I-55 doesn't have a casino.

Is there an indoor pool at Comfort Inn & Suites Sikeston I-55?

Yes, this hotel has an indoor pool.

Is Comfort Inn & Suites Sikeston I-55 a good place to stay for couples?

Amenities at this hotel that appeal to couples include an indoor pool and a 24-hour front desk.

Does Comfort Inn & Suites Sikeston I-55 have a hot tub?

No, this hotel doesn't have a spa tub.

Does Comfort Inn & Suites Sikeston I-55 have a restaurant that serves breakfast?

No, Comfort Inn & Suites Sikeston I-55 doesn't have a restaurant that serves breakfast.

Does Comfort Inn & Suites Sikeston I-55 allow pets to stay for free?

Although they can't stay for free, cats and dogs are welcome at Comfort Inn & Suites Sikeston I-55 for a fee of USD 20 per pet, per night.

Does Comfort Inn & Suites Sikeston I-55 have connecting rooms?

No, there aren't connecting guestrooms at this hotel.

How far is the airport from Comfort Inn & Suites Sikeston I-55?

The closest major airport to Comfort Inn & Suites Sikeston I-55 is Cairo, IL (CIR-Cairo Regional), which is 28.1 mi away (29 minutes by car). Another top airport is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is located 26.7 mi away (29-minute drive).

Are there rooms with balconies at Comfort Inn & Suites Sikeston I-55?

No, there aren't any guestrooms with balconies at Comfort Inn & Suites Sikeston I-55.

Comfort Inn & Suites Sikeston I-55 Reviews

Reviews

8.4

Very Good

Rating 10 - Excellent. 125 out of 271 reviews
Rating 8 - Good. 91 out of 271 reviews
Rating 6 - Okay. 28 out of 271 reviews
Rating 4 - Poor. 18 out of 271 reviews
Rating 2 - Terrible. 9 out of 271 reviews

8.4/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.2/10

Property conditions & facilities

8.2/10

Eco-friendliness

Reviews

8/10 Good

John

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good stay

It was decent…slept well The room was clean
Stayed 1 night in May 2025

8/10 Good

Luther

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Feb 2025

10/10 Excellent

Sharon

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice
Stayed 1 night in Apr 2025

10/10 Excellent

Allan

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

10/10 Excellent

Meaghan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

8/10 Good

Frank

Stayed 2 nights in Apr 2025

10/10 Excellent

Marsha

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was okay, quiet and helpful.
Stayed 1 night in Apr 2025

8/10 Good

Sheila a

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quiet

Clean enough though older. Main thing for me was peace and quiet so I could sleep during the day ( working nights while in town). That was great!
Stayed 2 nights in Mar 2025

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Mar 2025

6/10 Okay

Mary Jane

Traveled with partner
Disliked: Property conditions & facilities
In need of maintenance
Stayed 1 night in Mar 2025

10/10 Excellent

Kimberly

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were in town for a pit-stop to sleep and the staff was very nice. Comfy beds and nice location
Stayed 1 night in Mar 2025

10/10 Excellent

Marsha

Liked: Property conditions & facilities
Very clean! Bed and pillows comfortable. Pool and hot tub was nice. They had plenty of pool towels. Breakfast was okay. They had the normal breakfast but the eggs and sausage was fake. The waffles never disappoint. McDonald’s right next store if you want. Very impressed with this place. Would definitely recommend.
Stayed 1 night in Mar 2025

8/10 Good

Amanda

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel with great staff. Room was fine, breakfast could be better but overall a good stay for this area.

10/10 Excellent

Brenda

Liked: Cleanliness, property conditions & facilities, room comfort

Darrel was awesome!

Stay was good. TV wouldn’t work, Darrel came up and fixed it right away. Very nice young man.
Stayed 1 night in Mar 2025

8/10 Good

Denise

Business traveler
hotel was fine clean and convient
Stayed 1 night in Feb 2025

8/10 Good

Walter

Liked: Cleanliness, staff & service, property conditions & facilities
Good place to spend a night
Stayed 1 night in Mar 2025

10/10 Excellent

Debra

Traveled with group, Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Feb 2025

10/10 Excellent

Margaret

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Thank you

Great stay, quiet, friendly and just what we expected!
Stayed 1 night in Feb 2025

10/10 Excellent

Mike

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, and available rooms when we needed it most due to storms
Stayed 1 night in Feb 2025

10/10 Excellent

Diane

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice helpful young man checked us in. And help with our TV connection!
Stayed 1 night in Feb 2025

10/10 Excellent

George

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Roger

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice spacious rooms. Beds were very comfortable. Quiet place.
Stayed 1 night in Jan 2025

10/10 Excellent

Ruth Ann

Stayed 1 night in Sep 2024

8/10 Good

Tamra

Liked: Cleanliness, staff & service, property conditions & facilities
Needs diet soda option in the vending machine
Stayed 1 night in Dec 2024

10/10 Excellent

Michael, Chicago

Liked: Cleanliness, staff & service, property conditions & facilities
Conveniant to I55, clean, and comfortable,
Stayed 1 night in Dec 2024

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