Hotels with Restaurants in Orangeburg
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Featured Orangeburg Hotels with Restaurants

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $131 total per night
$131 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.

Spark by Hilton Orangeburg
731 Citadel Road Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$87 nightly
The price is $97 total per night
$97 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
Renovated in 2025, Spark by Hilton Orangeburg offers a gym, free WiFi in public areas, and a seasonal outdoor pool. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, express check-out, and a terrace.
Pool
Breakfast included

Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$55 nightly
The price is $61 total per night
$61 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Guests of Baymont by Wyndham Orangeburg North enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this adults-only hotel include coffee/tea in a common area, express check-out, and laundry facilities.

Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$132 nightly
The price is $147 total per night
$147 total
Jan 22 - Jan 23, 2026
Total with taxes and fees
At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.

Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
Free Cancellation
$122 nightly
The price is $135 total per night
$135 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.

Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $78 total per night
$78 total
Dec 30 - Dec 31
Total with taxes and fees
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a vending machine.

Hampton Inn & Suites Orangeburg
749 Citadel Road Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$130 nightly
The price is $145 total per night
$145 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
Guests of Hampton Inn & Suites Orangeburg have access to an outdoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and express check-in.

Travelodge by Wyndham Orangeburg
3620 Saint Matthews Rd Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$79 nightly
The price is $88 total per night
$88 total
Dec 30 - Dec 31
Total with taxes and fees
Travelodge by Wyndham Orangeburg features free WiFi in public areas, coffee in a common area, and express check-out. Free parking is available if you drive. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free motel also has a vending machine.

Comfort Inn & Suites Santee
221 Britain St Santee SC
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $117 total per night
$117 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.

Baymont by Wyndham Santee
249 Britain Street Santee SC
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $83 total per night
$83 total
Dec 30 - Dec 31
Total with taxes and fees
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.

Comfort Inn & Suites Orangeburg
746 Citadel Rd Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$95 nightly
The price is $106 total per night
$106 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At Comfort Inn & Suites Orangeburg, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and tours or tickets. Additional amenities include a business center, a meeting room, and express check-out.

Days Inn by Wyndham Orangeburg
3691 Saint Matthews Rd Orangeburg SC
$46 nightly
The price is $51 total per night
$51 total
Dec 30 - Dec 31
Total with taxes and fees
Guests of Days Inn by Wyndham Orangeburg enjoy free WiFi in public areas, a business center, and express check-out. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities and a vending machine.

Super 8 by Wyndham Santee
9125 Old Highway 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $83 total per night
$83 total
Dec 30 - Dec 31
Total with taxes and fees
Guests of Super 8 by Wyndham Santee enjoy access to free WiFi in public areas, meeting rooms, and a business center. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Other amenities at this golf motel include a seasonal outdoor pool, express check-in, and express check-out.

Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $68 total per night
$68 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Travelodge by Wyndham Santee features free WiFi in public areas, a business center, and coffee in a common area. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables and tours/tickets. Additional amenities include an ATM and a vending machine.

Holiday Inn Express & Suites Orangeburg by IHG
118 Sleep Inn Road Orangeburg SC
Free Cancellation
$118 nightly
The price is $131 total per night
$131 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
At Holiday Inn Express & Suites Orangeburg by IHG, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and express check-out.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Orangeburg hotels essential information
Accommodation | 254 hotels |
|---|---|
Lowest Price | $51 |
Highest Price | $147 |
Popular hotels | Best Western Plus Santee Inn, Spark by Hilton Orangeburg, Baymont by Wyndham Orangeburg North, Hampton Inn Santee-I-95, Holiday Inn Santee by IHG, Red Roof Inn Santee, Hampton Inn & Suites Orangeburg, Travelodge by Wyndham Orangeburg, Comfort Inn & Suites Santee, Baymont by Wyndham Santee, Comfort Inn & Suites Orangeburg, Days Inn by Wyndham Orangeburg, Super 8 by Wyndham Santee, Travelodge by Wyndham Santee, Holiday Inn Express & Suites Orangeburg by IHG |
Recent Hotels with Restaurants Reviews

Tru by Hilton Orangeburg
5/5 Excellent
"We were greatly quickly as soon as we came in. The clerk was very informative and so sweet . We had a pet and a disabled child with us and she placed us on the ground level. Worked perfectly for our family. Thank you for allowing pets to be included in our stay. Your hotel is very fresh and clean. Definitely will book again. "
A verified traveler stayed at Tru by Hilton Orangeburg
Posted 1 day ago
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