Hotels in Mesopotamia

Search over 491 hotels from $39

Start date: Check-in selected.
To Date
End date: Check-out

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Top Rated Mesopotamia Hotels

Don't see what you're looking for?
See all available properties in Mesopotamia
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Mesopotamia hotels options

    Hotel Saint George

    Hotel Saint George

    Avenida Cordoba 148 Puerto Iguazú Misiones
    $141 nightly
    The price is $145 total per night from Jan 10 to Jan 11
    $145 total
    Jan 10 - Jan 11, 2026
    8.6/10 Excellent! (1,003 reviews)
    Hotel Nacional Inn Foz do Iguaçu

    Hotel Nacional Inn Foz do Iguaçu

    Rod. Das Cataratas, Km 16,7 Foz do Iguaçu PR
    $101 nightly
    The price is $106 total per night from Jan 18 to Jan 19
    $106 total
    Jan 18 - Jan 19, 2026
    Total with taxes and fees
    8/10 Very Good! (653 reviews)
    Residencial Los Lapachos

    Residencial Los Lapachos

    Los Lapachos Nº 584 Puerto Iguazú Misiones
    Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

    Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

    Rodovia Br 469 Km 32 Foz do Iguaçu PR
    $858 nightly
    The price is $897 total per night from Jan 17 to Jan 18
    $897 total
    Jan 17 - Jan 18, 2026
    Total with taxes and fees
    9.8/10 Exceptional! (1,003 reviews)
    La Reserva Virgin Lodge

    La Reserva Virgin Lodge

    Ruta 12 km 5 Puerto Iguazú Misiones
    8.4/10 Very Good! (802 reviews)
    Hotel Colonial Iguaçu

    Hotel Colonial Iguaçu

    Rod. das Cataratas, Km 20 Foz do Iguaçu PR
    $112 nightly
    The price is $118 total per night from Jan 19 to Jan 20
    $118 total
    Jan 19 - Jan 20, 2026
    Total with taxes and fees
    7.6/10 Good! (753 reviews)
Mesopotamia Hotels

Orbitz makes it easy to find the best Mesopotamia hotel deals for your trip. With an outstanding selection, easy-to-use search tools and descriptive hotel profiles, you'll find Mesopotamia hotel deals in a wink..

Great selection of hotels in Mesopotamia

Whether you're searching for hotels in Mesopotamia on business, or hunting for a family getaway, Mesopotamia hotel options are only a click away. Find hotels in Mesopotamia with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Mesopotamia hotels close you are to the airport and nearby attractions.

Mesopotamia hotel reviews, photos and virtual tours

Thanks to photos and virtual tours, you can look before you book your Mesopotamia hotel reservation. Check out Mesopotamia hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Mesopotamia with unbiased reviews from verified Mesopotamia hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

Grab Mesopotamia hotel deals and special offers

Orbitz works around the clock to find exclusive offers and Mesopotamia hotel deals, just for you. Sign up for deals by e-mail where you'll get first crack at money-saving extras like promo codes, resort credits, free nights and more. You can also "Like" Orbitz on Facebook and follow us on Twitter to receive up-to-the-minute news on hotel discounts, giveaways and more.

24/7 support with Mesopotamia hotel reservations

When it comes to finding hotels in Mesopotamia, an Orbitz specialist can help you find the property right for you. Chat live or call 1-800-454-3743 any time for help booking your hotels in Mesopotamia. Our team of experts can help you pinpoint Mesopotamia hotels options suited to your tastes and budget.

Forget Orbitz change or cancel fees on Mesopotamia hotels

On Orbitz, Mesopotamia hotel deals mean flexibility. If you need to change your Mesopotamia hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to Mesopotamia all in one place.

 

Mesopotamia hotels essential information

Accommodation
491 hotels
Lowest Price
$39
Highest Price
$897
Popular hotels
Marriott Corrientes Hotel, O2 Hotel Gualeguaychú, Totoras Apart Federacion, Hathor Concordia, Intersur Colon, Club Valle Termal Resort, La Casona de Susana, Casa del Árbol, Hotel y Spa Termas del Este, COSTA NORTE HOSTERIA, La Alondra Casa De Huéspedes, Holiday Inn Express Rosario by IHG

Recent Reviews