See all properties

Comfort Inn & Suites - Hannibal

2.5 star property
Hotel in Hannibal with a full-service spa and a 24-hour fitness center

Choose dates to view prices

Photo gallery for Comfort Inn & Suites - Hannibal

In-room safe, desk, blackout drapes, iron/ironing board
Indoor pool, sun loungers
Lobby
Free daily buffet breakfast
Exterior

Reviews

7.6 out of 10
Good

Popular amenities

  • Hot tub
  • Pet friendly
  • Parking included

Explore the area

View in a map
4000 Market St, Hannibal, MO, 63401
  • Place, Indian Mounds Park
    ‪4 min drive‬
  • Place, Rockcliffe Mansion
    ‪5 min drive‬
  • Place, Mark Twain Boyhood Home and Museum
    ‪6 min drive‬
  • Airport, Quincy, IL (UIN-Quincy Regional-Baldwin Field)
    ‪34 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Non Smoking

In-room safe, desk, blackout drapes, iron/ironing board

Standard Room, 2 Queen Beds, Non Smoking

9.0 out of 10
Wonderful
(17 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 1 King Bed, Non Smoking

Room, 1 King Bed, Non Smoking | In-room safe, desk, blackout drapes, iron/ironing board

Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(24 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 Queen Bed, Accessible, Non Smoking

In-room safe, desk, blackout drapes, iron/ironing board

Room, 1 Queen Bed, Accessible, Non Smoking

8.4 out of 10
Very good
(7 reviews)
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

In-room safe, desk, blackout drapes, iron/ironing board

Suite, 1 King Bed with Sofa bed, Non Smoking

  • Sleeps 4
  • 1 King Bed and 1 Twin Sofa Bed

View all photos for Efficiency, Suite, 1 King Bed with Sofa bed, Non Smoking

In-room safe, desk, blackout drapes, iron/ironing board

Efficiency, Suite, 1 King Bed with Sofa bed, Non Smoking

8.8 out of 10
Excellent
(3 reviews)
  • Sleeps 4
  • 1 King Bed and 1 Twin Sofa Bed

View all photos for Room, 1 Queen Bed, Non Smoking

In-room safe, desk, blackout drapes, iron/ironing board

Room, 1 Queen Bed, Non Smoking

8.0 out of 10
Very good
(3 reviews)
  • Sleeps 2
  • 1 Queen Bed

View all photos for Room, 1 Queen Bed, Accessible, Non Smoking

In-room safe, desk, blackout drapes, iron/ironing board

Room, 1 Queen Bed, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency, Upgrade)

In-room safe, desk, blackout drapes, iron/ironing board

Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency, Upgrade)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 2 Queen Beds, Non Smoking

In-room safe, desk, blackout drapes, iron/ironing board

Room, 2 Queen Beds, Non Smoking

7.6 out of 10
Good
(11 reviews)
  • Sleeps 4
  • 2 Queen Beds

About the neighborhood

Hannibal

Comfort Inn & Suites - Hannibal is located within a few miles (5 km) of Sodalis Nature Preserve and West Ely Park. This 74-room hotel welcomes guests with conveniences like free breakfast, a full-service spa, and an indoor pool.

What's nearby

  • Indian Mounds Park - 4 min drive - 2.8 miles
  • Rockcliffe Mansion - 5 min drive - 3.2 miles
  • Mark Twain Memorial Lighthouse - 6 min drive - 4.3 miles
  • Mark Twain Boyhood Home and Museum - 6 min drive - 3.7 miles
  • Hannibal Regional Hospital - 6 min drive - 5.4 miles

Getting around

  • Quincy, IL (UIN-Quincy Regional-Baldwin Field) - 35 min drive

Restaurants

  • ‪McDonald's - ‬5 min drive
  • ‪Taco Bell - ‬5 min drive
  • ‪Coffee Barn - ‬6 min drive
  • ‪El Vaquero - ‬6 min drive
  • ‪Sonic Drive-In - ‬5 min drive

About this property

Comfort Inn & Suites - Hannibal

Hotel in Hannibal with a full-service spa and a 24-hour fitness center
Comfort Inn & Suites - Hannibal features a full-service spa, an indoor pool, and a 24-hour gym. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this spa hotel include free WiFi in public areas, a hot tub, and conference space.
Guests can enjoy flat-screen TVs and stay connected with free WiFi. Bathrooms offer hydromassage showers, hair dryers, and free toiletries. Refrigerators, microwaves, and coffee makers are also available.
An indoor pool and a hot tub are on site. Other recreational amenities include a 24-hour fitness center.

The recreational activities listed below are available either on site or nearby; fees may apply.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Similar properties

Lobby
Quality Inn & Suites Hannibal West
  • Pool
  • Hot tub
  • Breakfast included
  • Pet friendly
8.0 out of 10, Very Good, 1,005 reviews
$66 nightly
The price is $76
Feb 19 - Feb 20
Total with taxes and fees
Quality Inn & Suites Hannibal West

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • RV/bus/truck parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Full-service spa
  • Hot tub
  • Indoor pool

Family friendly

  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Laundry facilities
  • Safe at front desk
  • Vending machine

Guest services

  • Housekeeping (daily)

Business services

  • 1,200 square feet of conference space
  • Business center
  • Meeting room

Outdoors

  • Picnic area
  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator
  • Grab bar in bathtub
  • Handrails in stairways
  • Lever door handles
  • Low-height counter and sink
  • Low-height door lock
  • Low-height view port in door
  • Phone accessibility kit
  • Portable bathtub seat
  • Visual alarms in hallways
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking
  • Wheelchair-width doorways

More

  • 3 floors
  • Banquet hall
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Hydromassage showerhead
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • Flat-screen TV

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning
  • Desk
  • Free local calls
  • Free weekday newspapers
  • Heating
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight

Check-out

Check-out before 11 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 27.22 per pet, per day
  • Dogs and cats only
  • Service animals exempt from fees

Property payment types

Important information

Fees

  • Service fee: USD 3 per accommodation, per night

These are all of the charges provided to us by the property.

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 27.22 per pet, per day
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
  • Check-in: 3 PM
  • Check-out: 11 AM
The front desk is open 24 hours a day. Driving? This property offers free self parking, along with RV, bus, and truck parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

Additional information about polices, regulations, and more:

  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.

Property is also known as

Comfort Inn Hotel Hannibal
Comfort Inn Hannibal
Comfort Inn Suites Hannibal
Holiday Inn Express Suites Hannibal

Frequently asked questions

Is free cancellation available at Comfort Inn & Suites - Hannibal?

Comfort Inn & Suites - Hannibal provides free cancellation on select room rates. For specific requirements, review the cancellation policy on Orbitz.

How much does it cost to stay at Comfort Inn & Suites - Hannibal?

As of Feb 8, 2026, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites - Hannibal on Mar 8, 2026 start from $71.68, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What can I see within easy reach of Comfort Inn & Suites - Hannibal?

This hotel is located in Hannibal, close to Rockcliffe Mansion, Jim's Journey: The Huck Finn Freedom Center, and Mark Twain Boyhood Home and Museum. You'll also find Mississippi River and Mark Twain Memorial Lighthouse within a short drive.

Is there parking available at Comfort Inn & Suites - Hannibal?

Yes, self parking is offered for free at the hotel. Accessible parking and RV/bus/truck parking are also available for guests.

Is there a spa available at Comfort Inn & Suites - Hannibal?

There is a full-service spa at this available for guests to enjoy at this hotel.

Does Comfort Inn & Suites - Hannibal feature a casino at the property?

No, Comfort Inn & Suites - Hannibal doesn't have a casino.

Will I find an indoor pool at Comfort Inn & Suites - Hannibal?

Yes, this hotel has an indoor pool along with a hot tub.

Is Comfort Inn & Suites - Hannibal good for couples?

Couples staying at this hotel will appreciate amenities like a hydromassage showerhead as well as an indoor pool and a full-service spa.

Does Comfort Inn & Suites - Hannibal have a hot tub?

Yes, this hotel has a spa tub.

Does Comfort Inn & Suites - Hannibal have a restaurant with a breakfast menu?

Comfort Inn & Suites - Hannibal offers free buffet breakfast each morning though there is no restaurant.

Will Comfort Inn & Suites - Hannibal allow pets to stay free of charge?

Although they can't stay for free, cats and dogs are welcome at Comfort Inn & Suites - Hannibal for a fee of USD 27.22 per pet, per day.

Are there connecting rooms at Comfort Inn & Suites - Hannibal?

No, there aren't connecting guestrooms at this hotel.

How close is the airport from Comfort Inn & Suites - Hannibal?

The closest major airport to Comfort Inn & Suites - Hannibal is Quincy, IL (UIN-Quincy Regional-Baldwin Field), which is about 20.5 mi away.

Can I book a room with a balcony at Comfort Inn & Suites - Hannibal?

No, at Comfort Inn & Suites - Hannibal, there aren't any guestrooms that list a balcony.

Comfort Inn & Suites - Hannibal Reviews

Reviews

7.6

Good

Rating 10 - Excellent. 247 out of 673 reviews
Rating 8 - Good. 189 out of 673 reviews
Rating 6 - Okay. 113 out of 673 reviews
Rating 4 - Poor. 82 out of 673 reviews
Rating 2 - Terrible. 42 out of 673 reviews

7.6/10

Cleanliness

8.2/10

Staff & service

7.2/10

Amenities

7.2/10

Property conditions & facilities

Reviews

6/10 Okay

Rita

Disliked: Cleanliness, staff & service, amenities
Handicap accessible room. Two lights in entry of room were burned out. The “germ-safe” remote was locked with closed captioning on. Tub not ideal for elderly. Hot tub was old and not clean. Safety rail to hot tub was loose and the lift to get in is rusty.
Stayed 1 night in Nov 2025

8/10 Good

john

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Nah
Stayed 1 night in Oct 2025

8/10 Good

Dennis

Stayed 2 nights in Oct 2025

8/10 Good

Diane

Stayed 1 night in Oct 2025

10/10 Excellent

Jean

Stayed 2 nights in Oct 2025

10/10 Excellent

alexander

Stayed 1 night in Oct 2025

10/10 Excellent

Lori

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Clean room, comfortable bed
Stayed 1 night in Oct 2025

8/10 Good

Kathryn

Stayed 3 nights in Oct 2025

8/10 Good

Heather

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

4/10 Poor

Olena

Stayed 1 night in Oct 2025

6/10 Okay

DEBRA

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
First of all they only allowed 2 very small small bath towels that were very rough not soft if all. Also the breakfast was ok. We went down around 7;45am and they were close to being out of things and the biscuits were maybe the size of a half dollar and the sausage gravy was about gone. Not the best breakfast. One good and nice thing, they did let us check in early which was very nice. Not the best experience but was hard to find a room at a decent price
Stayed 1 night in Oct 2025

2/10 Terrible

Tim

Disliked: Cleanliness, staff & service, property conditions & facilities
Staff was horrible. Everything appeared nice until you use it , ie the hot tub , shower , etc . Better accommodations in africa
Stayed 1 night in Oct 2025

10/10 Excellent

Sheila

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Oct 2025

8/10 Good

Paula

Liked: Staff & service, amenities, property conditions & facilities
Our room smelled like it had been a smoking room previously. Also the spa was nice but made a loud noise with the jets on.
Stayed 2 nights in Aug 2025

8/10 Good

william

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Room ok
Stayed 1 night in Sep 2025

10/10 Excellent

Richard

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

4/10 Poor

Pat

Traveled with partner
Disliked: Staff & service, amenities
There was no one at the front desk, had to pick up a phone to get someone to check us in. T.V. remote was very strange and very hard to operate. It had no numbers on it so had to figure out how to get the guide to come up and was difficult to even figure that out. Room smelled musty.Wouldn't stay there again.
Stayed 1 night in Sep 2025

8/10 Good

Michael L, Auxvasse

Stayed 1 night in Sep 2025

6/10 Okay

William

Traveled with family
Disliked: Property conditions & facilities
#1, the TV did not work at all. When i attempted to call the front desk, the phone would not woek, no dial tone. The place is old & needs updates and a good cleaning. Will not stay there again. The staff was friendly enough.
Stayed 1 night in Sep 2025

6/10 Okay

Perry

Disliked: Property conditions & facilities
It just okay.
Stayed 2 nights in Sep 2025

2/10 Terrible

KELLY

Traveled with family
Disliked: Cleanliness, staff & service, amenities, property conditions & facilities
I think the hotel must have flooded at some point. There is a creek that runs next to it. The rooms SMELLED. We tried a couple different rooms and they both reeked of mildew and had visible mold on the wall. Thank god we were only there for one night because I could not have stayed any longer than that.
Stayed 1 night in Jul 2025

8/10 Good

Theresa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Clean. No issues. Would stay again.
Stayed 2 nights in Aug 2025

4/10 Poor

TIMOTHY

Liked: Staff & service
Disliked: Cleanliness, property conditions & facilities
Spa and pool were dirty and air quality in that area was poor.
Stayed 2 nights in Aug 2025

10/10 Excellent

William

Liked: Cleanliness, staff & service, property conditions & facilities
Nice property.
Stayed 1 night in Sep 2025

8/10 Good

sherry

Stayed 1 night in Aug 2025

Hotels