$52 Cheap flights to Madre de Dios Region
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Cheap flights to Madre de Dios Region from $52 One Way, $104 Round Trip
$104 return flights and $52 one-way flights to Madre de Dios Region were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
Find The Perfect Hotel For After Your Flight
Our Top Madre de Dios Region Apartment Hotels
CHIMICUAS HOUSE
"Very pleasant welcome to the city. Hospitable and very friendly.great place to come to after or before going to the jungle"
Reviewed on Oct 14, 2016
Score Epic Madre de Dios Region Accommodation Deals
IKAM Riverview Amazon Lodge - Asociado Casa Andina
"We had the best stay! We booked the airport transfers, tours, and all meals, and everything exceeded our expectations. The food was incredible, and the rooms were comfortable, clean, and had wonderful AC—a true relief after a day of exploring! All of the staff were so helpful, welcoming, and courteous. ..."
Reviewed on Oct 13, 2026
Tambopata Edosikiana Ecolodge
"Staff was helpful Otherwise nothing was amazing. Room was not too clean, food was okayish, no choice was given."
Reviewed on Jun 15, 2026
Inkaterra Reserva Amazonica
"Only remark is to enable electricity in the rooms during the day without interruption for fan and charging phones (solar panel with batteries for example). It was very hot and hard to rest in the room"
Reviewed on Jul 19, 2026
Ecolucerna Lodge Tambopata
"The experience was incredible. The eco tour, seeing a lot of wildlife from Caiman, sloth, monkey, tarantula, and a lot of different birds, we were very satisfied with the experience. The accommodations are a bit primative but nicer than we expected being out in the jungle. Food was very good,"
Reviewed on Sep 13, 2026
Family Friendly Hotels in Madre de Dios Region
Refugio Amazonas
Families like: Kids club, playground, babysitting, bicycle rentals
"We had an allergy problem. My son is allergic to tree nuts and peanuts. We made the staff and gm aware if it right away. They have all good labeled but had a chicken dish that said chicken and fruit. Come to find out it had Brazil nuts in it. As my son was taking his first bite of chicken ( it was ..."
Reviewed on Jun 3, 2026
Andean Wings Sotupa Eco Lodge
CHIMICUAS HOUSE
"Very pleasant welcome to the city. Hospitable and very friendly.great place to come to after or before going to the jungle"
Reviewed on Oct 14, 2016
Ecolucerna Lodge Tambopata
Families like: Playground, game room, close to beach, free breakfast for the whole family
"The experience was incredible. The eco tour, seeing a lot of wildlife from Caiman, sloth, monkey, tarantula, and a lot of different birds, we were very satisfied with the experience. The accommodations are a bit primative but nicer than we expected being out in the jungle. Food was very good,"
Reviewed on Sep 13, 2026
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Madre de Dios Region
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Frequently asked questions
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.