$74 Cheap flights to Madre de Dios Region
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Cheap flights to Madre de Dios Region from $74 One Way, $123 Round Trip
$123 return flights and $74 one-way flights to Madre de Dios Region were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
Find The Perfect Hotel For After Your Flight
Our Top Madre de Dios Region Apartment Hotels
CHIMICUAS HOUSE
"Very pleasant welcome to the city. Hospitable and very friendly.great place to come to after or before going to the jungle"
Reviewed on Oct 14, 2016
Score Epic Madre de Dios Region Accommodation Deals
Ecolucerna Lodge Tambopata
"we had a beautiful time at the lodge. the staff makes this property amazing! the food was so good, they are organized and friendly. same as other reviewers as no hot water, but its so hot out that a cool shower feels amazing!"
Reviewed on Oct 29, 2025
IKAM Riverview Amazon Lodge - Asociado Casa Andina
"Pros: the grounds were beautiful, comfy bed, AC. Cons: no services nearby, must take a taxi into town to get anywhere. Pricing of meals and activities not inclusive so you pay a lot at check out. There is nowhere else to eat so you have to eat there. The dinners were great, free breakfast was not ..."
Reviewed on Jun 9, 2026
Inkaterra Reserva Amazonica
"The lodge and the services were great and the Tours were excellent and Carlos our tour guide knew a lot about where to take us to see more animals. I will come back again to Inkaterra."
Reviewed on Jun 29, 2026
Libelula Hotel
"Good hotel! Recommend to book"
Reviewed on May 14, 2026
Family Friendly Hotels in Madre de Dios Region
Refugio Amazonas
Families like: Kids club, playground, babysitting, bicycle rentals
"We had an allergy problem. My son is allergic to tree nuts and peanuts. We made the staff and gm aware if it right away. They have all good labeled but had a chicken dish that said chicken and fruit. Come to find out it had Brazil nuts in it. As my son was taking his first bite of chicken ( it was ..."
Reviewed on Jun 3, 2026
Andean Wings Sotupa Eco Lodge
CHIMICUAS HOUSE
"Very pleasant welcome to the city. Hospitable and very friendly.great place to come to after or before going to the jungle"
Reviewed on Oct 14, 2016
Ecolucerna Lodge Tambopata
Families like: Playground, game room, close to beach, free breakfast for the whole family
"we had a beautiful time at the lodge. the staff makes this property amazing! the food was so good, they are organized and friendly. same as other reviewers as no hot water, but its so hot out that a cool shower feels amazing!"
Reviewed on Oct 29, 2025
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Madre de Dios Region
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Frequently asked questions
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.