DeSoto County Vacation Rentals

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DeSoto County Vacation Rentals

Spacious 5-bedroom house with WiFi, AC and parking in peaceful Southaven.

Spacious 5-bedroom house with WiFi, AC and parking in peaceful Southaven.

Southaven MS
At this vacation home, guests have access to features like laundry facilities.
Kitchen
Washer
Newly Constructed “AWARD WINNING” Cozy Home

Newly Constructed “AWARD WINNING” Cozy Home

Southaven MS
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Kitchen
Washer
Cozy Graceland Hot Tub Retreat 3BD/2Bath 🎶🎸

Cozy Graceland Hot Tub Retreat 3BD/2Bath 🎶🎸

Memphis TN
$353 nightly
The price is $413 total per night
$413 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of this vacation home enjoy a hot tub, an arcade/game room, and laundry facilities. Other amenities at this family-friendly vacation home include barbecue grills and a garden.
Hot Tub
Kitchen
3 Bed, 2 Bath Work Trip or Leisure ~ U of M area

3 Bed, 2 Bath Work Trip or Leisure ~ U of M area

Memphis TN
$220 nightly
The price is $259 total per night
$259 total
Dec 29 - Dec 30
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities.
Washer
Dryer
Charming Cottage in Hip Cooper Young - Walk to Food & Drink - 9 mins to Beale!

Charming Cottage in Hip Cooper Young - Walk to Food & Drink - 9 mins to Beale!

Memphis TN
$263 nightly
The price is $308 total per night
$308 total
Jan 19 - Jan 20, 2026
Total with taxes and fees
At this vacation home, guests have access to laundry facilities, local meal delivery service, and a garden. This smoke-free vacation home also has barbecue grills.
Kitchen
Washer
8 guests~Pool~Steam Room!~Great Midtown Memphis Location

8 guests~Pool~Steam Room!~Great Midtown Memphis Location

Memphis TN
$366 nightly
The price is $428 total per night
$428 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities.
Pool
Washer
The Stallion

The Stallion

4 out of 5
436 S Front St Memphis TN
$159 nightly
The price is $188 total per night
$188 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
At The Stallion, guests have access to free WiFi in public areas and laundry facilities. Free offsite parking is included with your stay. Staff members can help with accommodation requests, and provide luggage storage.
Kitchen
Washer
The Rambler

The Rambler

4 out of 5
400 S Main St Memphis TN
$149 nightly
The price is $176 total per night
$176 total
Dec 26 - Dec 27
Total with taxes and fees
Guests staying at The Rambler enjoy an outdoor pool, free WiFi in public areas, and a hot tub. Additional amenities include express check-in, express check-out, and a terrace.
Pool
Hot Tub
*Parkside KING SUITE in Midtown with FREE parking*

*Parkside KING SUITE in Midtown with FREE parking*

Memphis TN
$227 nightly
The price is $227 total per night
$227 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At this condo, guests have access to features like laundry facilities. This smoke-free condo building also has a garden.
Kitchen
Washer
The Downtown Bungalow Loft

The Downtown Bungalow Loft

Memphis TN
$188 nightly
The price is $222 total per night
$222 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This apartment features a gym and laundry facilities.
Washer
Dryer
Moody Blues Studio Perfect for Work or Romance

Moody Blues Studio Perfect for Work or Romance

2 out of 5
Memphis TN
$135 nightly
The price is $153 total per night
$153 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
This apartment features free WiFi in public areas and barbecue grills. This apartment building also has a garden.
Free WiFi
Outdoor Space
The Moose

The Moose

4 out of 5
669 Adams Ave Memphis TN
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $151 total per night
$151 total
Jan 14 - Jan 15, 2026
Total with taxes and fees
Guests of The Moose enjoy free WiFi in public areas, express check-in, and express check-out. Free parking is available if you drive. Additional amenities include laundry facilities, barbecue grills, and a water dispenser.
Kitchen
Washer
Cozy Highrise 2 br Apt - Downtown Memphis!

Cozy Highrise 2 br Apt - Downtown Memphis!

Memphis TN
$130 nightly
The price is $153 total per night
$153 total
Dec 28 - Dec 29
Total with taxes and fees
This apartment features a gym and laundry facilities. If you drive, take advantage of free offsite parking.
Washer
Dryer
Clean & Serene House + Studio - Easy On/off I-40

Clean & Serene House + Studio - Easy On/off I-40

2 out of 5
Memphis TN
$101 nightly
The price is $122 total per night
$122 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Free parking is available if you drive.
Pet friendly
Parking included
Clean & Serene Studio - easy on/off interstate

Clean & Serene Studio - easy on/off interstate

Memphis TN
$110 nightly
The price is $117 total per night
$117 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Guests staying at this apartment have access to a garden and barbecue grills.
Pet friendly
Free WiFi
Charming 3 Bedroom/2Bathroom Uptown Cottage with off-street Parking.

Charming 3 Bedroom/2Bathroom Uptown Cottage with off-street Parking.

Memphis TN
At this vacation home, guests have access to laundry facilities, local meal delivery service, and barbecue grills. This smoke-free vacation home also has a garden.
Kitchen
Washer
stayAPT Suites Memphis-Cordova-Wolfchase

stayAPT Suites Memphis-Cordova-Wolfchase

4 out of 5
1667 Chickering Ln Cordova TN
$109 nightly
The price is $131 total per night
$131 total
Dec 26 - Dec 27
Total with taxes and fees
Guests staying at stayAPT Suites Memphis-Cordova-Wolfchase enjoy free WiFi in public areas, laundry facilities, and barbecue grills. If you drive, put free parking to good use. This smoke-free aparthotel also has a vending machine.
Kitchen
Parking included
Eclectic 4 Bedroom Getaway with Private Pool!

Eclectic 4 Bedroom Getaway with Private Pool!

Memphis TN
$411 nightly
The price is $481 total per night
$481 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Guests staying at this vacation home enjoy an outdoor pool, an arcade/game room, and laundry facilities. Additional amenities include barbecue grills and a garden.
Pool
Kitchen
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in DeSoto County

    Drury Inn & Suites Memphis Southaven

    Drury Inn & Suites Memphis Southaven

    735 Goodman Rd W. Horn Lake MS
    $100 nightly
    The price is $111 total per night from Dec 28 to Dec 29
    $111 total
    Dec 28 - Dec 29
    Total with taxes and fees
    9.2/10 Wonderful! (1,005 reviews)
    avid hotel Memphis - Southaven by IHG

    avid hotel Memphis - Southaven by IHG

    6863 Hospitality Lane Southaven MS
    $96 nightly
    The price is $106 total per night from Dec 26 to Dec 27
    $106 total
    Dec 26 - Dec 27
    Total with taxes and fees
    8.8/10 Excellent! (1,004 reviews)
    Homestay Horn Lake / Southaven MS

    Homestay Horn Lake / Southaven MS

    6851 Interstate Blvd, I-55 Exit 289 Horn Lake MS
    $68 nightly
    The price is $76 total per night from Jan 22 to Jan 23
    $76 total
    Jan 22 - Jan 23, 2026
    Total with taxes and fees
    7.2/10 Good! (997 reviews)

Orbitz makes it easy to find vacation rentals in DeSoto County 

🏠 What is the best price for a DeSoto County vacation rental?


DeSoto County rentals range between $76 and $481 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in DeSoto County can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next DeSoto County getaway. Orbitz filters your search results so you can find the best DeSoto County vacation rental for you. We have tons of options.


🏠 Are cancellations free on DeSoto County vacation rentals with Orbitz?


You may be able to cancel or amend your DeSoto County vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in DeSoto County?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in DeSoto County by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My TripsOpens in a new window on your Orbitz account page to find the right information contact. If you need more help, visit our Customer ServiceOpens in a new window page. 


🏠 What are the advantages of booking a vacation rental in DeSoto County?


When you book a DeSoto County vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in DeSoto County?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across DeSoto County—with plenty of hidden gems. We also have plenty of inventory in DeSoto County main cities and near popular attraction spots.


🏠 Why should I book my DeSoto County vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream DeSoto County vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


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