Book 2 Star Hotels in Sikeston
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Featured Sikeston 2 Stars Hotels

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.13 mi from city center
$90 nightly
The price is $103 total per night
$103 total
Dec 29 - Dec 30
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.46 mi from city center
$98 nightly
The price is $110 total per night
$110 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Best Western Plus Sikeston
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.35 mi from city center
$76 nightly
The price is $86 total per night
$86 total
Dec 29 - Dec 30
Total with taxes and fees
Guests of Best Western Plus Sikeston have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.

Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.06 mi from city center
$75 nightly
The price is $86 total per night
$86 total
Dec 29 - Dec 30
Total with taxes and fees
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and a business center.
Pool
Hot Tub

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.07 mi from city center
$55 nightly
The price is $63 total per night
$63 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) enjoy free WiFi in public areas, coffee in a common area, and a vending machine. If you drive, take advantage of free parking. The 24-hour front desk has staff always at the ready.

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.34 mi from city center
$63 nightly
The price is $72 total per night
$72 total
Dec 28 - Dec 29
Total with taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
Breakfast included
Pet friendly

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
Free Cancellation
Reserve now, pay when you stay
2.87 mi from city center
$59 nightly
The price is $68 total per night
$68 total
Dec 28 - Dec 29
Total with taxes and fees
Guests staying at Super 8 by Wyndham Sikeston/Miner Area enjoy free WiFi in public areas, a library, and a vending machine. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Breakfast included
Pet friendly

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.56 mi from city center
$101 nightly
The price is $114 total per night
$114 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Guests of Fairfield Inn & Suites by Marriott Sikeston enjoy an indoor pool, free WiFi in public areas, and coffee in a common area. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and securing valuables. This hotel also has laundry facilities.
Pool
Breakfast included

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Free Cancellation
1.41 mi from city center
$105 nightly
The price is $119 total per night
$119 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston hotels essential information
Accommodation | 281 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $119 |
Popular hotels | Drury Inn & Suites Sikeston, MO, Hampton Inn Sikeston, Best Western Plus Sikeston, Pear Tree Inn Sikeston, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67), Days Inn and Suites by Wyndham Sikeston, Super 8 by Wyndham Sikeston/Miner Area, Fairfield Inn & Suites by Marriott Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG |
Recent Reviews

Hampton Inn Sikeston
5/5 Excellent
"Everything we just lovely "
A verified traveler stayed at Hampton Inn Sikeston
Posted 4 days ago


