Book 2 Star Hotels in Louisiana
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Louisiana 2 Stars Hotels

River's Edge Motel
201 Mansion St Louisiana MO
Free Cancellation
Reserve now, pay when you stay
0.43 mi from city center
$80 nightly
The price is $91 total per night
$91 total
Dec 27 - Dec 28
Total with taxes and fees
Guests of River's Edge Motel enjoy features like free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included

The Eagles Nest Inn
215 Georgia St Louisiana MO
Free Cancellation
0.24 mi from city center
$105 nightly
The price is $119 total per night
$119 total
Dec 28 - Dec 29
Total with taxes and fees
At The Eagles Nest Inn, guests have access to features like coffee in a common area. If you plan to drive, free parking is available.
Parking included
Free WiFi

The Yellow Rose Historic Home
Louisiana MO
0.2 mi from city center
$306 nightly
The price is $314 total per night
$314 total
Dec 28 - Dec 29
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This family-friendly vacation home also has barbecue grills.
Kitchen
Washer

Cozy room located in historic downtown with a 5 minute walk to the riverfront!
Louisiana MO
0.24 mi from city center
$133 nightly
The price is $140 total per night
$140 total
Dec 27 - Dec 28
Total with taxes and fees
This bed & breakfast is a smoke-free bed & breakfast.
Air conditioning

Historic rooms near riverfront in downtown, Louisiana, MO
Louisiana MO
0.24 mi from city center
$133 nightly
The price is $133 total per night
$133 total
Dec 28 - Dec 29
Total with taxes and fees
This bed & breakfast is a smoke-free bed & breakfast.
Air conditioning

Comfort Inn & Suites - Hannibal
4000 Market St Hannibal MO
Free Cancellation
Reserve now, pay when you stay
24.81 mi from city center
$79 nightly
The price is $90 total per night
$90 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Comfort Inn & Suites - Hannibal features a full-service spa, an indoor pool, and a 24-hour gym. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this spa hotel include free WiFi in public areas, a hot tub, and conference space.
Pool
Hot Tub

Motel 6 Hannibal, MO
123 Huckleberry Heights Dr Hannibal MO
Free Cancellation
Reserve now, pay when you stay
24.85 mi from city center
$58 nightly
The price is $67 total per night
$67 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Motel 6 Hannibal, MO features free WiFi in public areas and a vending machine. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include an ATM and a fireplace in the lobby.
Pet friendly
Parking included

Quality Inn & Suites Hannibal West
120 Lindsey Drive Hannibal MO
Free Cancellation
Reserve now, pay when you stay
27.22 mi from city center
$70 nightly
The price is $81 total per night
$81 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Quality Inn & Suites Hannibal West have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

Sleep Inn & Suites Hannibal West
105 Lakeside Dr Hannibal MO
Free Cancellation
27.36 mi from city center
$97 nightly
The price is $112 total per night
$112 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At Sleep Inn & Suites Hannibal West, guests enjoy an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff always at the ready. Additional amenities include a business center, coffee/tea in a common area, and free newspapers.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Louisiana hotels essential information
Accommodation | 82 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $314 |
Popular hotels | River's Edge Motel, The Eagles Nest Inn, The Yellow Rose Historic Home, Cozy room located in historic downtown with a 5 minute walk to the riverfront!, Historic rooms near riverfront in downtown, Louisiana, MO, Quality Inn & Suites Hannibal West, Sleep Inn & Suites Hannibal West, Comfort Inn & Suites - Hannibal, Motel 6 Hannibal, MO |
Recent Reviews

Quality Inn & Suites Hannibal West
5/5 Excellent
"The hotel was a little out of the way from town, but the room was very spacious and very clean. Would definitely stay next time I’m traveling through town. "
A verified traveler stayed at Quality Inn & Suites Hannibal West
Posted 5 days ago


