Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

3.0 star property

Choose dates to view prices

Photo gallery for Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

A patio with wicker chairs and a round table with a fire pit.
Free daily on-the-go breakfast
Suite, 1 Bedroom, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
An indoor swimming pool with two lanes, safety railings, and lounge chairs.
Studio Suite, 1 King Bed, Non Smoking | Living area | LCD TV

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
1120 S Grange Ave, Sioux Falls, SD, 57105
  • Place, University of Sioux Falls
    ‪5 min walk‬
  • Place, Augustana College
    ‪11 min walk‬
  • Place, Falls Park
    ‪4 min drive‬
  • Airport, Sioux Falls, SD (FSD-Sioux Falls Regional)
    ‪10 min drive‬

Room options

Studio Suite, 1 King Bed, Non Smoking

9.4 out of 10
Exceptional
(31 reviews)
  • 435 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Studio, 2 Queen Beds, Non Smoking

9.4 out of 10
Exceptional
(13 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

Suite, 1 Bedroom, Non Smoking

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Studio, 1 King Bed, Accessible, Non Smoking

7.4 out of 10
Good
(3 reviews)
  • 435 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Studio, 1 King Bed, Accessible, Bathtub

9.6 out of 10
Exceptional
(4 reviews)
  • 430 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Studio, 2 Queen Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(6 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

Studio, 2 Queen Beds, Accessible, Bathtub

9.0 out of 10
Wonderful
(2 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

Studio, 2 Queen Beds, Accessible, Non Smoking

9.2 out of 10
Wonderful
(5 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

Suite, 1 King Bed, Accessible, Bathtub

10.0 out of 10
Exceptional
(1 review)
  • 527 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Suite, 1 King Bed, Accessible, Non Smoking

  • 530 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Suite, 1 King Bed, Accessible, Non Smoking

  • 530 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Suite, 1 King Bed, Accessible, Non Smoking

  • Sleeps 4
  • Free WiFi

Suite, 1 King Bed, Accessible, Bathtub

  • Sleeps 4
  • Free WiFi

Studio, 1 King Bed, Accessible, Non Smoking

  • Sleeps 4
  • Free WiFi

You may also like

About the neighborhood

Sioux Falls

Located in University Heights, Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is adjacent to Sanford USD Medical Center and within a 5-minute walk of Sioux Empire Medical Museum. This 80-room, 3-star hotel has free breakfast along with conveniences like an indoor pool and a 24-hour gym.

What's nearby

  • University of Sioux Falls - 5 min walk - 0.3 miles
  • Sioux Empire Medical Museum - 6 min walk - 0.4 miles
  • Augustana College - 11 min walk - 0.6 miles
  • Washington Pavilion of Arts and Science - 3 min drive - 1.1 miles
  • Falls Park - 4 min drive - 1.5 miles

Getting around

  • Sioux Falls Regional Airport (FSD) - 8 min drive

Restaurants

  • ‪Casey's - ‬12 min walk
  • ‪Perch - ‬18 min walk
  • ‪Taco Bell - ‬14 min walk
  • ‪Taco John's - ‬3 min drive
  • ‪Fryn' Pan - ‬2 min drive

About this property

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Guests staying at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include conference space, a business center, and express check-out.
42-inch LCD TVs are available for entertainment, and guests can stay connected with free WiFi. Other standard amenities include kitchens, sofa beds, and refrigerators. Weekly housekeeping is available.
Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Free in-room WiFi has a 3-device limit
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free on-the-go breakfast available daily 6:00 AM to 9:00 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Indoor pool
  • Laundry facilities
  • Living room

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Housekeeping (weekly)

Business services

  • 950 square feet of conference space
  • Business center

Outdoors

  • Barbecue grill

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Braille/raised signage
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 4 floors
  • Built in 2014
  • Designated smoking areas (fines apply)

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed

Bathroom

  • Private bathroom
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 42-inch LCD TV

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Iron/ironing board
  • Living room
  • Phone

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 11:00 PM
Early check-in subject to availability
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Late check-out subject to availability
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
This property doesn't offer after-hours check-in
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 50 per accommodation, per stay
  • Dogs and cats only
  • 2 total (50 lbs is the maximum weight per pet)
  • Service animals exempt from fees

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 50 per accommodation, per stay
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Noise-free guestrooms cannot be guaranteed
  • Check-in: 3:00 PM
  • Check-out: noon
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking out is easy with express services. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards, debit cards, and cash.

Additional information about polices, regulations, and more:

  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.
  • Noise-free rooms can't be guaranteed.
  • Free in-room WiFi has a 3-device limit.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Home2 Suites Hilton Sioux Falls/Sanford Hotel
Home2 Suites Hilton Falls/Sanford Hotel
Home2 Suites Hilton Sioux Falls/Sanford
Home2 Suites Hilton Sioux Falls/Sanford Hotel
Home2 Suites Hilton Falls/Sanford Hotel
Home2 Suites Hilton Sioux Falls/Sanford
Home2 Suites Hilton Falls/Sanford
Hotel Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center Hotel

Frequently asked questions

Are free cancellation options available at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offers free cancellation on some room rates. For additional details, look at the cancellation policy on our site.

How much does it cost to stay at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

As of Jul 11, 2026, prices found for a 1-night stay for 2 adults at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center on Jul 19, 2026 start from $146, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do within easy reach of Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

This hotel is situated in University Heights, just steps from Sioux Empire Medical Museum. You'll also find Falls Park and Denny Sanford Premier Center within a short drive.

Is there parking available at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Yes, self parking is offered for free at the hotel. Wheelchair-accessible van parking is also available for guests.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a casino at the property?

No, Home2 Suites By Hilton Sioux Falls/Sanford Medical Center doesn't have a casino.

Is there an indoor pool at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Yes, this hotel has an indoor pool.

What do couples enjoy most about Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Couples staying at this hotel will appreciate amenities like a kitchen as well as an indoor pool and a free daily breakfast.

Are there hot tubs at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

No, this hotel doesn't have a spa tub.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a restaurant that serves breakfast?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offers free on-the-go breakfast each morning though there is no restaurant.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center allow pets to stay free of charge?

Although they can't stay for free, cats and dogs are welcome at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center for a fee of USD 50 per accommodation, per stay.

Are there connecting rooms at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Yes, this hotel has connecting rooms you can book for your group event or vacation.

What is the closest airport to Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

The closest major airport to Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is Sioux Falls Regional Airport (FSD), which is 4 mi away (8 minutes by car).

Are there rooms with balconies at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

No, there aren't any guestrooms with balconies at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center.

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 500 out of 656 reviews
Rating 8 - Good. 111 out of 656 reviews
Rating 6 - Okay. 27 out of 656 reviews
Rating 4 - Poor. 9 out of 656 reviews
Rating 2 - Terrible. 9 out of 656 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was substantial and tasty.
Stayed 2 nights in Apr 2026
Verified

8/10 Good

Jodie

Was great
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Debbie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was very clean and comfortable. The staff was very helpful.
Stayed 1 night in Apr 2026
Verified

8/10 Good

Stephanie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was amazing and my room was lovely and clean. So convenient to the Sanford Hospital.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Shyanne

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Staff was very friendly, rooms were clean. The stay was amazing
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Shawn

Liked: Cleanliness, staff & service, property conditions & facilities
Pleasant place
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was really good! It seemed to use healthier ingredients. The rooms were clean and everyone was very helpful.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Natalie

Liked: Cleanliness, staff & service, property conditions & facilities
Clean room | Breakfast Great | Wonderful and Helpful Staff
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Tracey

Liked: Cleanliness, staff & service, property conditions & facilities
This is a great hotel - centrally located and very clean and quiet. Will definitely be staying there again.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Angie

Liked: Cleanliness, amenities, property conditions & facilities
Great hotel
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room, quiet
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

jacquelyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location, nice clean property, Starbucks is available if you take a quick walk over the skyway to the hospital. Breakfast was good, wish they offered more fresh fruit or biscuits and gravy, but they had many options for breakfast sandwiches.
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Diane

Liked: Cleanliness, amenities, property conditions & facilities
Staff was very friendly, room was clean
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Connie

Liked: Cleanliness, staff & service, property conditions & facilities
Brought my sister-in-law to Sioux Falls for same-day surgery and we spent the night before here. The young woman at the front desk when we checked in and also the next morning was absolutely wonderful and very nice. I’m very impressed with the hotel. Breakfast was OK nothing special but you didn’t walk away hungry either other than that I say it’s a fantastic place to stay.
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Drew

Liked: Cleanliness, staff & service, property conditions & facilities
Great stay, love the skybridge to the hospital!
Stayed 5 nights in Nov 2025
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, amenities, property conditions & facilities
The room was spotless and the staff was very efficient and personable
Stayed 1 night in Jan 2026
Verified

8/10 Good

Stacy

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, staff very helpful.
Stayed 5 nights in Oct 2025
Verified

10/10 Excellent

Brandy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Destiny was friendly kind and professional. The room was vey clean and comfortable. I lived my stay.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

claudia

Liked: Cleanliness, amenities, property conditions & facilities
Great hospitality and clean service
Stayed 7 nights in Oct 2025
Verified

8/10 Good

rhonda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Extremely convenient and well maintained property.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
All of it was clean and well maintained
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Lucas

Liked: Cleanliness, amenities, property conditions & facilities
Spotless, spacious, well stocked room that smelled good.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Kyle

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay!
Stayed 1 night in Apr 2023
Verified

10/10 Excellent

Kim

Liked: Cleanliness, property conditions & facilities
The staff was so wonderful! Destynee was so kind, her smile just lifted my spirits. The room was comfortable and spotless. Would definitely stay here again!
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Darrell

Liked: Cleanliness, property conditions & facilities
The room was clean and the place is quiet. It was a nice visit.
Stayed 2 nights in Nov 2025