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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Sikeston

    Auburn Place Hotel And Suites

    Auburn Place Hotel And Suites

    3265 William St, Cape Girardeau, MO
    The price is $69 per night from May 17 to May 17
    4.3/5Excellent! (34 reviews)
    Auburn Place Hotel And Suites
    Drury Plaza Hotel Cape Girardeau Conference Center

    Drury Plaza Hotel Cape Girardeau Conference Center

    3351 Percy Drive, Cape Girardeau, MO
    The price is $108 per night from May 18 to May 18
    4.9/5Exceptional! (7 reviews)
    Drury Plaza Hotel Cape Girardeau Conference Center
    Courtyard by Marriott Cape Girardeau Downtown

    Courtyard by Marriott Cape Girardeau Downtown

    400 Broadway St., Cape Girardeau, MO
    The price is $135 per night from Jun 6 to Jun 6
    4.9/5Exceptional! (9 reviews)
    Courtyard by Marriott Cape Girardeau Downtown